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| 1 | 自发性脑出血管理指南 美国心脏协会/美国卒中协会针对医疗专业人员的指南显示文摘目的本指南旨在为自发性脑出血的诊断和治疗提供最新的全面推荐意见。方法利用PubMed进行规范化文献检索,检索时间至2013年8月底。撰写委员会成员通过远程电信会议讨论指南内容及推荐意见,采用美国心脏协会/美国卒中协会的疗效确定性水平和证据分级方案对推荐意见进行分级。由6位同行评议专家以及卒中委员会科学声明监督委员会和卒中委员会领导委员会成员对指南草案进行发表前审阅。结果本文为急性脑出血患者的医疗诊治提供了循证指南,重点包括诊断、凝血功能障碍和血压管理、继发性脑损伤防治、颅内压控制、外科治疗的作用、转归预测、康复、二级预防以及将来需要考虑的问题。本指南已纳入最新的3期临床试验结果。结论脑出血是一种需要进行早期积极救治的危重疾病。本指南为脑出血患者的目标导向治疗提供了一个框架。 | J. Claude Hemphill Ⅲ Steven M. Greenberg Craig S. Anderson Kyra Beckelr Bernard R. Bendok Mary Cushman Gordon L. Fung Joshua N. Goldstein R. LochMacdonald Pamela H Mitchell, Phillip A Scott,Magdy H Selim, Daniel Woo 高圆圆 徐欣 | 2015 | 国际脑血管病杂志2015，23，10： | 444 |
| 2 | 采用不同湍流模型及差分格式对四角切向燃烧煤粉锅炉内冷态流场的数值模拟显示文摘采用商业软件 FLUENT所提供的不同湍流模型 ;K-ε模型、RNG K-ε模型、带旋流修正的 RNG K-ε模型、Realizable K-ε模型、雷诺应力模型 ,对四角切向燃烧煤粉锅炉内冷态气相流动进行了数值模拟。为减小数值伪扩散对强旋流动的影响 ,本文采用了减小网格尺寸和提高差分格式精度等措施。通过与实验结果的对比分析 ,客观评价了这些模型与方法对该流动模拟效果的影响 ,为理论分析强旋湍流流动和对四角切向燃烧煤粉锅炉内流体流动的工程设计提供了参考依据。图 5参 | 由长福 祁海鹰 徐旭常 Bernard Baudoin | 2001 | 动力工程2001，21，2： | 45 |
| 3 | 植物促生菌及其促生机理(续)显示文摘 | 黄晓东 季尚宁 Bernard Glick Bruce Greenberg 卢林纲 | 2002 | 现代化农业2002，，7： | 48 |
| 4 | Quantitative analysis using ELISA of vascular endothelial growth factor and basic fibroblast growth factor in human colorectal cancer,liver metastasis of colorectal cancer and hepatocellular carcinoma显示文摘TO THE EDITOR Angiogenesis consists of the sprouting of capillaries from pre-existing vessels . It is well-known that tumor growth is angiogenesis-dependent. Vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) stimulated vascular endothelial cell proliferation and are involved in the neoplastic angiogenesis of several types of tumors including those of the intestinal tract.Authors usually investigated VEGF and bFGF protein expressions using immunohistochemistry or Western blotting and VEGF and bFGF transcripts using reverse transcriptase polymerase chain reaction (RT-PCR). We recently reported in a previous issue of the World Journal of Gastroenterology that cirrhotic liver tissue levels of these two | Muriel Mathonnet Bernard Descottes Denis Valleix Francois Labrousse Véronique Truffinet Yves Denizot | 2006 | World Journal of Gastroenterology2006，12，23： | 27 |
| 5 | 人造血管的生物力学性能表征显示文摘阐述人造血管在满足医疗作用的前提下应该具有的基本生物力学功能,描述和讨论了人造血管生物力学性能表征,以及各表征指标的评价方法和测试手段。文中还就有关表征手段,提出了进一步完善的措施。 | 王璐 丁辛 Durand Bernard | 2003 | 纺织学报2003，24，1： | 28 |
| 6 | Aerosol scattering coefficients and major chemical compositions of fine particles observed at a rural site in the central Pearl River Delta,South China显示文摘During November-December 2010 aerosol scattering coefficients were monitored using a single-waved (525 nm) Nephelometer at a regional monitoring station in the central Pearl River Delta region and 24-hr fine particle (PM 2.5) samples were also collected during the period using quartz filters for the analysis of major chemical components including organic carbon (OC),elemental carbon (EC),sulfate,nitrate and ammonium.In average,these five components accounted for about 85% of PM 2.5 mass and contributed 42% (OC),19% (SO 4 2 -),12% (NO 3 -),8.4% (NH 4+) and 3.7% (EC),to PM 2.5 mass.A relatively higher mass scattering efficiency of 5.3 m 2/g was obtained for fine particles based on the linear regression between scattering coefficients and PM 2.5 mass concentrations.Chemical extinction budget based on IMPROVE approach revealed that ammonium sulfate,particulate organic matter,ammonium nitrate and EC in average contributed about 32%,28%,20% and 6% to the light extinction coefficients,respectively. | Xinming Wang Xiang Ding Xiaoxin Fu Quanfu He Shaoyi Wang Francois Bernard Xiuying Zhao Dui Wu | 2012 | Journal of Environmental Sciences2012，24，1： | 25 |
