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| 1 | The emergence of drug resistant HIV variants and novel anti-retroviral therapy显示文摘After its identification in 1980s,HIV has infected more than 30 million people worldwide.Inthe era of highly active anti-retroviral therapy,anti-retroviral drug resistance results frominsufficient anti-retroviral pressure,which may lead to treatment failure.Preliminary studiessupport the idea that anti-retroviral drug resistance has evolved largely as a result of low-adherence of patients to therapy and extensive use of anti-retroviral drugs in the developedworld;however,a highly heterogeneous horde of viral quasi-species are currently circulating indeveloping nations.Thus,the prioritizing of strategies adopted in such two worlds should be quitedifferent considering the varying anti-retroviral drug resistance prevalence.In this article,weexplore differences in anti-retroviral drug resistance patterns between developed and developingcountries,as they represent two distinct ecological niches of HIV from an evolutionary standpoint. | Koosha Paydary Parisa Khaghani Sahra Emamzadeh-Fard Seyed Ahmad Seyed Alinaghi Kazem Baesi | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，7： | 5 |
| 2 | Right paraesophageal lymph node dissection in papillary thyroid carcinoma显示文摘 | BaeSY YangJH ChoiMY | 2012 | Ann Surg Oncol2012，19，99： | 1 |
| 3 | The immuno- modulatory effects of fish-oil supplementation in elite paddlers: a pilot randomized double blind placebo-controlled trial 显示文摘 | DELFANA M EBRAHIMB K BAESI F | 2015 | Prostaglandins Leukot Essent Fatty Acids2015，99，8： | 1 |
| 4 | Phylogenetic analysis of HIV-1 pol gene: first subgenomic evidence of CRF29-BF among Iranian HIV-1 patients显示文摘 | Kazem Baesi Samaneh Moallemi Mehrdad Ravanshad | 2014 | Asian Pacific Journal of Tropical Disease2014，，： | 1 |
| 5 | Antiretroviral drug resistance among antiretroviral‐na?ve and treatment experienced patients infected with HIV in Iran显示文摘 | Kazem Baesi Mehrdad Ravanshad Maryam Ghanbarisafari Esmaeil Saberfar SeyedAhmad SeyedAlinaghi Jonathan E. Volk | 2014 | J. Med. Virol2014，，7： | 1 |
| 6 | Phylogeny and drug resistance of HIV PR gene among HIV patients receiving RT inhibitors in Iran显示文摘Objective: To survey the level and patterns of reverse transcriptase-based drug resistance and subtype distribution among antiretroviral-treated HIV-infected patients receiving only reverse transcriptase inhibitors in Iran.Methods: A total of 25 samples of antiretroviral therapy experienced patients with no history of using protease inhibitors were collected. After RNA extraction, reverse transcriptase-nested PCR was performed. The final products were sequenced and then analysed for drug-resistant mutations and subtypes.Results: No drug resistant mutations were observed among the 25 subjects. The results showed the following subtypes among patients: CRF 35_AD(88%), CRF 28_BF(8%),and CRF 29_BF(4%).Conclusions: A significant increase in drug resistance has been noted in recentlyinfected patients worldwide. Subtype distributions are needed to perform properlydesigned surveillance studies to continuously monitor rates and patterns of transmitted drug resistance and subtypes to help guide therapeutic approaches and limit transmission of these variants. | Kazem Baesi Majedeh Moradbeigi Mehrdad Ravanshad Ashrafolnesa Baghban | 2016 | Asian Pacific Journal of Tropical Biomedicine2016，6，5： | 0 |
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