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| 1 | Protective effects of intravenous anesthetics on kidney tissue in obstructive jaundice显示文摘AIM:To evaluate the protective effects on kidney tissue of frequently used intravenous anesthetics(ketamine,propofol,thiopental,and fentanyl)in rats with obstructive jaundice.METHODS:There is an increased incidence of postoperative acute renal failure in patients with obstructive jaundice.Thirty-two Wistar-albino rats were randomly divided into four equal groups.Laparatomy was performed on each animal in the four groups and common bile ducts were ligated and severed on day 0.After 7 d,laparotomy was again performed using ketamine,propofol,thiopental,or fentanyl anesthesia whose antioxidative properties are well known in oxidative stress in a rat liver model of obstructive jaundice.After 2 h,the rats were sacrificed.Renal tissue specimens were analyzed for catalase,superoxide dismutase and malondialdehyde enzymes activities.All values are expressed as the mean±SD.P values less than 0.05 were considered statistically significant.RESULTS:All animals survived without complications until the end of the study.Enlargement in the bile duct and obstructive jaundice were observed in all rats.Catalase was found to be significantly lower in the fentanyl group than in the ketamine(P=0.039),propofol(P=0.012),and thiopental(P=0.001)groups.Superoxide dismutase activities were similar in all groups(P>0.05).Malondialdehyde was found to be significantly lower in the ketamine group than in the propofol(P=0.028),thiopental(P=0.002)and fentanyl(P=0.005)groups.Malondialdehyde was also lower in the fentanyl group than in the thiopental group(P=0.001).The results showed that obstructive jaundice sensitizes renal tissue to damage under the different anesthetics.CONCLUSION:Among the agents tested,ketamine and propofol generated the least amount of oxidative stres on renal tissues in this rat model of obstructive jaundice created by common bile duct ligation.The importance of free radical injury in renal tissue in obstructive jaundice under different intravenous anesthetics during hepatobiliary and liver transplant surgery should be considered for prevention of postoperative acute renal failure. | Sinan Hatipoglu Huseyin Yildiz Ertan Bulbuloglu Ismail Coskuner Ergul Belge Kurutas Filiz Hatipoglu Harun Ciralik Mehmet Sait Berhuni | 2014 | World Journal of Gastroenterology2014，20，12： | 9 |
| 2 | Vitamin B complex and vitamin B12 levels after peripheral nerve injury显示文摘The aim of the present study was to evaluate whether tissue levels of vitamin B complex and vitamin B12 were altered after crush-induced peripheral nerve injury in an experimental rat model. A total of 80 male Wistar rats were randomized into one control(n = 8) and six study groups(1, 6, 12, 24 hours, 3, and 7 days after experimental nerve injury; n = 12 for each group). Crush-induced peripheral nerve injury was performed on the sciatic nerves of rats in six study groups. Tissue samples from the sites of peripheral nerve injury were obtained at 1, 6, 12, 24 hours, 3 and 7 days after experimental nerve injury. Enzyme-linked immunosorbent assay results showed that tissue levels of vitamin B complex and vitamin B12 in the injured sciatic nerve were significantly greater at 1 and 12 hours after experimental nerve injury, while they were significantly lower at 7 days than in control group. Tissue level of vitamin B_(12) in the injured sciatic nerve was significantly lower at 1, 6, 12 and 24 hours than in the control group. These results suggest that tissue levels of vitamin B complex and vitamin B_(12) vary with progression of crush-induced peripheral nerve injury, and supplementation of these vitamins in the acute period may be beneficial for acceleration of nerve regeneration. | Idiris Altun Ergül Belge Kurutas | 2016 | Neural Regeneration Research2016，11，5： | 6 |
| 3 | 比较应用对比增强MR与多层CT检测急性和慢性心肌梗死的特点 | Gerber B.L. Belge B. Legros G.J. 吴晓燕 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，0，7： | 4 |
| 4 | Tourism and urban public transport: Holding demand pressure under supply con- straints 显示文摘 | ALBALATE D BELG | 2010 | Tourism Management2010，31，3： | 1 |
| 5 | A technique of duodenal cannulation in sheep显示文摘 | Belge A Bakr B zcelik A | 1980 | J Anita Sci1980，51，1： | 1 |
| 6 | Regulation of the mammalian heart function by nitric oxide显示文摘 | MASSION P B PELAT M BELGE C | 2005 | Comp Biochem Physiol A Mol Integr Physiol2005，142，2： | 1 |
| 7 | Accurate estimation of global and regional cardiac function by retrospectively gated multidetector row computed tomography:comparison with cine magnetic resonance imaging显示文摘 | Belge B Coche E Pasquet A | 2006 | Eur Radiol2006，16，7： | 1 |
| 8 | Preparation andapplication of new monosized polymer particles显示文摘 | Ugelstad J Belge A Ellingsent T | 1992 | ProgPolym Sci1992，17，： | 1 |
| 9 | Oxidative stress in patients with scalp seborrheic dermatitis显示文摘 | OZTURK P ARICAN O BELGE K E | 2013 | Acta Dermatovenerol Croat2013，21，2： | 1 |
| 10 | Enhanced expression of beta3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase显示文摘 | Belge C Hammond J Dubois-Deruy E | 2014 | Circulation2014，129，4： | 1 |
| 11 | Preparation and application of new monosized poly mer partieles显示文摘 | UGELSTAD J BELGE A ELLINGSEN T | 1992 | Prog Polym Sci1992，17，： | 1 |
| 12 | Characterization of acute and chronic myocardial infarcts by multidetector computed tomography:comparison with contrast-enhanced magnetic resonance显示文摘 | Gerber BL Belge B Legros GJ | 2006 | Circulation2006，113，6： | 1 |
| 13 | Characterization of acute and chronic myocardial infarcts by multidetector computed tomography:comparison with contrast-enhanced magnetic resonance显示文摘 | Gerber BL Belge B Legros G J | | Circulation0，，： | 1 |
| 14 | Indirect Electrochemical T~atment of hisphenol A in water via electrochemically generated Fenton's reagent 显示文摘 | Belg~n G Mehmet A O Nihal O | 2003 | Environmental Science and Teehnohw2003，37，： | 1 |
| 15 | High Mallampati score and nasal obstruction are associated risk factors for obstructive sleep apnea显示文摘 | Liistro G Rombaux P Belge C | | 0，，02： | 1 |
| 16 | Non-invasive ventilation in amyotrophic lateral sclerosis显示文摘 | Vrijsen B Testelmans D Belge C | 2013 | Amyotroph Lateral Scler Frontotemporal Degener2013，14，2： | 1 |
| 17 | Wavelet domain image restoration with adaptive edge-preserving regularization显示文摘 | Belge M Kilmer M E Miller E L | 2000 | IEEE Transactions on Image Processing2000，9，4： | 1 |
| 18 | Wavelet domain image restoration with adaptive edge-preserving regularization显示文摘 | Belge Murat Kilmer Misha E Miller Eric L | 2000 | IEEE Transaction on Image Processing2000，9，4： | 1 |
| 19 | mammalian heart function by nitric oxide 显示文摘 | Massion P B Pelat Regulation of the M Belge C | 2005 | Comp Biochiem Physiol A MO1 Integr Physiol2005，142，2： | 1 |
| 20 | Up-regulation of the high mobility group AT-hook 2 gene in acute aortic dissection is potentially associated with endo- thelial-mesenchymal transition 显示文摘 | Belge G Radtke A Meyer A | 2011 | Histol Histopathol2011，26，8： | 1 |
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