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| 1 | Iliac vein compression syndrome: Clinical, imaging and pathologic findings显示文摘May-Thurner syndrome(MTS) is the pathologic compression of the left common iliac vein by the right common iliac artery, resulting in left lower extremity pain, swelling, and deep venous thrombosis. Though this syndrome was first described in 1851, there are currently no standardized criteria to establish the diagnosis of MTS. Since MTS is treated by a wide array of specialties, including interventional radiology, vascular surgery, cardiology, and vascular medicine, the need for an established diagnostic criterion is imperative in order to reduce misdiagnosis and inappropriate treatment. Although MTS has historically been diagnosed by the presence of pathologic features, the use of dynamic imaging techniques has led to a more radiologic based diagnosis. Thus, imaging plays an integral part in screening patients for MTS, and the utility of a wide array of imaging modalities has been evaluated. Here, we summarize the historical aspects of the clinical features of this syndrome. We then provide a comprehensive assessment of the literature on the efficacy of imaging tools available to diagnose MTS. Lastly, we provide clinical pearls and recommendations to aid physicians in diagnosing the syndrome through the use of provocative measures. | Katelyn N Brinegar Rahul A Sheth Ali Khademhosseini Jemianne Bautista Rahmi Oklu | 2015 | World Journal of Radiology2015，7，11： | 36 |
| 2 | Review of natural products with hepatoprotective effects显示文摘The liver is one of the most important organs in the body,performing a fundamental role in the regulationof diverse processes,among which the metabolism,secretion,storage,and detoxification of endogenous and exogenous substances are prominent.Due to these functions,hepatic diseases continue to be among the main threats to public health,and they remain problems throughout the world.Despite enormous advances in modern medicine,there are no completely effective drugs that stimulate hepatic function,that offer complete protection of the organ,or that help to regenerate hepatic cells.Thus,it is necessary to identify pharmaceutical alternatives for the treatment of liver diseases,with the aim of these alternatives being more effective and less toxic.The use of some plants and the consumption of different fruits have played basic roles in human health care,and diverse scientific investigations have indicated that,in those plants and fruits so identified,their beneficial effects can be attributed to the presence of chemical compounds that are called phytochemicals.The present review had as its objective the collecting of data based on research conducted into some fruits(grapefruit,cranberries,and grapes)and plants[cactus pear(nopal)and cactus pear fruit,chamomile,silymarin,and spirulina],which are consumed frequently by humans and which have demonstrated hepatoprotective capacity,as well as an analysis of a resin(propolis)and some phytochemicals extracted from fruits,plants,yeasts,and algae,which have been evaluated in different models of hepatotoxicity. | Eduardo Madrigal-Santillán Eduardo Madrigal-Bujaidar Isela álvarez-González María Teresa Sumaya-Martínez José Gutiérrez-Salinas Mirandeli Bautista ángel Morales-González Manuel García-Luna y González-Rubio J Leopoldo Aguilar-Faisal José A Morales-González | 2014 | World Journal of Gastroenterology2014，20，40： | 10 |
| 3 | Alzheimer’s disease and type 2 diabetes mellitus:Pathophysiologic and pharmacotherapeutics links显示文摘At present,Alzheimer’s disease(AD)and type 2 diabetes mellitus(T2DM)are two highly prevalent disorders worldwide,especially among elderly individuals.T2DM appears to be associated with cognitive dysfunction,with a higher risk of developing neurocognitive disorders,including AD.These diseases have been observed to share various pathophysiological mechanisms,including alterations in insulin signaling,defects in glucose transporters(GLUTs),and mitochondrial dysfunctions in the brain.Therefore,the aim of this review is to summarize the current knowledge regarding the molecular mechanisms implicated in the association of these pathologies as well as recent therapeutic alternatives.In this context,the hyperphosphorylation of tau and the formation of neurofibrillary tangles have been associated