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800篇 您的检索式:作者名="BARTLETT M"
    题名 作者 年代 出处 被引量
1Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease显示文摘The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.Courtney S Schaffert Michael J Duryee Carlos D Hunter Bartlett C Hamilton 3rd Amy L DeVeney Mary M Huerter Lynell W Klassen Geoffrey M Thiele 2009World Journal of Gastroenterology2009,15,10:20
2The role of catalysis in the design, development and implementation green chemistry 显示文摘Anastas P T Bartlett L B Kirchhoff M M 2000Catalysis Today2000,55,:2
3Intracellular Hmgb1 Inhibits Inflammatory Nucleosome Release and Limits Acute Pancreatitis in Mice显示文摘Rui Kang Qiuhong Zhang Wen Hou Zhenwen Yan Ruochan Chen Jillian Bonaroti Preeti Bansal Timothy R. Billiar Allan Tsung Qingde Wang David L. Bartlett David C. Whitcomb Eugene B. Chang Xiaorong Zhu Haichao Wang Ben Lu Kevin J. Tracey Lizhi Cao Xue-Gong Fan M 2013Gastroenterology2013,,:2
4Load Factor Calibration for the Proposed 2005 Edition of the National Building Code for Canada: Companion-action Load Combinations 显示文摘Bartlett F M Hong H P Zhou W 2003Canadian Journal of Civil Engineering2003,,30:1
5Classifying facial actions显示文摘Donato G Bartlett M S Hager J C 1999IEEE Transactions on Pattern Analysis and Machine Intelligence1999,21,10:1
6Crizotinib for the treatment of ALK-rearranged non-smallcell lung cancer:a success story to usher in the seconddecade of molecular targeted therapy in oncology 显示文摘Ou S H Bartlett C H Mino-Kenudson M 2012TheOncologist2012,17,11:1
7Recommendations for HER-2 testing in the UK显示文摘Ellis IO Dowsett M Bartlett J 2000J Clin Pathol2000,53,12:1
8Using a neural network and spatial clustering to predict the location of active sites in enzymes显示文摘Gutteridge A Bartlett G J Thornton J M 2003Journal of Molecular Biology2003,330,4:1
9Application of machine learning in the fault diagnostics of air handling units显示文摘Najafi M Auslander D M Bartlett P L 2012Applied Energy2012,96,:1
10The Strobilurin Fungicides 显示文摘BARTLETT D W CLOUGH J M GODWIN J R 2002Pest Manag Sci2002,58,:1
11Face recognition by independent component analysis显示文摘 Movellan J R Sejnowski T J 2002IEEE Transactions on Neural Networks2002,13,6:1
12Guidelines for human epidermal growth factor receptor 2 testing:biologic and methodologic considerations显示文摘Sauter G Lee J Bartlett J M 2009J Clin Oncol2009,27,8:1
13Face recognition by ICA显示文摘Bartlett M S Movellan J R Sejnowski T J 2002IEEE Transactions on Neural Networks2002,13,6:1
14High-throughput Agrobacterium-mediated barley transformation 显示文摘Bartlett J G Aires S C Smedley M 2008Plant Method2008,4,:1
15Recognizing faces with PCA and ICA显示文摘Draper B A Baek K Bartlett M S 2003Computer Vision Image Understanding2003,91,1:1
16Guidelines for human epidermal growth factor receptor 2 testing: biologic and methodologic considerations显示文摘SAUTER G LEE J BARTLETT J M 2009J C/in Oncol2009,27,8:1
17Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia显示文摘Bartlett JG Chang TW Gurwith M 1978N Engl J Med1978,298,10:1
18Causes of death after diagnosis of hepatitis B or hepatitis C infection: a large community-based linkage study显示文摘Amin J Law MG Bartlett M 2006Lancet2006,368,:1
19Wetting of regularly structured gold surfaces显示文摘Abdelsalam M E Bartlett P N Kelf T 2005Langmuir2005,21,5:1
20Binary fission of pneumocystis carinii trophozoites grown in vitro 显示文摘Richardson JD Queener SF Bartlett M 1989J Protozool1989,36,1:1
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