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37篇 您的检索式：作者名="BOLLO"

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	题名	作者	年代	出处	被引量
1	肿瘤恶性转化与C/EBPβ和STAT3基因相关(英文)显示文摘The inference of transcriptional networks that regulate transitions into physiological or pathological cellular states remains a central challenge in systems biology. A mesenchymal phenotype is the hallmark of tumour aggressiveness in human malignant glioma,but the regulatory programs responsible for implementing the associated molecular signature are largely unknown. Here we show that reverse-engineering and an unbiased interrogation of a glioma-specific regulatory network reveal the transcriptional module that activates expression of mesenchymal genes in malignant glioma. Two transcription factors (C/EBPβ and STAT3) emerge as synergistic initiators and master regulators of mesenchymal transformation. Ectopic co-expression of C/EBPβ and STAT3 reprograms neural stem cells along the aberrant mesenchymal lineage,whereas elimination of the two factors in glioma cells leads to collapse of the mesenchymal signature and reduces tumour aggressiveness. In human glioma,expression of C/EBPβ and STAT3 correlates with mesenchymal differentiation and predicts poor clinical outcome. These results show that the activation of a small regulatory module is necessary and sufficient to initiate and maintain an aberrant phenotypic state in cancer cells.	Maria Stella Carro Wei Keat Lim Mariano Javier Alvarez Robert J. Bollo Evan Y. Snyder Erik P. Sulman Sandrine L. Anne Fiona Doetsch Howard Colman Anna Lasorella Ken Aldape Andrea Califano Antonio Iavarone	2010	中华神经外科疾病研究杂志2010，9，1：	16
2	Scanning electron microscopy of pathologic changesin the epithelial surface of unterus and uterine tubes of cow显示文摘	Bollo E Biolatti B Galloni M	1990	Am J Vet Res1990，51，1：	2
3	Ultratrace measurements of nucleic acids by baseline-corrected adsorptive stripping square-wave voltammetry显示文摘	WANG J BOLLO S	1999	Anal Chem1999，71，：	1
4	Electrochemical reduction of nitrotetralones显示文摘	SQUELLA J A HUERTA M BOLLO S	1997	Journal of Electroanalytical Chemistry1997，420，12：	1
5	Strategic management of a transformation in a multi-program technology program involving convergence and divergence of programs: Observations from NASA 显示文摘	Kotnour T Bollo T R	2011	International Journal of Technology Management2011，53，24：	1
6	J Electroanal Chem显示文摘	Bollo S Soto-Bustamante E	2000	492:542000，492，：	1
7	Study of a new design of an incre mental optical encoder 显示文摘	LUTENBERG A PEREZ QUINTIAN F RE BOLLO M A	2006	SPIE2006，6292，：	1
8	Detection of Mycobacterium tuberculosis complex in lymph nodes of wild boar(Sus scrofa) by a target-Amplified Test System显示文摘	Bollo E Ferroglio E Dini V	2001	J Vet Med Series B2001，47，5：	1
9	Isolation of Brucella melitensis from alpine ibex显示文摘	Ferroglio E Tolari F Bollo E	1998	J Wild Dis1998，34，：	1
10	Scanning electron microscopy of pathologic changes in the epithelial surface of the uterus and uterine tubes of cow显示文摘	Bollo E Biolatti B Galloni M	1990	Am J Vet Res1990，51，1：	1
11	Electroreduction of 4-(nitrophenyl) substituted 1,4-dihydropyridines on the mercury electrode in aprotic medium显示文摘	SQUELLA J A JIMENEZ G BOLLO S	1997	Electrochimica Acta1997，42，15：	1
12	Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs显示文摘	Bollo M Paredes RM Holstein D	2010	PLoS One2010，5，11：	1
13	Electrochemical generation and interaction study of nitro radical anion from nimesulide 显示文摘	Squella JA Gonzalez P Bollo S	1999	Pharm Res1999，16，1：	1
14	Guidelines for the diagnosis and treatment of idiopathic pulmonary fibrosis 显示文摘	Antoni Xaubet Julio Ancochea Elena Bollo	2013	Archivos de Bronconeumologia ( English Edition )2013，49，8：	1
15	Ultratrace measurements of nucleic acids by baseline corrected adsorptive stripping square-wave voltammeter显示文摘	WANG J BOLLO S LOPEZ PAZ J L SAHLIN E MUKHER JEE B	1999	Anal Chem1999，71，9：	1
16	Antioxidant capacity as a reliable marker of stress in dairy calves transported by road显示文摘	Pregel P Bollo E Cannizzo F	2005	Veterinary Record2005，156，2：	1
17	Electrooxidation of DNA at glassy carbon electrodes modified with multiwall carbon nanotubes dispersed in chitosan显示文摘	BOLLO S FERREYRA N F RIVAS G A	2007	Electroanalysis2007，19，7：	1
18	Complex Chiari malformations in children: an analysis of preoperative risk factors for occipitocervical fusion 显示文摘	Bollo R J Riva Cambrin J Brockmeyer MM	2012	J Neurosurg Pediatr2012，10，2：	1
19	Biochemical, ultrastructural and molecular characterization of the triphenyltin acetate (TPTA) -induced apoptosis in primary culturesof mouse thymocytes显示文摘	Bollo E Guglielmino R Sant S	2006	Cell Biol Toxicol2006，22，：	1
20	Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs显示文摘	Bollo M Paredes R M Holstein D	2010	PLoS One2010，5，11：	1

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