with the dysfunction of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in the nervous tissues as well as the decrease in the expression of GLUT-1 and GLUT-3 in the different areas of the brain,increase in reactive oxygen species,and production of mitochondrial alterations that occur in T2DM.These findings have contributed to the implementation of overlapping pharmacological interventions based on the use of insulin and antidiabetic drugs,or,more recently,azeliragon,amylin,among others,which have shown possible beneficial effects in diabetic patients diagnosed with AD. | Milagros Rojas Mervin Chávez-Castillo Jordan Bautista Ángel Ortega Manuel Nava Juan Salazar Edgar Díaz-Camargo Oscar Medina Joselyn Rojas-Quintero Valmore Bermúdez | 2021 | World Journal of Diabetes2021，12，6： | 5 |
| 4 | s Early-onset in Major Depression a Predictor of Specific Clinical Features with More Impaired Social Function?显示文摘Background: Early-onset major depressive disorder (MDD) (EOD) is often particularly malignant due to its special clinical features, accompanying impaired social function, protracted recovery time, and frequent recurrence. This study aimed to observe the effects of age onset on clinical characteristics and social function in MDD patients in Asia. Methods: In total, 547 out-patients aged 18-5 years who were from 13 study sites in five Asian countries were included. These patients had MDD diagnose according to the Diagnostic and Statistical Manual of Mental Disorders, 4^th Edition criteria. Clinical features and social function were assessed using Symptom Checklist-90-revised (SCL-90-R) and Sheehan Disability Scale (SDS). Quality of life was assessed by a 36-item Short-form Health Survey (SF-36). Analyses were performed using a continuous or dichotomous (cut-off: 30 years) age-of-onset indicator. Results: Early-onset MDD (EOD, 〈30 years) was associated with longer illness (P - 0.003), unmarried status (P 〈 0.001), higher neuroticism (P 〈 0.002) based on the SCL-90-R, and more limited social function and mental health (P = 0.006, P = 0.007) based on the SF-36 and SDS. The impairment of social function and clinical severity were more prominent at in-patients with younger onset ages. Special clinical features and more impaired social function and quality of life were associated with EOD, as in western studies. Conclusions: EOD often follows higher levels of neuroticism. Age of onset of MDD may be a predictor of clinical features and impaired social function, allowing earlier diagnosis and treatment. | Yan-Hong Liu Lin Chen Yun-Ai Su Yi-Ru Fang Manit Srisurapanont Jin Pyo Hong Ahmad Hatim Hong Choon Chua Dianne Bautista Tian-Mei Si | 2015 | Chinese Medical Journal2015，，6： | 5 |
| 5 | Does an association exist between chronic pancreatitis and liver cirrhosis in alcoholic subjects?显示文摘AIM: To study the possible association between chronic pancreatitis (CP) and liver cirrhosis (LC) of alcoholic etiology,after excluding any other causes.METHODS: One hundred and forty consecutive alcoholic patients were subdivided into three groups: CP (n = 53),LC (n = 57),and asymptomatic alcoholic (n = 30).Clinical,biochemical and morphological characteristics,Child-Pugh index,indocyanine green test,and fecal pancreatic elastase-1 test were assessed.RESULTS: In patients with cirrhosis,major clinical manifestations of CP such as pancreatic pain and steatorrhea,as well as imaging alterations of CP such as calcifications,duct dilation and pseudocysts were absent; insulin-dependent diabetes was present in 5.3% of cases,and elastase-1 test was altered in only 7%,and severely altered in none.In patients with CP,clinical characteristics of cirrhosis such as ascites,encephalopathy and gastrointestinal hemorrhage were present in one case,Child-Pugh grade > A in 5.7%,and altered indocyanine green test in 1.9% cases.In asymptomatic alcoholism,there was only a non-coincident alteration of elastase-1 test and indocyanine test in 14.8% and 10%,respectively,but other characteristics of cirrhosis or CP were absent.An inverse correlation (r = -0.746) between elastase-1 test and indocyanine test was found in alcoholic patients.CONCLUSION: There is a scarce coincidence in clinical and morphological alterations among patients with CP or LC of alcoholic etiology,but an inverse correlation between pancreatic and liver function tests.These findings support that these alcoholic diseases evolve in a different manner and have different etiopathogenesis. | Luis Aparisi Luis Sabater Juan Del-Olmo Juan Sastre Miguel-Angel Serra Ricardo Campello Daniel Bautista Abdalla Wassel José-Manuel Rodrigo | 2008 | World Journal of Gastroenterology2008，14，40： | 4 |
