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| 1 | Liver bioengineering:Current status and future perspectives显示文摘The present review aims to illustrate the strategies that are being implemented to regenerate or bioengineer livers for clinical purposes.There are two general pathways to liver bioengineering and regeneration.The first consists of creating a supporting scaffold,either synthetically or by decellularization of human or animal organs,and seeding cells on the scaffold,where they will mature either in bioreactors or in vivo.This strategy seems to offer the quickest route to clinical translation,as demonstrated by the development of liver organoids from rodent livers which were repopulated with organ specific cells of animal and/or human origin.Liver bioengineering has potential for transplantation and for toxicity testing during preclinical drug development.The second possibility is to induce liver regeneration of dead or resected tissue by manipulating cell pathways.In fact,it is well known that the liver has peculiar regenerative potential which allows hepatocyte hyperplasia after amputation of liver volume.Infusion of autologous bone marrow cells,which aids in liver regeneration,into patients was shown to be safe and to improve their clinical condition,but the specific cells responsible for liver regeneration have not yet been determined and the underlying mechanisms remain largely unknown.A complete understanding of the cell pathways and dynamics and of the functioning of liver stem cell niche is necessary for the clinical translation of regenerative medicine strategies.As well,it will be crucial to elucidate the mechanisms through which cells interact with the extracellular matrix,and how this latter supports and drives cell fate. | Christopher Booth Tom Soker Pedro Baptista Christina L Ross Shay Soker Umar Farooq Robert J Stratta Giuseppe Orlando | 2012 | World Journal of Gastroenterology2012，18，47： | 2 |
| 2 | A novel means of self-protection, unrelated to toxinactivation, cofers immunity to bactericidal effects of the Enterococcus cytolysin显示文摘 | Cobum P S Hancock L E Booth M C | 1999 | Infect Immun1999，67，7： | 1 |
| 3 | Capital Raising,Un-derwriting and the Certification Hypothesis显示文摘 | Booth J. R Smith R. L | | 0，，1： | 1 |
| 4 | Human plasma carotenoid response to the ingestion of controlled diets high in fruits and vegetables显示文摘 | YEUM K J BOOTH S L SADOWSKI J A | 1996 | Am J Clini Nutr1996，64，4： | 1 |
| 5 | Screening for asymptomtic deep vein thrombosis in surgical intensive care patients显示文摘 | Harris L M Curl G R Booth F V | 1997 | J Vasc Surg1997，26，6： | 1 |
| 6 | Photopolymer Material for Holography 显示文摘 | BOOTH B L | 1975 | Applied Optics(S0003-6935)1975，14，3： | 1 |
| 7 | Development of Numerical Estimation in Young Children 显示文摘 | Siegler R S Booth J L | 2004 | Child Development2004，，75： | 1 |
| 8 | The Distribution and Origin of Trace Elements in a UK Coal:the Importance of Pyrite显示文摘 | Spears D A Manzanares Papayanopous L I Booth C A | 1999 | Fuel1999，78，14： | 1 |
| 9 | Development of numerical estimation in young children 显示文摘 | Siegler R S & Booth J L | 2004 | Child Development2004，75，： | 1 |
| 10 | A comparative study of the characteristics of fibre-flax (Linum usitatissimum)显示文摘 | Booth I Harwood R J Wyatt J L | 2004 | Industrial Crops and Products2004，20，1： | 1 |
| 11 | Continuum percolation and geometry of wireless networks显示文摘 | BOOTH L BRUCK J FRANCESCHETTI M | 2003 | Annals of Applied Probability2003，13，2： | 1 |
| 12 | Low loss channel waveguides in polymers显示文摘 | Booth B L | 1989 | J Lightwave Technol1989，7，： | 1 |
| 13 | Clinical features and short-term outcomes of 144 patients with SARS in the greater toronto area显示文摘 | Booth C M Matukas L M Tomlinson G A | 2003 | JAMA2003，289，： | 1 |
| 14 | The distribution and origin of trace elements in a UK coal: The importance of pyrite 显示文摘 | Spears D A Manzanares- Papayanopoulos L I Booth C A | 1999 | Fuel1999，78，14： | 1 |
| 15 | Graphene-based liquid crystal device 显示文摘 | BLAKE P BRIMICOMBE P D NAIR R R BOOTH T J JIANG D SCHEDIN F PONOMARENKO L A MOROZOV S V GLEESON H F HILL E W GEIM A K NOVOSELOV K S | 2008 | Nano Letters2008，8，6： | 1 |
| 16 | The classical progesterone receptor mediates Xenopus oocyte matu- ration through a nongenomic mechanism 显示文摘 | Bayaa M Booth R A Sheng Y L | 2000 | Proceed- ings of the National Academy of Sciences2000，97，12： | 1 |
| 17 | Capital structures in developing countries显示文摘 | Booth L Aivazian V Demirguc-Kunt A Maksimovic V | 2001 | Journal of Finance2001，56，1： | 1 |
| 18 | HDAC inhibitors enhance the lethality of low dose salinomycin in parental and stem-like GBM cells显示文摘 | BOOTH L ROBERTS J L CONLEY A | 2014 | Cancer Biol Ther2014，15，3： | 1 |
| 19 | Promoting physical activity participation among children and adolescents显示文摘 | Salmon J Booth M L Phongsavan P | 2007 | Epidem Rev2007，29，1： | 1 |
| 20 | Capital Raising, Underwriting and the Certification Hypothesis 显示文摘 | Booth James R Richard L Smith | 1986 | Journal of Financial Economics1986，15，12： | 1 |
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