| 7 | 植物促生菌及其促生机理显示文摘农业生产中农药和化肥的大量使用 ,在提高作物产量的同时也产生了极大的环境问题。随着现代生物科学技术的进步 ,人们对接种微生物促进作物生长和防治作物病害给予了高度重视。 | 黄晓东 季尚宁 Bernard Glick Bruce Greenberg 卢林纲 | 2002 | 现代化农业2002，，6： | 22 |
| 8 | Rice CYP703A3, a cytochrome P450 hydroxylase, is essential for development of anther cuticle and pollen exine显示文摘Anther cuticle and pollen exine act as protective envelopes for the male gametophyte or pollen grain, but the mechanism underlying the synthesis of these lipidic polymers remains unclear. Previously, a tapetum‐expressed CYP703A3, a putative cytochrome P450 fatty acid hydroxylase, was shown to be essential for male fertility in rice(Oryza sativa L.). However,the biochemical and biological roles of CYP703A3 has not been characterized. Here, we observed that cyp703a3‐2 caused by one base insertion in CYP703A3 displays defective pollen exine and anther epicuticular layer, which differs from Arabidopsis cyp703a2 in which only defective pollen exine occurs. Consistently, chemical composition assay showed that levels of cutin monomers and wax components were dramatically reduced in cyp703a3‐2 anthers. Unlike the wide range of substrates of Arabidopsis CYP703A2, CYP703A3 functions as an in‐chain hydroxylase only for a specific substrate, lauric acid, preferably generating 7‐hydroxylated lauric acid. Moreover, chromatin immunoprecipitation and expression analyses revealed that the expression of CYP703A3 is directly regulated by Tapetum Degeneration Retardation, a known regulator of tapetum PCD and pollen exine formation. Collectively, our results suggest that CYP703A3 represents a conserved and diversified biochemical pathway for in‐chain hydroxylation of lauric acid required for the development of male organ in higher plants. | Xijia Yang Di Wu Jianxin Shi Yi He Franck Pinot Bernard Grausem Changsong Yin Lu Zhu Mingjiao Chen Zhijing Luo Wanqi Liang Dabing Zhang | 2014 | Journal of Integrative Plant Biology2014，56，10： | 21 |
| 9 | Cultured meat from muscle stem cells: A review of challenges and prospects显示文摘Growing muscle tissue in culture from animal stem cells to produce meat theoretically eliminates the need to sacrifice animals. So-called 'cultured' or 'synthetic' or 'in vitro' meat could in theory be constructed with different characteristics and be produced faster and more efficiently than traditional meat. The technique to generate cultured muscle tissues from stem cells was described long ago, but has not yet been developed for the commercial production of cultured meat products. The technology is at an early stage and prerequisites of implementation include a reasonably high level of consumer acceptance, and the development of commercially-viable means of large scale production. Recent advancements in tissue culture techniques suggest that production may be economically feasible, provided it has physical properties in terms of colour, flavour, aroma, texture and palatability that are comparable to conventional meat. Although considerable progress has been made during recent years, important issues remain to be resolved, including the characterization of social and ethical constraints, the fine-tuning of culture conditions, and the development of culture media that are cost-effective and free of animal products. Consumer acceptance and confidence in in vitro produced cultured meat might be a significant impediment that hinders the marketing process. | Isam T Kadim Osman Mahgoub Senan Baqir Bernard Faye Roger Purchas | 2015 | Journal of Integrative Agriculture2015，14，2： | 20 |
