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| 1 | Cytoplasmic m6A reader YTHDF3 promotes mRNA translation显示文摘 | Ang Li Yu-Sheng Chen Xiao-Li Ping Xin Yang Wen Xiao Ying Yang Hui-Ying Sun Qin Zhu Poonam Baidya Xing Wang Devi Prasad Bhattarai Yong-Liang Zhao Bao-Fa Sun Yun-Gui Yang | 2017 | Cell Research2017，27，3： | 82 |
| 2 | Mineralogy and carbothermal reduction behaviour of vanadium-bearing titaniferous magnetite ore in Eastern India显示文摘Vanadium-bearing titaniferous magnetite bands hosted by Precambrian gabbro-norite-anorthositic rocks or their metamorphic equivalents were discovered in some parts of Eastern Indian Shield,containing 48%-49%Fe(total),10%-25%TiO2,and 0.3%-2.20%V2O5by mass.Mineralogical and petrological study,composition,and characterization of the vanadium-bearing titaniferous magnetite ore were carried out by scanning electron microscopy-energy dispersive X-ray(SEM-EDX),wave length X-ray florescence(WDXRF),inductively coupled plasma-atomic emission spectroscopy(ICP-AES),X-ray difraction(XRD),etc.Chemical beneficiation for valuable metals,such as Fe,Ti,and V,was performed by reduction roasting.The direct and indirect reduction were investigated by mixing the lump ore with solid activated charcoal in a closed reactor and purging the reducing gas mixture in standard reducibility index apparatus at diferent temperatures and time intervals.The reduction roasting parameters were optimized.Finally,the reduced samples were crushed and upgraded by magnetic separation.The results show that,the maximum mass fractions of magnetic and nonmagnetic parts achieved are 69.36%and 30.64%,respectively,which contain 10.6%TiO2and 0.84%V2O5in the magnetic part and 36.5%TiO2and 0.22%V2O5in the nonmagnetic part. | Saikat Samanta Manik Chandra Goswami Tapan Kumar Baidya Siddhartha Mukherjee Rajib Dey | 2013 | International Journal of Minerals,Metallurgy and Materials2013，20，10： | 9 |
| 3 | Acanthus ilicifolius plant extract prevents DNA alterations in a transplantable Ehrlich ascites carcinoma-bearing murine model显示文摘AIM: To investigate the chemopreventive efficacy of the Indian medicinal plant Acanthus ilicifolius L Acanthaceae in a transplantable Ehrlich ascites carcinoma (EAC)- bearing murine model. METHODS: Male Swiss albino mice were divided into four groups: Group A was the untreated normal control; Group B was the EAC control mice group that received serial, intraperitoneal (ip) inoculations of rapidly proliferating 2 x 105 viable EAC cells in 0.2 mL of sterile phosphate buffered saline; Group C was the plant extract-treated group that received the aqueous leaf extract (ALE) of the plant at a dose of 2.5 mg/kg body weight by single ip injections, once daily for 10, 20 and 30 consecutive days following tumour inoculation (ALE control); and Group D was the EAC + ALE- treatment group. The chemopreventive potential of the ALE was evaluated in a murine model by studying various biological parameters and genotoxic markers, such as tumour cell count, mean survival of the animals, haematological indices, hepatocellular histology, immunohistochemical expression of liver metallothionein (MT) protein, sister-chromatid exchanges (SCEs), and DNA alterations.RESULTS: Treatment of the EAC-bearing mice with the ALE significantly (P < 0.001) reduced viable tumour cell count by 68.34% (228.7 x 106 ± 0.53) when compared to EAC control mice (72.4 x 106 ± 0.49), and restored body and organ weights almost to the normal values. ALE administration also increased (P < 0.001) mean survival of the hosts from 35 ± 3.46 d in EAC control mice to 83 ± 2.69 d in EAC + ALE-treated mice. Haematological indices also showed marked improvement with administration of ALE in EAC-bearing animals. There was a significant increase in RBC count (P < 0.001), hemoglobin percent (P < 0.001), and haematocrit value (P < 0.001) from 4.3 ± 0.12, 6.4 ± 