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| 1 | Mechanobiology of bone tissue显示文摘 | Klein-Nulend J Bacabac RG Mullender MG | 2005 | Pathol Biol2005，53，10： | 1 |
| 2 | Mechanobiotogy of bone tissue显示文摘 | Klein-Nulend J Bacabac R.G Mullender M.G | | 0，，： | 1 |
| 3 | Nitric oxide production by bone cells is fluid shear stress rate depend- ent显示文摘 | Bacabac RG Smit TH Mullender MG | 2004 | Biochem Biophys Res Commun2004，315，4： | 1 |
| 4 | Nitric oxide production by bone cells is fluid sbear stress rate dependent显示文摘 | Bacabac R.G Smit T.H Mullender M.G | | 0，，： | 1 |
| 5 | Mechanical loading and how it affects bone cells:the role of the osteocyte cytoskeleton in maintaining our skeleton显示文摘 | Klein-Nulend J Bacabac R G Bakker A D | 2012 | Eur Cell Mater2012，24，： | 1 |
| 6 | Nitric oxide production by bone cells is fluid shear stress rate dependent 显示文摘 | Bacabac RG Smit TH Mullender MG | 2004 | Biochem Biophys Res Commun2004，19，315： | 1 |
| 7 | Mechanosensation and tranaduetion in osteocytes 显示文摘 | KLEIN-NULEND J BAKKER A D BACABAC R G | 2013 | Bone2013，54，2： | 1 |
| 8 | Mechanosensation and transduction in osteocytes显示文摘 | Klein-Nulend J Bakker AD Bacabac RG | 2013 | Bone2013，54，2： | 1 |
| 9 | Osteocyte shape and mechani- cal loading显示文摘 | van Oers RF Wang H Bacabac RG | 2015 | Curr Osteoporos Rep2015，13，2： | 1 |
| 10 | Noise en-hances the rapid nitric oxide production by bone cells inresponse to fluid shear stress 显示文摘 | Bacabac RG Van Loon JJ Smit TH | 2009 | Techno 1 HealthCare2009，17，1： | 1 |
| 11 | Release of nitric oxide, but not prostaglandin E2, by bone cells depends on fluid flow frequency显示文摘 | MULLENDER M G DIJCKS S J BACABAC R G | 2006 | J Or- thop Res2006，24，： | 1 |
| 12 | Dynamic shear stress in parallel-plate flow chambers显示文摘 | Bacabac R G Smit T H Cowin S C | 2005 | J Biomech2005，38，1： | 1 |
| 13 | Microgravity and bone cell mechanosensitivity 显示文摘 | Klein-Nulend J Bacabac RG Veldhuijzen JP | 2003 | Adv Space Res2003，32，8： | 1 |
| 14 | Microgravity and bone cell mechanosensitivity 显示文摘 | Klein - Nulend J Bacabac RG Veldhuijzen JP | 2003 | Adv Space Res2003，32，8： | 1 |
| 15 | Nitric oxide production by bone cells is fluid shear stress rate dependent 显示文摘 | Bacabac RG Smit TH Mullender MG | 2004 | Biochem Bioph Res Co2004，315，4： | 1 |
| 16 | Mechanobiology ofbone tissue显示文摘 | Klein-Nulend J Bacabac RG Mullender MG | 2005 | Pathol Bio(l Paris)2005，53，10： | 1 |
| 17 | Bone cell responses to high-frequency vibration stress:does the nucleus oscillate within the cytoplasm?显示文摘 | Bacabac RG Smit TH van Loon JJ | 2006 | FASEB J2006，20，7： | 1 |
| 18 | Bone cell re- sponses to high-frequency vibration stress:does the nucleus oscillate within the cytoplasm?显示文摘 | Bacabac RG Smit TH Van Loon JJ | 2006 | FASEB J2006，20，7： | 1 |
| 19 | Osteocyte morphology and orientation in relation to strain in the jaw bone显示文摘Bone mass is important for dental implant success and is regulated by mechanoresponsive osteocytes. We aimed to investigate the relationship between the levels and orientation of tensile strain and morphology and orientation of osteocytes at different dental implant positions in the maxillary bone. Bone biopsies were retrieved from eight patients who underwent maxillary sinus-floor elevation with β-tricalcium phosphate prior to implant placement. Gap versus free-ending locations were compared using 1) a three-dimensional finite-element model of the maxilla to predict the tensile strain magnitude and direction and 2) histology and histomorphometric analyses. The finite-element model predicted larger, differently directed tensile strains in the gap versus freeending locations. The mean percentage of mineralised residual native-tissue volume, osteocyte number(mean ± standard deviations:97 ± 40/region-of-interest), and osteocyte shape(~90% elongated, ~10% round) were similar for both locations. However, the osteocyte surface area was 1.5-times larger in the gap than in the free-ending locations, and the elongated osteocytes in these locations were more cranially caudally oriented. In conclusion, significant differences in the osteocyte surface area and orientation seem to exist locally in the maxillary bone, which may be related to the tensile strain magnitude and orientation. This might reflect local differences in the osteocyte mechanosensitivity and bone quality, suggesting differences in dental implant success based on the location in the maxilla. | Vivian Wu René F. M. van Oers Engelbert A. J. M. Schulten Marco No Helder Rommel G. Bacabac Jenneke Klein-Nulend | 2018 | International Journal of Oral Science2018，10，1： | 0 |
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