| 10 | 在直肠的癌症的磁性的回声成像调查结果的临床的意义显示文摘 Staging of rectal cancer is essential to help guide clini-cians to decide upon the correct type of surgery and determine whether or not neoadjuvant therapy is indicated. Magnetic resonance imaging (MRI) is currently one of the most accurate modalities on which to base treatment decisions for patients with rectal cancer. MRI can accurately detect the mesorectal fascia, assess the invasion of the mesorectum or surrounding organs and predict the circumferential resection margin. Although nodal disease remains a difficult radiological diagnosis, new lymphographic agents and diffusion weighted imaging may allow identification of metastatic nodes by criteria other then size. In light of this, we have reviewed the literature on the accuracy of specific MRI findings for staging the local extent of primary rectal cancer. The aim of this review is to establish a correlation between MRI findings, prognosis, and available treatment options. | Charles F Bellows Bernard Jaffe Lorenzo Bacigalupo Salvatore Pucciarelli Guiseppe Gagliardi | 2011 | World Journal of Radiology2011，3，4： | 19 |
| 11 | 滑铁卢大学植物促生菌技术的研究与开发显示文摘加拿大滑铁卢大学研究与开发的植物促生菌技术主要是利用促进植物生长的根际微生物、降解农药残留和有机物污染的根际微生物与预防和控制流行性病菌对植物侵染物的微生物以及它们与植物的关系 ,实现促进作物生长 ,增强作物对农药抗性 ,降解农药残留 ,减少化肥使用 ,增加投入化肥效益 ,促进土壤中无效营养有效化 ,预防和控制作物的各种流行性病害 ,减少作业成本 ,提高产品产量和质量。该项技术成本低 ,适应性广 ,实施简便、安全。该项技术的关键是根据适当的植物、土壤和气候条件 。 | 黄晓东 季尚宁 Bernard Glick Bruce Greenberg 卢林纲 | 2002 | 现代化农业2002，，10： | 19 |
| 12 | 中国环境镉接触人群低骨密度及肾功能不全的研究显示文摘25年前,Ambio曾载文提出应警惕环境镉污染引起的健康效应。1998年在中国进行了这方面的研究,评价了因食用大米而接触镉人群的前臂骨密度(BMD)和肾功能,发现尿镉(CdU) 或血镉(CdB)高的绝经后妇女及血镉(CdB)高的男性,BMD均有所下降。在CdB或CdU与肾功能不全(视黄醇结合蛋白排泄增加)之间也发现了明显的、有统计学意义的剂量-效应关系及剂量-反应关系。第一次报道了日本以外的亚洲地区镉接触人群中存在骨不良效应。本文的意义在于阐明了亚洲的环境镉接触人群中仍存在着与肾和骨(镉的比较严重的有害效应)的联合效应,也讨论了一些欧洲镉接触人群的骨效应。 | Gunnar Nordberg 金泰廙 Alfred Bernard Sebastien Fierens Jean Pierre Buchet 叶葶葶 孔庆瑚 王洪复 | 2002 | AMBIO-人类环境杂志2002，31，6： | 19 |
| 13 | The influence of land use change on the spatial–temporal variability of habitat quality between 1990 and 2010 in Northeast China显示文摘Land use changes are a direct consequence of interactions between humans and nature.Analysing the spatial and temporal changes in habitat quality brought about by land use change can provide a scientific basis for ecological protection and land planning.Based on the analysis of land use change from 1990 to 2010 in Northeast China,we used the InVEST(integrated valuation of ecosystem services and trade-offs)module to evaluate habitat quality based on watershed subdivision.The results show that:(1)the main land use changes from 1990 to 2010 were the transition from grasslands and forest lands to agricultural lands,which led to a decrease in connectivity of landscape and an increase in fragmentation;(2)areas of high habitat quality were distributed north of the Greater Khingan Mountains,the region of the Lesser Khingan Mountains and east of the Changbai Mountains,while the central plain had low habitat quality;(3)agricultural