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| 1 | Adult Burkitt like lympho- ma of the colon:a case report and a review of the literature显示文摘 | Bassem M Chehab Thomas K | 2008 | Gas''c roint esinal endoscopy2008，67，： | 1 |
| 2 | A new software quality model for evaluating COTS components 显示文摘 | ADNAN R BASSEM M | 2006 | Journal of Computer Scinece2006，2，4： | 1 |
| 3 | The dewvaporation tower: an experimental & theoretical study with economic analysis 显示文摘 | Bassem M Hamieh James R Beckman and Michael D Ybarra | 2000 | Desalination & Water Reuse2000，10，2： | 1 |
| 4 | Numerical study of coupled heat and mass transfer in geothermal water cooling tower 显示文摘 | Bourouni K Bassem M M Chaibi M T | 2008 | Energy Conversion and Management2008，49，： | 1 |
| 5 | A fuzzy logic model for medical equipment risk classification显示文摘 | Tawfik B Bassem K Yassin M | 2013 | Clin Eng2013，38，4： | 1 |
| 6 | Numerical study of coupled heat and mass transfer in geothermal water cooling tower显示文摘 | Bourouni K Bassem M M Chaibi M T | 2008 | Energy Conversion and Management2008，49，6： | 1 |
| 7 | Application ofshape memory alloy dampers in the seismic control of cable-staeyed bridge显示文摘 | Alaa M Sharabash Bassem O Andrawes | 2009 | Eng Strutures2009，31，2： | 1 |
| 8 | Response surface optimi- zation for determination of volatile organic compounds in water samples by headspace-Gas Chromatography-Mass spectrometry method 显示文摘 | Ines M Lotfi S Bassem J | 2009 | J Chromatogr Sci2009，47，4： | 1 |
| 9 | Radar Systems Analysis and Design Using Matlab显示文摘 | Bassem R M Huntsville Alabama | 2000 | CRC Press2000，，： | 1 |
| 10 | Application of shape memory alloy dampers in the seismic control of cable-stayed bridges 显示文摘 | Alaa M Sharabash Bassem 0 Andrawes | 2009 | Engineering Structures2009，31，2： | 1 |
| 11 | Hepatic and gastrointestinal disturbances in Egyptian patients infected with coronavirus disease 2019: A multicentre cohort study显示文摘BACKGROUND Various liver and gastrointestinal involvements occur in patients with coronavirus disease 2019(COVID-19)at variable prevalence.Most studies report mild liver function disturbances correlated with COVID-19 severity,though liver failure is unusual.AIM To study liver and gastrointestinal dysfunctions in Egyptian patients with COVID-19 and their relation to disease outcomes METHODS This multicentre cohort study was conducted on 547 Egyptian patients from April 15,2020 to July 29,2020.Consecutive polymerase chain reaction-confirmed COVID-19 cases were included from four quarantine hospitals affiliated to the Egyptian ministry of health.Demographic information,laboratory characteristics,treatments,fibrosis-4(FIB-4)index,COVID-19 severity,and outcomes were recorded and compared according to the degree of liver enzyme elevation and the presence of gastrointestinal symptoms.Follow-ups were conducted until discharge or death.Regression analyses were performed to determine the independent factors affecting mortality.RESULTS This study included 547 patients,of whom 53(9.68%)died during hospitalization and 1 was discharged upon his request.Patients’mean age was 45.04±17.61 years,and 21.98%had severe or critical COVID-19.Alanine aminotransferase(ALT)and aspartate aminotransferase(AST)were available for 430 and 428 patients,respectively.In total,26%and 32%of patients had elevated ALT and AST,respectively.Significant liver injury with ALT or AST elevation exceeding 3-fold was recorded in 21(4.91%)and 16(3.73%)patients,respectively.Male gender,smoking,hypertension,chronic hepatitis C,and lung involvement were associated with elevated AST or ALT.AST was elevated in 50%of patients over 60-years-old.FIB-4 was significantly higher in patients admitted to the intensive care unit(ICU),those with more severe COVID-19,and non-survivors.The independent variables affecting outcome were supplementary vitamin C intake(1 g daily capsules)[odds ratio(OR):0.05,95%confidence interval(CI):0.008–0.337];lung consolidation(OR:4.540,95%CI:1.155–17.840);ICU