0.93, and 17.63 ± 0.72 respectively in EAC control mice to 7.1 ± 0.13, 12.1 ± 0.77, and 30.23 ± 0.57 respectively in EAC + ALE-treated group, along with concurrent decrement (P < 0.001) in WBC count from 18.8 ± 0.54 in EAC control to 8.4 ± 0.71 in EAC + ALE. Furthermore, treatment with ALE substantially improved hepatocellular architecture and no noticeable neoplastic lesions or foci of cellular alteration were observed. Daily administration of the ALE was found to limit liver MT expression, an important marker of cell proliferation with concomitant reduction in MT immunoreactivity (62.25 ± 2.58 vs 86.24 ± 5.69, P < 0.01). ALE was also potentially effective in reducing (P < 0.001) the frequency of SCEs from 14.94 ± 2.14 in EAC control to 5.12 ± 1.16 in EAC + ALE-treated group. Finally, in comparison to the EAC control, ALE was able to suppress in vivo DNA damage by abating the generations of ‘tailed’ DNA by 53.59% (98.65 ± 2.31 vs 45.06 ± 1.14, P < 0.001), and DNA single-strand breaks (SSBs) by 38.53% (3.14 ± 0.31 vs 1.93 ± 0.23, P < 0.01) in EAC-bearing murine liver. CONCLUSION: Our data indicate that, ALE is beneficial in restoring haematological and hepatic histological profiles and in lengthening the survival of the animals against the proliferation of ascites tumour in vivo. Finally, the chemopreventive efficacy of the ALE is manifested in limiting MT expression and in preventing DNA alterations in murine liver. The promising results of this study suggest further investigation into the chemopreventive mechanisms of the medicinal plant A. ilicifolius in vivo and in vitro. | Tridib Chakraborty Dipak Bhuniya Mary Chatterjee Mosiur Rahaman Dipak Singha Baidya Nath Chatterjee Subrata Datta Ajay Rana Kartick Samanta Sunil Srivastawa Sankar K Maitra Malay Chatterjee | 2007 | World Journal of Gastroenterology2007，13，48： | 2 |
| 4 | Image thresholding by variational minimax optimization显示文摘 | Baidya Nath Saha Nilanjan Ray | 2009 | Pattern Recognition2009，42，： | 1 |
| 5 | Higher catalytic activity of nano- Ce1-x-yTixPdyO2-δ compared to nano-Ce1-xPdxO2-δ for CO oxidation and N2O and NO reduction by CO: role of oxide ion vacancy显示文摘 | BAIDYA T MARIMUTHU A HEGDE M S RAVISHANKAR N MADRAS G | 2007 | Journal of Physical Chemistry C2007，111，： | 1 |
| 6 | T helper cell related interleukins and the angiographic morphology in unstable angina 显示文摘 | Baidya SG Zeng QT Wang X | 2005 | Cytokine2005，30，5： | 1 |
| 7 | Role of nitric oxide and flavohemoglobin homolog genes in Aspergillus nidulans sexual development and mycotoxin production显示文摘 | Baidya S Cary J W Grayburn W S | 2011 | Applied and Environmental Microbiology2011，8，： | 1 |
| 8 | Assessment of Tomographic PIV in Wall-bounded Turbulence Using Direct Numerical Simulation Data显示文摘 | Silva C M Baidya R Khashehchi M | 2012 | Experiments in Fluids2012，52，2： | 1 |
| 9 | Analgesic efficacy and safety of thoracic paravertebral and epidural analgesia for thoracic surgery: a systematic review and meta-analysis显示文摘 | Baidya DK Khanna P Maitra S | 2014 | Interactive cardiovascu- tar and thoracic surgery2014，18，5： | 1 |
| 10 | Helper T cells and atherosclerosis:the cytokine web 显示文摘 | Baidya SG Zeng QT | 2005 | Postgrad Med J2005，81，962： | 1 |
| 11 | Kinetics of Removal of Carbon Dioxide by Aqueous Solutions of N,N- Diethylethanolamine and Piperazine 显示文摘 | Konduku P Baidya P Kenig E | 2010 | Environ Sci Technol2010，44，： | 1 |
| 12 | HELPER T ceils and atherosclerosis: the cytokine web显示文摘 | BAIDYA S G ZENG Q T | 2005 | Postgrad Med J2005，81，： | 1 |
| 13 | Perioperative complications of cochlear implant surgery in children显示文摘 | Darlong V Khanna P Baidya DK | 2015 | JAnesth2015，29，1： | 1 |
| 14 | Dynamic response of footing on a sand layer of thickness显示文摘 | Baidya D K Rathi | 2004 | Geotech Geoenviron Engrg ASCE2004，130，6： | 1 |
