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| 1 | Research advances on the multiple uses of Moringa oleifera: a sustainable alternative for socially neglected population显示文摘Moringa oleifera Lam(Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. Moreover, M. oleifera seeds are widely used in water and effluent treatment, for their coagulation, flocculation and sedimentation properties, their ability of improving water quality, by reducing organic matter and microbial load, with special applicability in intensive animal production systems, such as aquaculture. In addition, due to its high nutritional value and several medicinal properties, this tree may act as a nutritional and medical alternative for socially neglected populations. In this context, this review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects. | Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Vandbergue Santos Pereira Débora de Souza Collares Maia Castelo-Branco Rossana de Aguiar Cordeiro Célia Maria de Souza Sampaio Manoel de Araújo Neto Paiva Joao Bosco Feitosa dos Santos JoséJúlio CostaSidrim Marcos Fábio Gadelha Rocha | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，7： | 10 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | RFLP discordance in a PKUfamily due to a deletion in the PAH gene 显示文摘 | Bosco P Ceratto N Cali F | 1996 | Turk J Pediatr1996，38，4： | 1 |
| 4 | Hypoxic synovial environment and expression of macrophage inflammatory protein 3gamma/ CCL20 in juvenile idiopathic arthritis 显示文摘 | Bosco MC Delfino S Ferlito F | 2008 | Arthritis Rheum2008，58，6： | 1 |
| 5 | The risk of relapse after a clinically isolated syndrome is related to the pattern of oligoclonal bands显示文摘 | Bosco I Magraner MJ Coret F | 2010 | J Neuroimmunol2010，226，112： | 1 |
| 6 | A posteriori error estimates for fully discrete nonlinear parabolic problems显示文摘 | Javier F Bosco G A Julia N | 2007 | Comput Methods Appl Mech Engrg2007，196，： | 1 |
| 7 | Effect of thalidomide and rosiglitazone on the prevention of diabetic retinopathy in streptozotocin-induced diabetic rats显示文摘 | Bosco A A Lerario A C Santos R F | 2003 | Diabetologia2003，46，12： | 1 |
| 8 | Neurokinin 1 receptor expression and substance P physiological actions are developmentally regulated in the rabbit retina显示文摘 | Casini G Dal Monte M Fornai F Bosco L Willems D Yang Q | 2004 | Neuroscience2004，124，1： | 1 |
| 9 | Posterior lumbar fusion by peek rods in degenerative spine preliminary report on 30 cases显示文摘 | F De Iure G Bosco M Cappuccio | 2012 | EurSpineJ2012，，1： | 1 |
| 10 | A Nationwide Comparison of Driving Distance Versus Straight-Line Distance to Hospitals显示文摘 | Boscoe F P Henry K A Zdeb M S | 2012 | The Professional Geographer2012，64，20： | 1 |
| 11 | Protective glass coating for carbon-carbon composites显示文摘 | Isola C Appendino P Bosco F | 1998 | Carbon1998，36，78： | 1 |
| 12 | Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory pheno- type and TREM-1 expression显示文摘 | Pierobon D Bosco MC Blengio F | 2013 | Eur J Immunol2013，43，4： | 1 |
| 13 | Elevated thrombopoietin in plasma of burned patients without and with sepsis enhances platelet activation显示文摘 | Lupia E Bosco O Mariano F | | 0，，06： | 1 |
| 14 | RB signaling prevents replicationdependent DNA double-strand breaks following genotoxic insult显示文摘 | BOSCO E E MAYHEW C N HENNIGAN R F | 2004 | Nucleic Acids Res2004，32，： | 1 |
| 15 | Use of progestagen-gonadotrophin treatments in estrus synchronization of sheep 显示文摘 | Boscos C M Samartzi F C Dellis S | 2002 | Theriogenology2002，58，7： | 1 |
| 16 | Impact of integrin matrix matching and inhibition of apoptosis on the survival of purified human beta-cells in vitro显示文摘 | Ris F Hammar E Bosco D | 2002 | Diabetologia2002，45，： | 1 |
| 17 | Endoscopic thoracic sympathecotomy for the treatment of complex regional pain syndrome 显示文摘 | Bosco V D J Kux P Duarte D F | 2003 | Clin Auton Res2003，13，1： | 1 |
| 18 | Development of a rapid LC - DAD/FLD method for the simultaneous determination of auxins and absclsic acid in plant extracts显示文摘 | Bosco R Caser M Vanara F | 2013 | Journal of Agricultural and Food Chemistry2013，61，10： | 1 |
| 19 | Spectral decomposition of expanding probabilistic dynamical systems显示文摘 | Antoniou I Bosco F Suchanecki Z | 1998 | Plays Lett A1998，239，： | 1 |
| 20 | Patient self-appraisal of change and minimal clinically important, difference on the European organization for the research and treatment of cancer quality of life questionnaire core 30 before and during cancer therapy显示文摘 | Hong F Bosco JL Bush N | 2013 | BMC Cancer2013，13，： | 1 |
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