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| 1 | 内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑显示文摘营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,Jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。 | 刘青 叶鹏 Jabs M Rose AJ Lehmann LH Taylor J Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne HJ Hell R Okun JG Backs J Nawroth PP Herzig S Fischer A | 2018 | 中华高血压杂志2018，26，3： | 6 |
| 2 | Chronic antiepileptic drug use and functional network efficiency: A functional magnetic resonance imaging study显示文摘AIM To increase our insight in the neuronal mechanisms underlying cognitive side-effects of antiepileptic drug(AED) treatment.METHODS The relation between functional magnetic resonance-acquired brain network measures, AED use, and cognitive function was investigated. Three groups of patients with epilepsy with a different risk profile for developing cognitive side effects were included: A 'low risk' category(lamotrigine or levetiracetam, n=16), an 'intermediate risk' category(carbamazepine, oxcarbazepine, phenytoin, or valproate, n=34) and a 'high risk' category(topiramate, n=5). Brain connectivity was assessed using resting state functional magnetic resonance imaging and graph theoretical network analysis. The Computerized Visual Searching Task was used to measure central information processing speed, a common cognitive side effect of AED treatment. RESULTS Central information processing speed was lower in patients taking AEDs from the intermediate and high risk categories, compared with patients from the low risk category. The effect of risk category on global efficiency was significant(P < 0.05, ANCOVA), with a significantly higher global efficiency for patient from the low category compared with the high risk category(P < 0.05, post-hoc test). Risk category had no significant effect on the clustering coefficient(ANCOVA, P > 0.2). Also no significant associations between information processing speed and global efficiency or the clustering coefficient(linear regression analysis, P > 0.15) were observed. CONCLUSION Only the four patients taking topiramate show aberrant network measures, suggesting that alterations in functional brain network organization may be only subtle and measureable in patients with more severe cognitive side effects. | Tamar M van Veenendaal Dominique M IJff Albert P Aldenkamp Richard H C Lazeron Paul A M Hofman Anton J A de Louw Walter H Backes Jacobus F A Jansen | 2017 | World Journal of Radiology2017，9，6： | 2 |
| 3 | Pseudorapidity and centrality dependence of the collective flow of charged particles in Au + Au colli- sions at √SNN = 130 GeV显示文摘 | Back B B Baker M D Barton D S | 2002 | Phys Rev Lett2002，89，22： | 1 |
| 4 | Synthesis of end- functionalized poly ( methyl methacrylate) by ruthenium - catalyzed living radical polymerization with functionalized Initiators 显示文摘 | Back K Y Kamigaito M Sawamoto M | 2002 | Journal of Polymer Science: Part A: Polymer Chemistry2002，40，： | 1 |
| 5 | Maturation-dependent vulnerability of perinatal white matter in premature birth 显示文摘 | Back S A Riddle A McClure M M | 2007 | Stroke2007，38，2： | 1 |
| 6 | The effect of postoperative wound infections on functional outcome following intra-articular calcaneal fractures显示文摘 | Backes M Schep N W Luitse J S | 2015 | Archives of Orthopaedic&Trauma Surgery2015，135，8： | 1 |
| 7 | Adaptive niche ra dii and niche shapes approaches for niching with the CMA-ES显示文摘 | Shir O M Emmerieh M Back T | 2010 | Evolutionary Computation2010，18，1： | 1 |
| 8 | Traditional tonsillectomycompared with bipolar radiofrequency thermal ablationtonsillectomy in adults: a pilot study 显示文摘 | Back L Paiolheimo M Ylikoski J | 2001 | Arch Otolaryngol HeadNeck Surg2001，127，： | 1 |
| 9 | Matrix metalloproteinases in atherothrombosis显示文摘 | Back M Ketelhuth DF Agewall S | 2010 | Prog Cardiovasc Dis2010，52，5： | 1 |
| 10 | Study on the membrane filtration of mash with particular respect to the quality of wort and beer显示文摘 | Schneider J Krottenthaler M Back W | 2005 | Journal of the Institute of Brewing2005，111，4： | 1 |
| 11 | Preliminary results of a phase Ⅰ/ Ⅱ study of simultaneous modulated accelerated radiotherapy for nondisseminated nasophar yngeal carcinoma显示文摘 | Lee S W Back G M Yi B Y | 2006 | Int J Radiat Oncol Biol Phys2006，65，1： | 1 |
| 12 | Three-dimen sional image analysis of brain glucose melabolism-blood flow upcoupling and its dectrophysiological correlates in the acute ischemic penumbra following middle cerebral artery occlusion显示文摘 | BACK T ZHAO W Z GINSBERY M D | 1995 | J Cereb Blood Flow Metab1995，15，： | 1 |
| 13 | A Study on the Composite Dielectric Properties for an HTS Cable 显示文摘 | Kwag D S Nguyen V D Back S M | 2005 | IEEE Transactions on Applied Supercond - uctivity2005，15，2： | 1 |
| 14 | Constitutively wilted 1,a member of the rice YUCCA gene family,is required for maintaining water homeostasis and an appropriate root to shoot ratio显示文摘 | Woo Y M Park H J Su'udi M Yang J I Park J J Back K Park Y M An G | 2007 | Plant Molecular Biology2007，65，1： | 1 |
| 15 | Transanal single port microsurgery (TS PM) as a modified technique of transanal endoscopic microsurgery (TEM)显示文摘 | Lorenz C Nimmesgern T Back M | 2010 | Surg Innov2010，17，2： | 1 |
| 16 | Update on leukotriene, Iipoxin and oxoeicosanoid receptors: IUPHAR Review 7 显示文摘 | BACK M POWELL W S DAHLEN S E et a1 | 2014 | BrJPharmacol2014，171，15： | 1 |
| 17 | Reactivity of alkaline lignite fly ashes towards CO2 in water 显示文摘 | Back M Kuehn M Stanjek H | 2008 | Environmental Science and Technology2008，42，12： | 1 |
| 18 | Urine alhumin/creatinine ratio for the assessment of albuminuria in pregnancy hyperten- siom显示文摘 | Nisell H Trygg M Back R | 2006 | Acta Obstet Gynecol Scand2006，85，11： | 1 |
| 19 | A review of convention and meeting management research 1990 - 2003 显示文摘 | Lee M J Back K J | 2005 | Journal of Convention & Event Tourism2005，7，2： | 1 |
| 20 | Modification of ovalburnin in stored eggs detected by heat denaturation显示文摘 | Smith M B Back J F | | 0，，： | 1 |
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