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| 1 | Heat shock induction of a 65 kDa ATP-binding proteinase in rat C6 glioma cells显示文摘The 45, 55, 65 and 100 kDa ATP-binding proteinases (ATP-BPases) of the heat-shocked (44 ℃ for 30 min, recovery for 12h) rat C6 glioma cells were purified by DEAE-ionexchange and ATP-affinity chromatography. Their molecular masses, isoelectric points (pI), pH-optima and other properties were analyzed by native proteinase gels.It was shown that the 65 kDa ATP-BPase is specifically induced by heat shock and not detectable in control cells.Its N-terminal 1-9 amino acid sequence was determined by Edman degradation, but no homologies to other proteins in the protein data bases were found. 30 and 31 kDa proteinases can be cleaved from the 45, 55 and 65 kDa proteinases to which they are linked. A possible relationship of the heat-induced 65 kDa ATP-BPase with the ATP-dependent proteinases (ATP-DPases) in prokaryotes and eukaryotes is discussed. | XU CUN SHUAN WEI MING ZHANG DIETER TECHEL MARCO MEYER YAN ZHANG LI LUDGER RENSING (Department of Biology, Henan Normal University,Xinxiang 453002)(Institute of Cell Biology, Bremen University, D-28359 Bremen, Germany) | 1999 | Cell Research1999，9，2： | 8 |
| 2 | Hepatitis B virus subgenotype F3 reactivation with vaccine escape mutations:A case report and review of the literature显示文摘Hepatitis B represents a global health threat because its chronic course and sequelae contribute to a high morbidity and mortality. Hepatitis B virus(HBV) infection can be controlled by vaccines, antiviral treatment, and by interrupting transmission. Rare vaccine escape mutants are serious because they eliminate vaccine protection. Here, we present a 74-year-old vaccinated patient with HBV reactivation 11 years after kidney transplantation. The patient was HBV-positive but HBs Ag-negative prior to vaccination 6 years before transplantation. The reactivated virus was HBV genotype F3 with vaccine escape mutations G145 R, P120 Q, and Q129 P. The patient was successfully treated with entecavir. The epidemiological reasons for this subgenotype, which is extremely rare in Western Europe, were unclear. This case illustrates that second-generation vaccines are not always effective in a specific group of patients. | Stefan Schlabe Kathrin van Bremen Souhaib Aldabbagh Dieter Glebe Corinna M Bremer Tobias Marsen Walter Mellin Veronica Di Cristanziano Anna M Eis-Hübinger Ulrich Spengler | 2018 | World Journal of Hepatology2018，10，7： | 2 |
| 3 | Mathematical modeling and control of population systems: applications in biological pest control 显示文摘 | RAFIKOV M BALTHAZAB J M VON BREMEN H F | 2008 | Applied Mathematics and Computation2008，200，2： | 1 |
| 4 | Classical hydraulic jump: sequent depths 显示文摘 | Hager W H Bremen R | 1989 | Journal of Hydraulic Research1989，，5： | 1 |
| 5 | Industrializing fiber lasers显示文摘 | Grupp M Seefeld T Vollertsen F BIAS Bremen Germany | 2004 | Ind Laser Solutions2004，3，： | 1 |
| 6 | Acidification and decline of central European forests 显示文摘 | | 1985 | Nature1985，315，： | 1 |
| 7 | An efficient and stable approach for computation of Lyapunov characteristic exponents of continuous dynamical systems显示文摘 | UDWADIA F E BREMEN H F | 2001 | Applied Mathematics and Computation2001，121，： | 1 |
| 8 | Selective laser melting显示文摘 | BREMEN S MEINERS W DIATLOV A | 2012 | Laser Teehnik Journal2012，9，2： | 1 |
| 9 | Impact of gastric emptying on levodopa pharmacokinetics in Parkinson dis- ease patients 显示文摘 | Muller T Erdmann C Bremen D | 2006 | Clin Neuropharmacol2006，29，2： | 1 |
| 10 | Efficiency of class Ⅱ dvision Ⅰ and class Ⅱ division 2 treatment in relation to different treatment approaches显示文摘 | Bremen JY Paneherz H | 2003 | Semin Orthod2003，9，： | 1 |
| 11 | Social Practices and the Management of Knowledge in Project Enviromments显示文摘 | Bremen M | 2003 | International Journal of Project Management2003，21，3： | 1 |
| 12 | Cooperative interception of neuronal apoptosis by BCL-2 and BAG-1expression: Prevention of caspase activation and reduced production of reactive oxygenspecies 显示文摘 | Schule JB Bremen D Reed JC Lommatzsch J Takayama S Wullner U Loschmann PA Klockgether T Weller M | 1997 | J Neurochem1997，69，8： | 1 |
| 13 | An efficient and stable approach for computation of Lyapunov characteristic exponents of continuous dynamicalsystems显示文摘 | UDWADIA F E BREMEN H F | 2001 | Applied Mathematics and Computation2001，121，23： | 1 |
| 14 | An efficient and stable approach for computation of Lyapunov characteristic exponents of continuous dynamical systems 显示文摘 | UdwadiaA F E Bremen H F | 2001 | Applied Mathematics and Computation2001，121，5： | 1 |
| 15 | Differential PI3K signal transduction in obesity-associated cardiac hypertrophy and response to ischemia显示文摘 | Uns?ld B Bremen E Didié M | 2015 | Obesity:SilverSpring2015，23，1： | 1 |
| 16 | Fuzzy Technology Implemented in Sonar Systerm显示文摘 | Kummert A GmbH A E Bremen | 1993 | IEEE Journal of Oceanic Engineering1993，18，4： | 1 |
| 17 | Efficiecy of early and late Class Ⅱ Division 1 treatment显示文摘 | Bremen JV Pancherz H | 2002 | Am J Orthod Dentofac Orthod2002，121，： | 1 |
| 18 | Cooperative interception of neuronal apoptosis by BCL - 2 and BAG - 1 expression : preven- tion of caspase activation and reduced production of reactive oxy- gen species显示文摘 | Schulz JB Bremen D Reed JC | 1997 | J Neurochem1997，69，5： | 1 |
| 19 | 有机硼化物离子渗硼显示文摘发展了以硼酸三甲脂B(OCH3)3为渗剂的离子渗硼工艺,并探讨了基体温度、处理时间以及气相中渗剂浓度对硼化铁层的影响。渗硼时间在1h以内可得到5μm厚的硼化铁层。一些处理参数会导致在硼化物层上形成硼-碳层,它将起着扩散垒的作用,阻止了硼化物进一步的生长。采用由渗硼剂加入和中断组成的工艺次序能防止该壁垒层的形成。初步的销-盘磨损试验结果表明,与未处理的钢基体相比离子渗硼减少了80%的磨损量。 | A. Kuper X. Qiao C. Jarms H R. Stock (Stiftung Institut fuer Werkstofftechnik Bremen Germany) | 1999 | 机械工程材料1999，23，4： | 1 |
| 20 | Is Herbst-muhibracket appli- ance treatment more efficient in adolescents than in adults? 显示文摘 | yon Bremen J Bock N Ruf S | 2009 | Angle Orthod2009，79，1： | 1 |
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