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| 1 | 赣南大吉山五里亭岩体的锆石ELA-ICP-MS定年及其与钨成矿关系的新认识显示文摘大吉山是南岭地区一个著名的大型钨多金属矿床,五里亭岩体是矿区出露规模最大的火成岩体,岩性为中粗粒似斑状黑云母二长花岗岩。锆石 ELA-ICP-MS 定年结果表明其形成年龄为 237.5±4.8 Ma,属印支期岩浆活动的产物。与南岭地区典型钨多金属矿床成矿岩体相比,五里亭岩体贫硅,富钙、镁、铁,Rb/Sr、Rb/Ba 和 U/Th 比值低,K/Rb 比值高,铕负异常不显著,分异指数低,尚未达到矿化岩体的分异演化程度,不具备矿化岩体的地球化学特征。元素—同位素综合示踪显示区内白云母碱长花岗岩为五里亭岩体经高度分异演化的产物,它与钨多金属矿成矿直接有关。矿区范围内出露的闪长岩起源于地幔,这一岩浆侵位所引起的高热场环境有利于花岗质岩石的形成与演化,对成矿具有重要的意义。 | 邱检生 McInnes BIA 徐夕生 Allen C M | 2004 | 地质论评2004，50，2： | 78 |
| 2 | 同位素年代学研究对江西会昌密坑山锡矿田成矿作用的启示显示文摘密坑山锡矿田是南岭地区与火山-次火山作用有关锡成矿的典型代表。本文运用锆石 U-Pb、全岩 Rb-Sr 和辉钼矿Re一()s同位素之年方法,对该区成岩和成矿年龄进行了系统测定,并据此讨论了它们的成矿意义:研究结果表明,密坑山岩体锆石 U-Pb 年龄为(136.0±1.7)Ma,全岩 Rb-Sr 等时线年龄(124.5±0.7)Ma,二个计时体系之间存在明显的时差,计算的冷却速率为8.7℃/Ma,指示岩体在成岩早期冷却相当缓慢。矿田范围内2件不同矿化类型辉钼矿的 Re-Os 模式年龄变化于(114.0±1.6)Ma 和(120.2±5 3)Ma 之间,它们均明显晚于成岩年龄,指示区内具有长时间的热液循环系统,成矿时间延续也较长,并可能经历了多期次的成矿作用区域动力地质背景和岩体地球化学特征的综合分析表明,密坑山矿田深部存在地幔物质的上涌,从而维系了高的地热场环境。这一高热场环境一方面使岩体缓慢冷却,同时也维系了长时间的热液循环系统,进而引发了大规模的锡成矿作用。 | 邱检生 蒋少涌 胡建 Mclnnes BIA 凌洪飞 | 2006 | 岩石学报2006，22，10： | 21 |
| 3 | Endoscopic submucosal dissection for the treatment of neoplastic lesions in the gastrointestinal tract显示文摘AIM: To investigate the indications, resection rate, and safety of endoscopic submucosal dissection (ESD) for neoplastic lesions in the gastrointestinal tract at a European referral center. METHODS: We carried out a retrospective analysis of the ESD procedures performed in our center for mucosal neoplastic and submucosal lesions of the gastrointestinal tract. The duration of the procedure, en bloc and complete (R0) resection rates, and complication rates were evaluated. Variables were reported as mean ± SD or simple proportions. Univariate analysis and comparisons of procedure times and resection rates were performed using Mann-Whitney U tests, or χ2 tests for dichotomous variables.RESULTS: Between 2007 and 2011, ESD was performed in a total of 103 patients (46.7% male, mean age 64.0 ± 12.7 years). The indications for the procedure were epithelial tumor (n = 54), submucosal tumor (n = 42), or other (n = 7). The total en bloc resection rate was 90.3% (93/103) and R0 resection rate 80.6% (83/103). The median speed of the procedure was 15.0 min/cm2 . The complete resection rate was lower for submucosal tumors arising from the muscle layer (68%, 15/22, P < 0.05). Resection speed was quicker for submucosal tumors localized in the submucosal layer than for lesions arising from the muscularis propria layer (8.1 min/cm 2 vs 17.9 min/cm 2 , P < 0.05). The R0 resection rate and speed were better in the last 24 mo (90.1%, 49/54 and 15.3 min/cm 2 ) compared to the first 3 years of treatment (73.5%, 36/49, P < 0.05 and 22.0 min/cm2 , P < 0.05). Complications occurred in 14.6% (n = 15) of patients, including perforation in 5.8% (n = 6), pneumoperitoneum in 3.9% (n = 4), delayed bleeding in 1.9% (n = 2), and other in 2.9% (n = 3). Only one patient with delayed perforation required surgical treatment. During the mean follow-up of 26 ± 15.3 mo, among patients with R0 resection, recurrence occurred in one patient (1.2%).CONCLUSION: ESD is an effective and safe method for resection of neoplastic lesions with low recurrence. Speed and the R0 resection rate increased after 50 procedures. | Andrzej Biaek Anna Wiechowska-Kozowska Jan Pertkiewicz Katarzyna Karpińska Wojciech Marlicz Piotr Milkiewicz Teresa Starzyńska | 2013 | World Journal of Gastroenterology2013，19，12： | 21 |