| 15 | Evaluation of tumor response to antiangiogenic therapy in patients with recurrent gliomas using contrast-enhanced perfusion-weighted magnetic resonance imaging techniques:A meta-analysis显示文摘BACKGROUND It is of vital importance to find radiologic biomarkers that can accurately predict treatment response. Usually, the initiation of antiangiogenic therapy causes a rapid decrease in the contrast enhancing tumor. However, the treatment response is observed only in a fraction of patients due to the partial radiological response secondary to stabilization of abnormal vessels which does not essentially indicate a true antitumor effect. Perfusion-weighted magnetic resonance imaging(PWMRI) techniques have shown implicitness as a strong imaging biomarker for gliomas since they give hemodynamic information of blood vessels. Hence, there is a rapid expansion of PW-MRI related studies and clinical applications.AIM To determine the diagnostic performance of PW-MRI techniques including:(A)dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI); and(B)dynamic susceptibility contrast magnetic resonance imaging(DSC-MRI) for evaluating response to antiangiogenic therapy in patients with recurrent gliomas.METHODS Databases such as PubMed(MEDLINE included), EMBASE, and Google Scholar were searched for relevant original articles. The included studies were assessed for methodological quality with the Quality Assessment of Diagnostic Accuracy Studies 2 tool. Medical imaging follow-up or histopathological analysis was used as the reference standard. The data were extracted by two reviewers independently, and then the sensitivity, specificity, summary receiver operating characteristic curve, area under the curve(AUC), and heterogeneity were calculated using Meta-Disc 1.4 software.RESULTS This study analyzed a total of six articles. The overall sensitivity for DCE-MRI and DSC-MRI was 0.69 [95% confidence interval(CI): 0.53-0.82], and the specificity was 0.99(95%CI: 0.93-1) by a random effects model(DerSimonianeeLaird model). The likelihood ratio(LR) +, LR-, and diagnostic odds ratio(DOR)were 12.84(4.54-36.28), 0.35(0.22-0.53), and 24.44(7.19-83.06), respectively. The AUC(± SE) was 0.9921(± 0.0120), and the Q* index(± SE) was 0.9640(± 0.0323).For DSC-MRI, the sensitivity was 0.73, the specificity was 0.98, the LR+ was 7.82,the LR-was 0.32, the DOR was 31.65, the AUC(± SE) was 0.9925(± 0.0132), and the Q* index was 0.9649(± 0.0363). For DCE-MRI, the sensitivity was 0.41, the specificity was 0.97, the LR+ was 5.34, the LR-was 0.71, the DOR was 8.76, the AUC(± SE) was 0.9922(± 0.2218), and the Q* index was 0.8935(± 0.3037).CONCLUSION This meta-analysis demonstrated a beneficial value of PW-MRI(DSC-MRI and DCE-MRI) in monitoring the response of recurrent gliomas to antiangiogenic therapy, with reasonable sensitivity, specificity, +LR, and-LR. | Akanganyira Kasenene Aju Baidya Salman Shams Hai-Bo Xu | 2019 | World Journal of Meta-Analysis2019，7，2： | 1 |
| 16 | Dynamic response of footing on a sand layer of thickness显示文摘 | Baidya D K Rathi A | 2004 | J Geotech Geoenviron Engrg ASCE2004，130，6： | 1 |
| 17 | Six novel mutation including triple heterozygosity for Phe 31 Ser,514 delT and 516 T(G factor X gene mutation are responsible for congenital factor X deficiency in patients of Nepali and Indian origin显示文摘 | VISWABANDYA A BAIDYA S | 2005 | Thromb Haemost2005，3，7： | 1 |
| 18 | Materials Research Bulletin显示文摘 | Manjunath B Bellakki Shivakumara C Tinku Baidya | 2008 | 43(10):26582008，43，10： | 1 |
| 19 | Dynamic response of footing on a sand layer of thickness 显示文摘 | Baidya D K Rathi A | 2004 | Journal of Geotechnical and Geoenvironmental Engineering ASCE2004，130，6： | 1 |
| 20 | VeA is associated with the response to oxidative stress in the aflatoxin producer Aspergillus flavus显示文摘 | Baidya S Duran R Lohmar JM | 2014 | Eukaryotic Cell2014，13，8： | 1 |
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