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| 1 | Development of an internally braced prosthesis for total talus replacement显示文摘Total loss of talus due to trauma or avascular necrosis,for example,still remains to be a major challenge in foot and ankle surgery with severely limited treatment options.Implantation of a custom made total talar prosthesis has shown promising results so far.Most important factors for long time success are degree of congruence of articular surfaces and ligamentous stability of the ankle.Therefore,our aim was to develop an optimized custom made prosthesis for total talus replacement providing a high level of primary stability.A custom made hemiprosthesis was developed using computed tomography and magnetic resonance imaging data of the affected and contralateral talus considering the principles and technology for the development of the S.T.A.R.prosthesis(Stryker).Additionally,four eyelets for fixation of artificial ligaments were added at the correspondent footprints of the most important ligaments.Two modifications can be provided according to the clinical requirements:A tri-articular hemiprosthesis or a bi-articular hemiprosthesis combined with the tibial component of the S.T.A.R.total ankle replacement system.A feasibility study was performed using a fresh frozen human cadaver.Maximum range of motion of the ankle was measured and ligamentous stability was evaluated by use of standard X-rays after application of varus,valgus or sagittal stress with 150 N.Correct implantation of the prosthesis was technically possible via an anterior approach to the ankle and using standard instruments.Malleolar osteotomies were not required.Maximum ankle dorsiflexion and plantarflexion were measured as 22-0-28 degrees.Maximum anterior displacement of the talus was 6 mm,maximum varus tilt 3 degrees and maximum valgus tilt 2 degrees.Application of an internally braced prosthesis for total talus replacement in humans is technically feasible and might be a reasonable procedure in carefully selected cases with no better alternatives left. | Markus Regauer Mirjam Lange Kevin Soldan Steffen Peyerl Sebastian Baumbach Wolfgang Bocker Hans Polzer | 2017 | World Journal of Orthopedics2017，8，3： | 4 |
| 2 | Promoting axonal regeneration following nerve surgery: a perspective on ultrasound treatment for nerve injuries显示文摘Nerve injury is often associated with limited axonal regeneration and thus leads to delayed or incomplete axonal reinnervation.As a consequence of slow nerve regeneration,target muscle function is often insufficient and leads to a lifelong burden.Recently,the diagnosis of nerve injuries has been improved and likewise surgical reconstruction has undergone significant developments.However,the problem of slow nerve regeneration has not been solved.In a recent meta-analysis,we have shown that the application of low-intensity ultrasound promotes nerve regeneration experimentally and thereby can improve functional outcomes.Here we want to demonstrate the experimental effect of low intensity ultrasound on nerve regeneration,the current state of investigations and its possible future clinical applications. | Konstantin D. Bergmeister Simeon C. Daeschler Patrick Rhodius Philipp Schoenle Arne Bocker Ulrich Kneser Leila Harhaus | 2018 | Neural Regeneration Research2018，13，9： | 3 |
| 3 | Usual ductal hyperplasia of the breast is a committed stem/progenitor cell lesion distinct from atypical ductal hyperplasia and ductal carcinoma in-situ显示文摘 | Bocker W Moll R Dervan P | 2002 | J Pathol2002，198，4： | 1 |
| 4 | Vascular smooth muscle and nitric oxide synthase显示文摘 | Buehwalow IB Podzuweit T Bocker W | 2002 | FASEB J2002，16，6： | 1 |
| 5 | Rapid unbiased bipolar incoherent calculator cube 显示文摘 | Bocker R P Caulfield H J Bromley K | 1982 | Appl Opt1982，22，6： | 1 |
| 6 | Rapid expression of the CD69 antigen on T cells and natural killer upon antigenic stimulation of peripheral blood mononuclear cell suspensions 显示文摘 | Werfell T Bocker M Kapp A | 1997 | Allergy1997，52，4： | 1 |
| 7 | Photonic comput- ing using the modified signed-digit number representation显示文摘 | Draker B L Bocker R P Lasher M E | 1986 | Optical Engineering1986，25，： | 1 |
| 8 | Some effects of non-surgical therapy on gingival inflammatory cell subsets in patients with adult and early-onset periodontitis显示文摘 | KLEINFELDER JW LANGE DE BOCKER W | 2000 | J Periodontol2000，71，10： | 1 |
| 9 | Synthesis and properties for nonionic surfactants显示文摘 | BOCKER T THIEM J | 1989 | Tenside Surf Det1989，26，5： | 1 |
| 10 | Influence of Glucose Concentration on Light Scattering in Tissue Simulation Phantom 显示文摘 | KOHL M ESSENPREIS M BOCKER D | 1994 | Optics Letters1994，19，24： | 1 |
| 11 | Role of the venous system in hemodynamics during ultrafihration and bicarbonate dialysis 显示文摘 | Kooman JP Gladziwa U Bocker G | 1992 | Kidney Int1992，42，3： | 1 |
| 12 | Implantation of cardiac resynchronization therapy systems in the CARE-HF trial: procedural success rate and safety 显示文摘 | Gras D Bocker D Lunati M | 2007 | Europace2007，9，7： | 1 |
| 13 | Diagnosis microsatellite instability: definition and correlation with mismatch repair protein expression显示文摘 | Wallinger S Bocker T | 1997 | Cancer Res1997，57，21： | 1 |
| 14 | Implantation of cardiac resynchronization therapy systems in the care-HF trial : procedural success rate and safety 显示文摘 | Gras D Bocker D Lunati M | 2007 | Europace2007，9，7： | 1 |
| 15 | Genomic analysis reveals Lactobacillus sanfranciscensis as stable element in traditional sourdoughs 显示文摘 | Vogel RF Pavlovic M Ehrmann MA Wiezer A Liesegang H Offschanka S Voget S Angelov A Bocker G Liebl W | 2011 | Microb Cell Fact2011，10，1： | 1 |
| 16 | WHO classification of breast tumors and tumors of the female genital organs: pathology and genetics 显示文摘 | Bocker W | 2002 | Verh Dtsch Ges Pathol2002，86，： | 1 |
| 17 | Diagnostic value of different PCR assays for the detection of mycobacterial DNA in granulom atous lymphadenopathy显示文摘 | Bocker W Brommelkamp E | 1996 | J Pathol1996，178，2： | 1 |
| 18 | Microsatellite instability analysis:a multicenter study for reliability and quality control显示文摘 | Bocker T Diermann J Friedl W | 1997 | Cancer Res1997，57，21： | 1 |
| 19 | Non-invasive estimation of cardiac output in critical care patients显示文摘 | Gerhardt UM Scholler C Bocker D | 2000 | J Clin Monit Comput2000，16，4： | 1 |
| 20 | Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages:A new cell biological concept显示文摘 | Bocker W Moll R Poremba C | 2002 | Lab Invest2002，82，6： | 1 |
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