| 4 | Synchronous and metachronous neoplasms in gastric cancer patients:A 23-year study显示文摘AIM:To determine the prevalence and characteristics of additional primary malignancies in gastric cancer(GC)patients.METHODS:GC patients(862 total;570 men,292women;mean age 59.8±12.8 years)diagnosed at the Department of Gastroenterology at Pomeranian Medical University over a period of 23 years were included in this retrospective analysis of a prospectively maintained database.Mean follow-up time was 31.3±38.6 mo(range 1-241 mo).The following clinicopathological features of patients with synchronous tumors were compared to those with metachronous tumors:age,sex,symptom duration,family history of cancer,tumor site,stage(early vs advanced),histology,and blood group.GC patients with and without a second tumor were compared in terms of the same clinicopathological features.RESULTS:Of 862 GC patients,58(6.7%)developed a total of 62 multiple primary tumors,of which 39(63%)were metachronous and 23(37%)synchronous.Four(6.9%)of the 58 multiple GC patients developed two or more neoplasms.The predominant tumor type of the secondary neoplasms was colorectal(n=17),followed by lung(n=9),breast(n=8),and prostate(n=7).Age was the only clinicopathological feature that differed between GC patients with synchronous vs metachronous malignancies;GC patients with synchronous neoplasms were older than those with metachronous neoplasms(68.0±10.3 years vs 59.9±11.1years,respectively,P=0.008).Comparisons between patients with and without a second primary cancer revealed that the only statistically significant differences were in age and blood group.The mean age of the patients with multiple GC was higher than that of those without a second primary tumor(63.4±11.4years vs 59.5±13.0 years,respectively,P=0.026).GC patients with a second primary tumor were more commonly blood group O than those without(56.2%vs 31.6%,respectively,P=0.002).CONCLUSION:GC patients may develop other primary cancers;appropriate preoperative and postoperative diagnostic modalities are thus required,particularly if patients are older and blood group O. | Magorzata Lawniczak Alicja Gawin Halina Jaroszewicz-Heigelmann Wiesawa Rogoza-Mateja Joanna Raszeja-Wyszomirska Andrzej Biaek Katarzyna Karpińska-Kaczmarczyk Teresa Starzyńska | 2014 | World Journal of Gastroenterology2014，20，23： | 8 |
| 5 | Enamel microabrasion: An overview of clinical and scientific considerations显示文摘Superficial stains and irregularities of the enamelare generally what prompt patients to seek dental intervention to improve their smile. These stains or defects may be due to hypoplasia, amelogenesis imperfecta, mineralized white spots, or fluorosis, for which enamel microabrasion is primarily indicated. Enamel microabrasion involves the use of acidic and abrasive agents, such as with 37% phosphoric acid and pumice or 6% hydrochloric acid and silica, applied to the altered enamel surface with mechanical pressure from a rubber cup coupled to a rotatory mandrel of a lowrotation micromotor. If necessary, this treatment can be safely combined with bleaching for better esthetic results. Recent studies show that microabrasion is a conservative treatment when the enamel wear is minimal and clinically imperceptible. The most important factor contributing to the success of enamel microabrasion is the depth of the defect, as deeper, opaque stains, such