lands had the largest effect on habitat degradation among all habitat threats.During these 2 decades,the contribution of agricultural lands to habitat degradation were 43.4%in 1990,44.6%in 2000 and 43.9%in 2010;and,(4)at a landscape scale,patch density and splitting index present noticeable negative correlations with habitat quality index.Habitat quality was significantly affected by landscape fragmentation and decreased connectivity. | Limin Dai Shanlin Li Bernard J.Lewis Jian Wu Dapao Yu Wangming Zhou Li Zhou Shengnan Wu | 2019 | Journal of Forestry Research2019，30，6： | 18 |
| 14 | Radiofrequency ablation for treatment of hypersplenism: A feasible therapeutic option显示文摘We present a case of a patient with hypersplenism secondary to portal hypertension due to hepato-splenic schistosomiasis, which was accompanied by severe and refractory thrombocytopenia. We performed spleen ablation and measured the total spleen and ablated volumes with contrast-enhanced computed tomography and volumetry. No major complications occurred, thrombocytopenia was resolved, and platelet levels remained stable, which allowed for early treatment of the patient's underlying disease. Previous work has shown that splenic radiofrequency ablation is an attractive alternative treatment for hypersplenism induced by liver cirrhosis. We aimed to contribute to the currently sparse literature evaluating the role of radiofrequency ablation(RFA) in the management of hypersplenism. We conclude that splenic RFA appears to be a viable and promising option for the treatment of hypersplenism. | Guilherme Lopes P Martins Joao Paulo G Bernardes Marcello S Rovella Raphael G Andrade Publio Cesar C Viana Paulo Herman Giovanni Guido Cerri Marcos Roberto Menezes | 2015 | World Journal of Gastroenterology2015，21，20： | 17 |
| 15 | Endoscopic and histologic characteristics of serrated lesions显示文摘In recent years , a second pathway for colonic carcinogenesis , distinct from the adenomatous pathway, has been explored. This is referred to as serrated pathway and includes three types of polyp,characterised by a serrated appearance of the crypts:hyperplastic polyps(HP),sessile serrated adenomas(SSA)or lesions,and traditional serrated adenomas.Each lesion has its own genetic,as well as macroscopic and microscopic morphological features.Because of their flat aspect,their detection is easier with chromoendoscopy(carmin indigo or narrow-band imaging).However,as we show in this review,the distinction between SSA and HP is quite difficult.It is now recommended to resect in one piece as it is possible the serrated polyps with a control in a delay depending on the presence or not of dysplasia.These different types of lesion are described in detail in the present review in general population,in polyposis and in inflammatory bowel diseases patients.This review highlights the need to improve characterization and understanding of this way of colorectal cancerogenesis. | Driffa Moussata Gilles Boschetti Marion Chauvenet Karine Stroeymeyt Stéphane Nancey Franoise Berger Thierry Lecomte Bernard Flourié | 2015 | World Journal of Gastroenterology2015，21，10： | 14 |
| 16 | 采矿地质因素评定冲击地压危险显示文摘冲击地压危险状态可通过分析岩体内的应力、岩体特性、煤层特征等地质因素和开采技术因素来确定。冲击地压危险性指数是根据已发生的冲击矿压事故来确定的。实践证明 ,这种方法对圈定区域性冲击危险程度 。 | 王蓓 吴继忠 Bernard DRZEZLA | 2001 | 矿山压力与顶板管理2001，18，1： | 14 |
