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15篇 您的检索式:作者名="Backus HH"
    题名 作者 年代 出处 被引量
1Induction of resistance to the multitargeted antifolate Pemetrexed(ALIMTA) in WiDr human colon cancer cells is associate with thymidylate synthase overexpression 显示文摘Sigmond J Backus HH Wouters D 2003Biochem Pharmacol2003,66,3:1
2Induction of resistance to the multitargeted antifolate pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression显示文摘Sigmond J Backus HH Wouters D 2003Biochem Pharmacol2003,66,3:1
3Induction of resistance to the multitargeted antifolate pemetrexed (ALIMTA) in WiDr human colon cancer cells is associate with thymidylate synthase overexpressiou 显示文摘Sigmond J Backus HH Wouters D 2003Biochem Pharmacol2003,66,3:1
45-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients显示文摘Backus HH Dukers DF van-Groeningen CJ 2001Ann Oncol2001,12,2:1
55-fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients显示文摘Backus HH Dukers DF van Groeningen CJ 2001Ann Oncol2001,12,2:1
6Induction of resistance to the multitargeted antifolate pemetrexed (ALIM TA) in WiDr human coloncancer cells is associated with thymi dylate synthase overcxpression 显示文摘Sigmond J Backus HH Wouters D 2003Biochem Pharmacol2003,66,3:1
7Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates显示文摘Backus HH Pinedo HM Wouters D 2000Int J Cancer2000,87,6:1
8Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels显示文摘GIOVANNETTI E BACKUS HH WOUTERS D 2007BrJ Cancer2007,96,5:1
9Induction of thymidylate synthase as a 5 - fluorouracil resistance mechanism 显示文摘Peters GJ Backus HH Freemantle S 2002Biochim Biophys Acta2002,1587,23:1
105-Fluorouracil induced Fas upregulation associated with apoptosis in livermetastases of colorectal cancer patients cells显示文摘Backus HH Dukers DF van Groeningen CJ 1992Cell Physiol1992,152,3:1
11Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed显示文摘Peters GJ Van TB Backus HH 2000Eur J Cancer2000,36,7:1
12Rb,mcl-1 and p53 expression correlate with clinical outcome in patients with liver metastases from colorectal cancer显示文摘Backus HH van Riel JM van Groeningen CJ 2001Ann Oncol2001,12,6:1
13Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism显示文摘 Backus HH Freemantle S 2002Biochim Biophys Acta2002,1587,23:1
14Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates 显示文摘Backus HH Pinedo HM Wouters D 2000Oncol Res2000,12,:1
15Rb, mcl-1 and p53 expression correlate with clinical outcome in patients with liver metastases from colorectal cancer 显示文摘Backus HH van Riel JM van Groeningen C J 2001Ann Oneol2001,12,6:1
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