as those resulting from hypoplasia, cannot be resolved with microabrasion, and require a restorative approach. Surface enamel alterations that result from microabrasion, such as roughness and microhardness, are easily restored by saliva. Clinical studies support the efficacy and longevity of this safe and minimally invasive treatment. The present article presents the clinical and scientific aspects concerning the microabrasion technique, and discusses the indications for and effects of the treatment, including recent works describing microscopic and clinical evaluations. | Núbia Inocencya Pavesi Pini Daniel Sundfeld-Neto Flavio Henrique Baggio Aguiar Renato Herman Sundfeld Luis Roberto Marcondes Martins José Roberto Lovadino Débora Alves Nunes Leite Lima | 2015 | World Journal of Clinical Cases2015，3，1： | 6 |
| 6 | Effects of protein deprivation and re-feeding on P2X_2 receptors in enteric neurons显示文摘AIM:To investigate the effects of malnutrition and refeeding on the P2X2 receptor,nitric oxide synthase(NOS),calretinin,calbindin and choline acetyltransferase(ChAT) in neurons of the rat ileum.METHODS:We analyzed the co-localization,numbers and sizes of P2X2-expressing neurons in relation to NOS-immunoreactive(IR),calbindin-IR,ChAT-IR,and calretinin-IR neurons of the myenteric and submucosal plexus.The experimental groups consisted of:(1) rats maintained on normal feed throughout pregnancy until 42 d post-parturition(N);(2) rats deprived of protein throughout pregnancy and 42 d post-parturition(D);and(3) rats undernourished for 21 d post-parturition and then given a protein diet from days 22 to 42(DR).The myenteric and submucosal plexuses were evaluated by double labeling by immunohistochemical methods for P2X2 receptor,NOS,ChAT,calbindin and calretinin.RESULTS:We found similar P2X2 receptor immunoreactivity in the cytoplasm and surface membranes of myenteric and submucosal neurons from the N,D and DR groups.Double labeling of the myenteric plexus demonstrated that approximately 100% of NOS-IR,calbindin-IR,calretinin-IR and ChAT-IR neurons in all groups also expressed the P2X2 receptor.In the submucosal plexus,the calretinin-IR,ChAT-IR and calbindin-IR neurons were nearly all immunoreactive for the P2X2 receptor.In the myenteric plexus,there was a 19% increase in numbers per cm2 for P2X2 receptor-IR neurons,64% for NOS-IR,84% for calretinin-IR and 26% for ChAT-IR neurons in the D group.The spatial density of calbindin-IR neurons,however,did not differ among the three groups.The submucosal neuronal density increased for calbindin-IR,calretinin-IR and ChAT-IR neurons.The average size of neurons in the myenteric plexus neurons in the D group was less than that in the controls and,in the re-fed rats;there was a 34% reduction in size only for the calretinin-IR neurons.CONCLUSION:This work demonstrates that expression of the P2X2 receptor is present in inhibitory,intrinsic primary afferent,cholinergic secretomotor and vasomotor neurons.Undernutrition affected P2X2 receptor expression in the submucosal plexus,and neuronal and size.These changes were rescued in the re-fed rats. | Rúbia Misawa Priscila Azevedo Girotti Márcia Sanae Mizuno Edson Aparecido Liberti John Barton Furness Patricia Castelucci | 2010 | World Journal of Gastroenterology2010，16，29： | 2 |