| 6 | The exchange rate–interest differential relationship in six East Asian countries显示文摘 | Carlos C. Bautista | 2006 | Economics Letters2006，，1： | 2 |
| 7 | Leuprolide acetate induces structural and functional recovery of injured spinal cord in rats显示文摘Gonadotropin-releasing hormone(Gn RH) and its synthetic analog leuprolide acetate, a Gn RH agonist, have neurotrophic properties. This study was designed to determine whether administration of leuprolide acetate can improve locomotor behavior, gait, micturition reflex, spinal cord morphology and the amount of microglia in the lesion epicenter after spinal cord injury in rats. Rats with spinal cord compression injury were administered leuprolide acetate or saline solution for 5 weeks. At the 5th week, leuprolide acetate-treated rats showed locomotor activity recovery by 38%, had improvement in kinematic gait and exhibited voiding reflex recovery by 60%, as compared with the 1st week. By contrast, saline solution-treated rats showed locomotor activity recovery only by 7%, but voiding reflex did not recover. More importantly, leuprolide acetate treatment reduced microglial immunological reaction and induced a trend towards greater area of white and gray matter in the spinal cord. Therefore, leuprolide acetate has great potential to repair spinal cord injury. | Carmen Díaz Galindo Beatriz Gómez-González Eva Salinas Denisse Calderón-Vallejo Irma Hernández-Jasso Eduardo Bautista J Luis Quintanar | 2015 | Neural Regeneration Research2015，10，11： | 2 |
| 8 | Association between red blood cell distribution width and the risk of future cardiovascular events显示文摘 | Amparo Vaya José Luis Hernández Esther Zorio Daniel Bautista | 2011 | Clinical Hemorheology and Microcirculation2011，，3： | 2 |
| 9 | Silica antireflective films on glass produced by the sol–gel method显示文摘 | M.C. Bautista A. Morales | 2003 | Solar Energy Materials and Solar Cells2003，，2： | 2 |
| 10 | The grafting of triploid watermelon is an advantageous alternative to soil fumigation by methyl bromide for control of Fusarium wilt显示文摘 | A. Miguel J.V. Maroto A. San Bautista C. Baixauli V. Cebolla B. Pascual S. López J.L. Guardiola | 2004 | Scientia Horticulturae2004，，1： | 2 |
| 11 | 2014年猪场五种病毒性疾病的血清抗体检测显示文摘采用ELISA方法,对186个中小规模猪场的母猪群、保育猪群和育肥猪群的1400余份血清检测猪瘟、伪狂犬病、猪繁殖与呼吸障碍综合征、圆环病毒2型和口蹄疫O型的抗体水平。结果表明,75%~87%的猪群抗体水平合格,种猪群抗体合格率高于保育猪群和育肥猪群。伪狂犬病野毒gE抗体阳性率较高,母猪群中gE抗体阳性样品数占检测样品总数的40.93%,而母猪群中阳性场占总场数的89.74%。 | Gloria Solano Elida Bautista Thomas Molitor Joaquim Segalés Carlos Pijoan 丁文格 朱秀高 叶晶 侯博 蒋文明 石勇耀 程福生 樊学坤 陆军 熊剑锋 唐万勇 | 2015 | 中国猪业2015，10，8： | 2 |
| 12 | TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents 显示文摘 | Bautista DM Jordt SE Nikai T | 2006 | Cell2006，124，： | 1 |
| 13 | On Higher Order Statistics of the Nakagami-m Distribution显示文摘 | VARGAS BAUTISTA J E | 1999 | IEEE Transaction on Vehicular Technology1999，48，3： | 1 |
| 14 | The long-term effect of doxazosin,Finasteride,and combination therapy on the clinieal progression of benign prostatic hyperplasia显示文摘 | McConnell JD Roehrbom CG Bautista OM | 2003 | N Engl J Med2003，349，： | 1 |
| 15 | Immunity to PRRSV:Double-edged sword显示文摘 | Molitor T W Bautista E M Choi C S | 1997 | Vet Microbiol1997，55，： | 1 |
| 16 | Immunity to PRRSV:Double-edged sword显示文摘 | Molitor T W Bautista E M Choi C S | 1997 | Veterinary Microbiology1997，55，： | 1 |
| 17 | Interleavers make high channelcount systems economical显示文摘 | SHINE B BAUTISTA J | 2000 | Lightwave2000，，8： | 1 |
| 18 | Characterization of porous aluminium oxide films from AC impedance measurements 显示文摘 | Gonzalez J A Lopez V Bautista A | 1999 | Journal of Applied Electrochemical1999，29，2： | 1 |
| 19 | Calcium-sensitive potassi- um channelopathy in human epilepsy and paroxysmal move- ment disorder显示文摘 | Du W Bautista J F Yang H | 2005 | Nat Genet2005，37，7： | 1 |
| 20 | Production of soluble enzymatic protein hydrolysate from industrially defatted undehulled sunflower meal 显示文摘 | Parrado J Bautista J Machado A | 1991 | Journal of Agriculture and Food Chemistry1991，39，4： | 1 |
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