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65篇 您的检索式:作者名="BOSCH R W"
    题名 作者 年代 出处 被引量
1Application of electrochemical impedance spectroscopy for monitoring stress corrosion cracking显示文摘BOSCH R W MOONS F ZHENG J H BOGAERTS W F 2001Corrosion2001,57,6:1
2High yield secretion of recombinant gelatins by Pichia Pastoris显示文摘Werten M W Vande Bosch T J Wind R D 1999Yeast1999,15,11:1
3Electrochemical impedance spectroscopy for the detection of stress corrosion cracks in aqueous corrosion systems at ambient and high temperature显示文摘BOSCH R W 2005Corros Sci2005,47,1:1
4Electrochemical frequency modulation: a new electrochemical technique for online corrosion monitoring 显示文摘Bosch R W Hubrecht J Bogaerts W F 2001Corrosion2001,57,:1
5Thermal processing of whole soya beans: Studies on the inactivation of antinutritional factors and effects on ileal digestibility in piglets显示文摘Qin G Ter Elst E R Bosch M W 1996Anita Feed Sci Tech1996,57,:1
6Prospective clinical evaluation of an electronic portal imaging device显示文摘Michalski J M Graham M V Bosch W R et ol 1996Int J Radiat Biol Phys1996,34,4:1
7Highyield zecretion of recombinant gelatins by Pichia pastoris显示文摘Werten M W T T J Van den Bosch Wind R D 1999Yeast1999,15,11:1
8Prenatal stress increases HPA axis activity and impairs maternal care in lactating female offspring:implications for postpartum mood disorder显示文摘Bosch OJ Müsch W Bredewold R 2007Psychoneuroendocrinology2007,32,3:1
9Simple mathematical models for cannibalism: a critique and a new approach显示文摘Diekmann O Nisbet R M Gurney W S C F vanden Bosch 1986Math Biosci1986,78,:1
10Human imrmunodeficiency virus Type 1 nucleoeapsid Zn^2+ fingers are required for effi-cient reverse transcription,initial integration processes,and protection of newly synthesized viral DNA显示文摘BUCKMAN J S BOSCHE W J GORELICK R J 2003J Virol2003,77,:1
11Liquid chromatographytandem mass spectrometric assay for the analysis of uracil, 5, 6- dihydrouracil and beta-ureidopropionic acid in urine for the measurement of the activities of the pyrimidine catabolic enzymes 显示文摘Sparidans R W Bosch T M Jorger M 2006J Chromatogr B Analyt Technol Biomed Life Sci2006,839,12:1
12AGNPS: A non-point-source pollution model for evaluating agricultural water- sheds显示文摘Young R A Onstad C A Bosch D D Anderson W P 1989Jornal of Soil and Water Conservation1989,44,2:1
13The role of management innovation in enabling technological process innova- tion: An inter- organizational perspective 显示文摘HOLLEN R VAN DEN BOSCH F A J VOLBERDA H W 2013European Manage- ment Review2013,10,1:1
14Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the middle east respiratory syndrome coronavirus显示文摘Rai V S Stairs S L Provaeia L B van den Brand J M Wiersma L Ouwendijk W J Bestebroer T M Spronken M I van Amerongen G Rottier P J Foueh- ier R A Bosch B J Osterhaus A D Haagmans B L 2014J Virol2014,88,18:1
15Thermal processing of whole soya beans : studies on the inactivation of antinutritional factors and effects on ileal digestibility in piglets显示文摘Qin G ter Elst E R Bosch M W 1996Anim Feed Sci Technol1996,57,:1
16Electrochemical impedance spectroscopy for the detection of stress corrosion cracks in aqueous corrosion system at ambient and high temperature显示文摘R W Bosch 2005Corrosion Science2005,47,1:1
17High-yield secretion of recombinant gelatins by Pichia pastoris 显示文摘WERTEN M W T VAN DEN BOSCH T J WIND R D 1999Yeast1999,15,:1
18人乳头瘤病毒16/18型AS04佐剂疫苗预防肿瘤基因型HPV引起的宫颈感染和癌前病变的效应(PATRICIA):一项在年轻女性中进行的双盲、随机研究的最终分析显示文摘背景在年轻成人中进行的Ⅲ期随机、双盲对照PATRICIA试验(PApilloma TRial)的事件驱动期中分析显示,人乳头瘤病毒(HPV)16/18AS04佐剂疫苗具有免疫原性,且总体耐受性良好,对HPV16或HPV18感染及相关的癌前病变具有预防效应。本文作者旨在评估最终事件驱动分析中的疫苗效应。方法将在基线、1个月和6个月接种疫苗的15~25岁女性分类为符合方案的效应队列(ATP-E队列;疫苗组8093例,对照组8069例)、总接种队列(TVC;包括至少接种1剂疫苗的所有女性,而不考虑其基线HPV状态;代表普遍的年轻女性人群,包括性活跃者;疫苗组9319例,对照组9325例)和TVC-naive(无证据表明基线时存在肿瘤基因型HPV感染;代表无性行为女性;疫苗组5822例,对照组5819例)。主要终点是。在基线时血清和DNA均为阴性且在6个月时为相应类型(ATP-E队列)的女性中,评估疫苗对HPV16或HPV18相关性宫颈上皮内瘤变≥2级(CIN2+)的预防效应。该试验在ClinicalTrial.gov上的注册编码为NCT00122681.结果第3剂疫苗接种后平均随访34.9个月(s=6.4)。在主要分析中疫苗对HPV16/18相关性CIN2+的预防效应为92.9%(96.1%CI79.9%~98.3%),在对可能因多种肿瘤基因型HPV引起的病变(ATP-E队列)的分析中,其预防效应为98.1%(96.1%CI88.4%~100%)。不考虑病变HPVDNA时,疫苗对CIN2+的预防效应在TVC中为30.4%(96.1%CI16.4%~42.1%),在TVC-naive中为70.2%(96.1%CI54.7%~80.9%);而对CIN3+的相应效应在TVC中为33.4%(96.1%CI9.1%~51.5%).在TVC-naive中为87.0%(96.1%CI54.9%~97.7%).在预防12种非疫苗肿瘤基因型HPv相关性CIN2+的效应为54.0%(96.1%CI34.0%~68.4%:ATP-E队列)。在TVC中可见对HPV31、33和45相关性CIN2+的个体交叉保护效应。结论HPV16/18 AS04佐剂疫苗表现出对HPV16/18和非疫苗肿瘤基因型HPV相关性CIN2+较强的预防效应,而要获得整体预防效应就需要在更广泛的人群中进行大面积强化免疫计划。基金 葛兰素史克。J Paavonen P Naud J Salmeron C M Wheeler S-N Chow D Apter H Kitchener X Castellsague J C Teixeira S R Skinner J Hedrick U Jaisamrarn G Limson S Garland A Szarewski B Romanowski F Y Aoki T F Schwarz W A J Poppe F X Bosch D Jenkins K Hardt T Zahaf D Descamps F Struyf M Lehtinen G Dubin 周彩虹(译) 2009世界临床医学2009,,12:1
19Preparation and characterization of differently aggregated colorectal carcinoma cell subpopulations from surgical specimens 显示文摘Bosch J Brossmer R Kemmner W 1998Cancer Detect Prev1998,22,4:1
20High yield secretion of recombinant gelatins by Pichia Pastoris显示文摘Werten M W Vande Bosch T J Wind R D 1999Yeast1999,15,11:1
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