| 17 | Growth and nutrient dynamics of Betula alnoides seedlings under exponential fertilization显示文摘Betula alnoides is a fast-growing hardwood species grown in large plantations in Southeast Asia and South China.Nitrogen requirements for producing robus seedlings,growth and nutrient dynamics were investigated using exponential fertilization treatments.Root collar diameter,height,dry mass and nutrient contents of seedlings increased exponentially in all fertilization treatments as time progressed.Moreover,with water soluble fertilizer(Plant Products plus microelements N–P_2O_5–K_2O:20–20–20),300 mg N seedling^(-1)was adequate.Vector analysis revealed that P was the most responsive nutrient element followed by N and K.Dilutions of N and K were evident in the plants without N addition,which induced initial P sufficiency and then luxury consumption probably due to the antagonistic interaction between N and P.However deficiencies of N,P and K were mostly observed in al exponential regimes during the experiment because seedling growth rate exceeded nutrient uptake rate,inferring that further study on improving the nutrient uptake efficiency is needed.Analysis of relationships among nutrient supply,dry mass,N content and N concentration demonstrated that 100–400 mg N seedling^(-1)induced sufficiency to luxury consumption of nitrogen without significant change in dry mass,and 400 mg N seedling^(-1)is recommended to apply for nutrient loading of seedlings before outplanting.The findings will help improve seedling quality and enhance the production of robust seedlings for plantation forestry of this species. | Lin Chen Chunsheng Wang Bernard Dell Zhigang Zhao Junjie Guo Daping Xu Jie Zeng | 2018 | Journal of Forestry Research2018，29，1： | 14 |
| 18 | 近年来热等静压(HIP)处理与应用发展趋势显示文摘自1970年以来,高温合金、不锈钢及钛等主要的大型粉末冶金(PM)近终形零件,已广泛采用热等静压(HIP)处理,从1970年以来,已安装的约有1 000台热等静压装置(这些HIP装置约50%是用于研究与开发的)。HIP装置也用于使铸件致密化处理、扩散粘结与包层及使硬质合金致密化。这篇述评主要着眼于HIP技术和粉末材料应用的发展趋势。 | Bernard Williams 韩凤麟 | 2014 | 粉末冶金技术2014，32，6： | 13 |
| 19 | 技术视野 人文情怀——国内首届“交互与信息行为研究学术研讨会”纪要显示文摘1 引言信息行为研究一直都是图书情报领域的核心研究内容。在网络信息资源不断丰富和发展的今天,'交互'已然成为用户获取各类信息资源最普遍的行为。为推动国内外信息行为、交互式信息检索及相关领域的学术研究、交流与合作,探索相关问题的研究思路、方法和路径,促进情报学相关学科领域的不断发展,南开大学商学院信息资源管理系与南开大学信息行为科学研究中心于2019年5月13—14日举办了 '交互与信息行为研究学术研讨会'。 | Bernard Jim Jansen 吴丹 李凯 黄崑 姜婷婷 张鹏翼 赵宇翔 张晓飞 刘畅 李月琳 权明喆(整理) 丁念(整理) | 2019 | 图书情报知识2019，0，4： | 13 |
| 20 | Predictive factors of survival in patients treated with definitive chemoradiotherapy for squamous cell esophageal carcinoma显示文摘瞄准:学习的目的是与食道的癌(LASCOC ) 与权威的 chemoradiotherapy (CRT ) 对待的局部地先进的有鳞的房间在病人评估幸存的预兆的因素政体基于 5FU/CDDP 联合。方法:有用在 1994 和 2000 之间的 5FU/CDDP 联合与权威的 CRT 对待的 LASCOC 的所有病人回顾地被包括。对 CRT 的临床的完全的反应(CCR ) 被食道的内视镜检查法和 CT 扫描估计在 CRT 结束以后的 2 瞬间。幸存的预示的因素用 univariate 被估计,多,由艇长回归的变量分析当模特儿。结果:116 个病人的一个总数在学习被包括。到 CRT 的 CCR 在 86/116 (74.1%) 被观察。中部的幸存是 20 瞬间(范围 2-114 ) , 5 年的幸存是 9.4% 。到 CRT 的应答者病人的中部的幸存在非应答者病人作为与 9 瞬间(范围 2-81 ) 相比是 25 瞬间(范围 3-114 )(P <
0.001 ) 。在 univariate 分析,幸存与 CCR 被联系(P <
0.001 ) ,表演地位 <
2 (P = 0.01 ) ,瘤长度 <
6 厘米(P = 0.045 ) 并且 10% 在意义的限制的重量损失 <
(P = 0.053 ) 。在里面多变量分析,幸存对 CCR 依赖(P <
0.0001 ) ,重量损失 <
10%(P = 0.034 ) 并且表演 <
2 (P = 0.046 ) 。结论:我们的结果建议在有与权威的 CRT 对待的 LASCOC 的病人的那幸存被相关到 CCR,重量损失并且表演地位。 | Frédéric Di Fiore Stéphane Lecleire Olivier Rigal Marie-Pierre Galais Emmanuel Ben Soussan Isabelle David Bernard Paillot Jacques-Henri Jacob Pierre Michel | 2006 | World Journal of Gastroenterology2006，12，26： | 13 |
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