| 7 | Meta‐analysis: L actobacillus GG for treating acute gastroenteritis in children – updated analysis of randomised controlled trials显示文摘 | H. Szajewska A. Skórka M. Ruszczyński D. Gieruszczak‐Bia?ek | 2013 | Aliment Pharmacol Ther2013，，5： | 2 |
| 8 | Influence of mass-flow ratio of inner to outer secondary air on gas-particle flow near a swirl burner显示文摘The influence of mass-flow-rate ratio of inner to outer secondary air on gas-particle flow characteristics was determined in the near-burner region of a centrally fuel-rich swirl coal combustion burner.Velocity and particle volume flux profiles and normalized particle number concentrations were obtained.Peaks in tangential mean velocity and three-dimensional root-mean-square fluctuation velocities were found to decrease as the mass-flow-rate ratio increased.Moreover,the peaks in the mean axial velocities and particle volume flux near the wall increased,whereas those near the chamber axis decreased.Simultaneously,both recirculation zone and swirl number decreased as the mass-flow-rate ratio increased. | Jianping Jing Chunming Zhang Wei Suna Jieruo Ana Jinsheng Bia Zhengqi Lib | 2013 | Particuology2013，11，5： | 2 |
| 9 | Oxygen sensing and plant acclimation to soil flooding显示文摘 | Horchani F R'bia O Aschi-Smiti S | 2011 | Int J Agric Res2011，6，3： | 1 |
| 10 | Results of treatment of patients with gallstone disease and ductal calculi by single-stage laparoscopic cholecystectomy and bile duct exploration显示文摘 | Naumowicz E Bia覥ecki J Ko覥omecki K | 2014 | Wideochir Inne Tech Malo Inwazyjne2014，9，2： | 1 |
| 11 | Gitelman s variant of Bartter s syndrome, inherited hypokalaemie alkalosis, is caused by mutations in the hiazide-sensitive Na-C1 eotransporter显示文摘 | Simon D B Nelson-Williams C Bia M J | 1996 | Nat Genet1996，12，： | 1 |
| 12 | Enhanced infiammatory response to coronary angioplasty in patients with severe unstable angina显示文摘 | Liuzzo G Buffon A Bia S | 1998 | Circulation1998，32，3： | 1 |
| 13 | Contrast-enhancedUltrasound for Detect ion ofCrohn's Disease Activity:Systematic Review and Meta-analysis 显示文摘 | SerafinZ Bia?ecki M Bia?eckaA | 2015 | J Crohns Colitis2015，10，27： | 1 |
| 14 | Development and func- tion of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells 显示文摘 | ZI-IOU Z FRENCH D L biA G | 2010 | Stem Cells2010，28，3： | 1 |
| 15 | The effect of a bi-annual professional application of APF foam on dental caries increment in primary teeth:24 month clinical trial显示文摘 | Jiang H Bia NZ Tai BJ | 2005 | J Dent Res2005，84，3： | 1 |
| 16 | Evaluation of living re- nal donors the current practice of US transplant centers 显示文摘 | Bia M J Ramos EL Danovitch GM | 1995 | Transplantation1995，60，4： | 1 |
| 17 | Gitelman syn- drome revisited an evaluat ion of symptoms and health-related quality of life显示文摘 | Cruz D N S haer A J Bia M J | 2001 | Kidney Int2001，59，： | 1 |
| 18 | Cellular and computational studies of proteasome inhibition and apoptosis induction in human cancer cells by amino acid Schiff base-copper complexes 显示文摘 | Zuo J Bia CF Fana TH | 2013 | J Inorg Biochem2013，118，： | 1 |
| 19 | Treatment of cricopharyngeal dysfunction: a comparative pilot study 显示文摘 | Arenaz Bia B Olsson R Westin U | 2015 | BMC Res Notes2015，8，： | 1 |
| 20 | Changes in vein dynamics ranging from low to high pressure levels as a determinant of the differences in vein adaptation to arterial hemodynamic conditions 显示文摘 | Zocalo Y Daniel Bia Franco M | 2007 | Artif Organs2007，31，7： | 1 |
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