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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Fundamentals of rock joint deformation显示文摘 | Bandis S C Lumsden A C Barton N R | 1983 | International Journal of Rock Mechanics and Mining Sciences & GeomechanicsAbstracts1983，20，6： | 2 |
| 3 | Risk-based inspection planning applied to 14 steel jacket structures显示文摘 | Barton A D Descamps B | 2001 | International Journal of Offshore and Polar Engineering2001，11，1： | 2 |
| 4 | Fundamentals of rock joint deformation显示文摘 | BANDIS S C LUMSDEN A C BARTON N R | 1983 | International Journal of Rock Mechanics and Mining Science and Geomechartics Abstracts1983，20，6： | 1 |
| 5 | Analysis of variation in isolates of Rhizoctonia solani by random amplified polymorohic DNA assay显示文摘 | Duncan S Barton J E O'brien P A | 1993 | Mycol Res1993，15，： | 1 |
| 6 | 显示文摘 | Bahri P A Bandani J A Barton G W | 1995 | Computers and Chemical Engineering1995，，： | 1 |
| 7 | Analysis of variation in isolates of Rhizoctonia solani by random amplified polymorphic DNA assay显示文摘 | Duncan S Barton J E O′Brien P A | 1993 | Mycol Res1993，97，9： | 1 |
| 8 | Comparative wear under four different tribological conditions of acetylene enhanced cross-linked ultra high molecularweight polyethylene显示文摘 | Marrs H Barton D C Jones R A | 1999 | J Mater Sci:Mater Med1999，10，： | 1 |
| 9 | Receptor-mediated gene delivery to human peripheral blood mononuclear cells using anti-CD3 antibody coupled to polyethylenimine显示文摘 | O'NEIL M M KENNEDY C A BARTON R W | 2001 | Gene Therapy2001，，8： | 1 |
| 10 | Effects of Soil Conservation Measures on Erosion Rates and Crop Productivity on Subtropical Ultisols in Yunnan Province,China显示文摘 | BARTON A P FULLEN M A MITCHELL D J | 2004 | Agriculture Ecosystems and Environment2004，104，2： | 1 |
| 11 | Pattern and consequences of interspecific competition in natural communities:a review of field experiments with plants显示文摘 | Goldberg D E Barton A M | 1992 | American Naturalist1992，139，： | 1 |
| 12 | A critical review of complemen- tary therapies for cancer - related fatigue 显示文摘 | Sood A Barton DL Bauer BA | 2007 | Integr Cancer The2007，6，1： | 1 |
| 13 | Crural repair permits morbidly obese patients with not large hiatal hernia to choose laparoscopic adjustable banding as a bariatric surgical treatment显示文摘 | Frezza E E Barton A Wachtel M S | 2008 | Obes Surg2008，18，5： | 1 |
| 14 | Expectant management of severe preeclampsia at 27 (0/7) to 33 ( 6/7 ) weeks gestation : maternal and perinatal outcomes according to gestational age by weeks at onset of expectant management 显示文摘 | BOMBRYS A E BARTON J R HABLI M | 2009 | American Journal of Perinatology2009，26，6： | 1 |
| 15 | Evidence that monoclonal antibodies directed against the integrin β subunit plexin/ semaphorin/integrin domain stimulate function by inducing receptor extension显示文摘 | Mould A P Travis M A Barton S J | 2005 | J Biol Chem2005，280，6： | 1 |
| 16 | Enzyme therapy in type I Gaucher disease : comparative efficacy of mannose-terminated , glucocerebrosidase from natural and recombinant sources 显示文摘 | GRABOWSKI G A BARTON N W PASTORES G | 1995 | Ann Intern Med1995，122，1： | 1 |
| 17 | Expectant management of severe preeclampsia at 27(0/7) to 33(6/7) weeks' gestation:maternal and perinatal outcomes according to gestational age by weeks at onset of expectant management显示文摘 | Bombrys A E Barton J R Habli M | 2009 | Am J Perinatol2009，26，6： | 1 |
| 18 | Distinct Amygdala-autonomic Arousal Profiles in Response to Fear Signals in Healthy Males and Females显示文摘 | WILLIAMS L M BARTON M J KEMP A H | 2005 | Neuroimage2005，，28： | 1 |
| 19 | Comparison of ex- perimental and modelling studies for the microwave drying of ironbark timber显示文摘 | Lehne M Barton G W Langrish T A G | 1999 | Drying Technology1999，17，10： | 1 |
| 20 | MicroRNA control of PHABULOSA in leaf development:importance of pairing to the mieroRNA 5' region 显示文摘 | Mallory A C Reinhart B J Jones-Rhoades M W Tang G L Zamore P D Barton M K Barrel D P | 2004 | The EMBO Journal2004，23，： | 1 |
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