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| 1 | Associations of sense of coherence with psychological distress and quality of life in inflammatory bowel disease显示文摘AIM:To investigate the relationship between sense of coherence,psychological distress and health related quality of life in inflammatory bowel disease(IBD).METHODS:This cross-sectional study enrolled a consecutive sample of 147 IBD(aged 45.1 ± 14.1 years; 57.1% female) patients recruited from a tertiary gastroenterology service.Sixty-four participants met diagnostic criteria for Crohn's disease,while eightythree patients had ulcerative colitis.Socio-demographic data(education,age,race,gender,gross monthly income and marital status),disease-related variables(illness activity,relapse rate in past 2 years,history of surgery and time since diagnosis),sense of coherence(Antonovsky's SOC scale),psychological distress symptoms(Hospital Anxiety and Depression Scale) and health-related quality of life(HRQo L; WHOQOLBref) were assessed.Hierarchical multiple regression analyses were performed to identify factors that are independently associated with psychological distress and HRQo L in patients with IBD and to provide indications for possible moderating or mediating effects.In addition,formal moderation and mediation analyses(Sobel tests) were performed to confirm potential moderators/mediators of the relationship between SOC,psychological distress symptoms and HRQoL.RESULTS:Lower SOC scores(std beta=-0.504; P < 0.001),female gender(std beta = 0.176; P = 0.021) and White race(std beta = 0.164; P = 0.033) were independently associated with higher levels of depressive symptoms,while lower levels of SOC(std beta =-0.438; P < 0.001) and higher relapse rate(std beta = 0.161; P = 0.033) were independently associated with more severe anxiety symptoms.A significant interaction between time since diagnosis and SOC was found with regard to the severity of depressive or anxiety symptoms,as the interaction term(time since diagnosis X SOC) had beta coefficients of-0.191(P = 0.009) and-0.172(P = 0.026),respectively.Lower levels of anxiety symptoms(std beta =-0.369; P < 0.001),higher levels of SOC(std beta = 0.231; P = 0.016) and non-White race(std beta =-0.229; P = 0.006),i.e.,mixed-race,which represented the reference category,were independently associated with higher levels of overall HRQoL.Anxiety symptoms were the most potent independent correlate of most aspects of HRQoL.In addition,anxiety mediated the association between SOC and satisfaction with health,as well as its relationship with physical,mental,and social relations HRQo L.Depressive symptoms also mediated the association between SOC and mental HRQoL.CONCLUSION:Our data indicated that SOC is an important construct,as it influences psychological distress and has significant albeit indirect effects on several HRQoL domains in IBD. | Thiago H Freitas Elias Andreoulakis Gilberto S Alves Hesley LL Miranda Lúcia LBC Braga Thomas Hyphantis André F Carvalho | 2015 | World Journal of Gastroenterology2015，21，21： | 10 |
| 2 | Postoperative enteral versus parenteral nutrition in malnourished patients with gastrointestinal cancer: a randomised multicentre trial显示文摘 | F Bozzetti M Braga L Gianotti C Gavazzi L Mariani | 2001 | The Lancet2001，，9292： | 2 |
| 3 | Postoperative enteral versus parenteral nutrition in malnourished patients with gastrointestinal cancer:a randomized multicentre trial显示文摘 | Bozzetti F Braga M Gianotti L | 2001 | Lancet2001，358，9292： | 1 |
| 4 | Assessment of seed viability by laser speckle techniques 显示文摘 | Braga R A Dal Fabbro I M Borem F M | 2003 | Biosystems Engineering2003，86，3： | 1 |
| 5 | Sufentanil added to hyperbaric bupivacaine for subarachnoid block in Caesarean section显示文摘 | Braga Ade F Braga FS Pot6rio GM | 2003 | Eur J Anaesthesiol2003，20，8： | 1 |
| 6 | Postoperative enteral versus parenteral nutrition in malnourished patients with gastrointestinal cancer:a randomised multicentre trial显示文摘 | Bozzetti F Braga M Gianotti L | 2001 | Lancet2001，358，3： | 1 |
| 7 | Accuracy of 3D recon- structions based on cone beam computed tomography显示文摘 | Maret D Molinier F Braga J | 2010 | J Dent Res2010，89，12： | 1 |
| 8 | Sufentanil added to hyperbaric bupivachnoid for subarachnoid block in Caesarean section显示文摘 | Braga Ade F Braga FS Poterio GM | 2003 | Eur J Anaesthesiol2003，20，： | 1 |
| 9 | New processes for the production of solar-gradepolycrystalline silicon:A review显示文摘 | Braga A F B | 2008 | Solar Energy Materials&Solar Cells2008，92，： | 1 |
| 10 | Detection of fungi in beans by the laser biospeckle technique显示文摘 | Braga R A Rabelo G F Granato L R | 2005 | Biosystems Engineering2005，91，4： | 1 |
| 11 | Primary realignment vssuprapubic cystostomy for the management of pelvic frac- ture-associated urethral injuries: a systematic review and meta- analysis显示文摘 | Barrett K Braga L H Farrokhyar F | 2014 | Urology2014，83，4： | 1 |
| 12 | Postoperative enteral versus-parenteral nutriation in malnourished patients with gastrointestinal cancer : a randomized multicentre trial 显示文摘 | Bozzetti F Braga M Gianotti L | 2001 | Lancet2001，358，9292： | 1 |
| 13 | Composer-Science: a se- mantic service based framework for workflow composition in e-Sci- ence projects显示文摘 | da SILVA L M BRAGA R CAMPOS F | 2012 | Information Sciences2012，186，1： | 1 |
| 14 | In vitro predatory activity of nematophagous fungi and after passing through gastrointestinal tract of equine on infective larvae of Strongy- loides westeri显示文摘 | Araujo J M Araujo J V Braga F R | 2010 | Parasitol Res2010，107，1： | 1 |
| 15 | A checklist for critical appraisal of studies of biological variation显示文摘 | BARTLETT WA BRAGA F CAROBENE A | 2015 | Clin Chem Lab Med2015，53，6： | 1 |
| 16 | Obstruction of pipelines due to paraffin deposition during the flow of crude oils显示文摘 | Ribeiro F S Mendes P R S Braga S L | 1997 | International Journal of Heat Mass Transfer1997，18，1： | 1 |
| 17 | ^11C-methionine ( MET )and ^18F-FDG PET for the evaluation of suspected recurrent brain tumous(SRBT) 显示文摘 | Braga FJHN Flamen P Van Calenbergn F | 2000 | Eur J Nucl Med2000，27，8： | 1 |
| 18 | Turbulent heat transfer, pressure drop and fin efficiency in annular regions with continuous longitudinal rectangular fins 显示文摘 | BRAGA C V M SABOYA F E M | 1999 | Experimental Thermal Fluid Science1999，20，2： | 1 |
| 19 | In vitro predatory activity of conidia of fungal isolates of the Duddingtonia fla grans on Angiostrongylus vasorum first-stage larvae显示文摘 | Braga F R Araujo J M Araujo J V | 2013 | Rev Soc Bras Med Trop2013，46，1： | 1 |
| 20 | An anatomical study of the dorsal cutaneous branches of the digital arteries显示文摘 | Braga SJ Kuyven CR Fallopa F | 2002 | J Hand Surg2002，27，： | 1 |
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