admission(OR:25.032,95%CI:7.110–88.128);and FIB-4 score>3.25(OR:10.393,95%CI:2.459-43.925).Among 60(13.98%)patients with gastrointestinal symptoms,52(86.67%)had diarrhoea.Patients with gastrointestinal symptoms were predominantly females with higher body mass index,and 50(83.40%)patients had non-severe COVID-19.CONCLUSION Few Egyptian patients with COVID-19 developed a significant liver injury.The independent variables affecting mortality were supplementary vitamin C intake,lung consolidation,ICU admission,and FIB-4 score. | Hend Ibrahim Shousha Shimaa Afify Rabab Maher Noha Asem Eman Fouad Ehab F Mostafa Mohammed A Medhat Amr Abdalazeem Hazem Elmorsy Miriam M Aziz Rateba S Mohammed Mohamed Ibrahem Hassan Elgarem Dalia Omran Mohamed Hassany Bassem Elsayed Ahmed Y Abdelaziz Mohamed El Kassas | 2021 | World Journal of Gastroenterology2021，27，40： | 1 |
| 12 | Impact of high dose vitamin C on platelet function显示文摘AIM To examine the effect of high doses of vitamin C(VitC) on ex vivo human platelets(PLTs).METHODS Platelet concentrates collected for therapeutic or prophylactic transfusions were exposed to:(1) normal saline(control);(2) 0.3 mmol/L VitC(Lo VitC); or(3) 3 mmol/L VitC(Hi VitC, final concentrations) and stored appropriately. The Vit C additive was preservative-free buffered ascorbic acid in water, pH 5.5 to 7.0, adjusted with sodium bicarbonate and sodium hydroxide. The doses of Vit C used here correspond to plasma Vit C levels reported in recently completed clinical trials. Prior to supplementation, a baseline sample was collected for analysis. PLTs were sampled again on days 2, 5 and 8 and assayed for changes in PLT function by: Thromboelastography(TEG), for changes in viscoelastic properties; aggregometry, for PLT aggregation and adenosine triphosphate(ATP) secretion in response to collagen or adenosine diphosphate(ADP); and flow cytometry, for changes in expression of CD-31, CD41 a, CD62 p and CD63. In addition, PLT intracellular Vit C content was measured using a fluorimetric assay for ascorbic acid and PLT poor plasma was used for plasma coagulation tests [prothrombin time(PT), partial thrombplastin time(PTT), functional fibrinogen] and Lipidomics analysis(UPLC ESI-MS/MS).RESULTS VitC supplementation significantly increased PLTs intracellular ascorbic acid levels from 1.2 mmol/L at baseline to 3.2 mmol/L(Lo VitC) and 15.7 mmol/L(Hi VitC, P < 0.05). VitC supplementation did not significantly change PT and PTT values, or functional fibrinogen levels over the 8 d exposure period(P > 0.05). PLT function assayed by TEG, aggregometry and flow cytometry was not significantly altered by Lo or Hi VitC for up to 5 d. However, PLTs exposed to 3 mmol/L VitC for 8 d demonstrated significantly increased R and K times by TEG and a decrease in the α-angle(P < 0.05). There was also a fall of 20 mm in maximum amplitude associated with the Hi VitC compared to both baseline and day 8 saline controls. Platelet aggregation studies, showed uniform declines in collagen and ADP-induced platelet aggregations over the 8-d study period in all three groups(P > 0.05). Collagen and ADP-induced ATP secretion was also not different between the three groups(P > 0.05). Finally, VitC at the higher dose(3 mmol/L) also induced the release of several eicosanoids including thromboxane B2 and prostaglandin E2, as well as products of arachidonic acid metabolism via the lipoxygenases pathway such as 11-/12-/15-hydroxyicosatetraenoic acid(P < 0.05).CONCLUSION Alterations in PLT function by exposure to 3 mmol/L VitC for 8 d suggest that caution should be exerted with prolonged use of intravenous high dose VitC. | Bassem M Mohammed Kimberly W Sanford Bernard J Fisher Erika J Martin Daniel Contaifer Jr Urszula Osinska Warncke Dayanjan S Wijesinghe Charles E Chalfant Donald F Brophy Alpha A Fowler Ⅲ Ramesh Natarajan | 2017 | World Journal of Critical Care Medicine2017，6，1： | 0 |
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