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| 1 | Hypolipidemic and anti-atherosclerogenic effects of aqueous extract of Ipomoea batatas leaves in diet-induced hypercholesterolemic rats显示文摘Objective:Ipomoea batatas(L.)Lam.is a food plant used in African traditional medicine to treat cardiovascular diseases and related conditions.We assessed the hypolipidemic and anti-atherosclerogenic properties of the aqueous extract of I.batatas leaves in a rat model of diet-induced hypercholesterolemia.Methods:Hypercholesterolemia was induced in male Wistar rats by exclusive feeding with a cholesterolenriched(1%)standard diet for four weeks.Then,rats were treated once daily(per os)with I.batatas extract at doses of 400,500 and 600 mg/kg or with atorvastatin(2 mg/kg),for four weeks.Following treatment,animals were observed for another four weeks and then sacrificed.Aortas were excised and processed for histopathological studies,and blood glucose level and lipid profile were measured.Results:Hypercholesterolemic animals experienced a 21.5%faster increase in body weight,significant increases in blood glucose and blood lipids(148.94%triglycerides,196.97%high-density lipoprotein cholesterol,773.04%low-density lipoprotein cholesterol,148.93%very low-density lipoprotein cholesterol and 210.42%total cholesterol),and increases in aorta thickness and atherosclerotic plaque sizes compared to rats fed standard diet.Treatment of hypercholesterolemic rats with the extract mitigated these alterations and restored blood glucose and blood lipid levels to normocholesterolemic values.Conclusion:Our findings suggest that I.batatas leaves have hypolipidemic and anti-atherosclerogenic properties and justify their use in traditional medicine. | Fidele Ntchapda Fernand C.Tchatchouang David Miaffo Barthelemy Maidadi Lorella Vecchio Rodrigue E.Talla Christian Bonabe Paul F.Seke Etet Theophile Dimo | 2021 | Journal of Integrative Medicine2021，19，3： | 2 |
| 2 | Cryopreservation of spermatozoa : a ! 996 review显示文摘 | Royere D Barthelemy C Hamamah S | 1996 | Hum Reprod Update1996，2，6： | 1 |
| 3 | The median procedure for partitions显示文摘 | BARTHELEMY J LECLERC B | 2008 | DIMACS Series in Discrete Mathematics2008，41，10： | 1 |
| 4 | Modelling and measurements of wakes in large wind farms显示文摘 | BARTHELEMIE R J RATHMANN O FRANDSEN S T | | 0，，： | 1 |
| 5 | Long-distance coherent coupling in a quantum dot array 显示文摘 | Braakman F R Barthelemy P Reichl C | 2013 | Nature Nanotechnology2013，8，： | 1 |
| 6 | Betweenness centrality in large complex networks 显示文摘 | Barthelemy M | 2004 | Eur Phys J B2004，38，2： | 1 |
| 7 | Complexity of outsourcing contracts and ex-post transaction costs: An empirical investigation显示文摘 | BARTHELEMY J QUELIN B V | 2006 | Journal of Management Studies2006，48，4： | 1 |
| 8 | Resolution Limit in Community Detection显示文摘 | Fortunato S Barthelemy M | 2007 | PNAS2007，104，1： | 1 |
| 9 | Resolution limit in community detection显示文摘 | Fortunato S Barthelemy M | 2007 | Proc Natl Acad Sci USA2007，104，1： | 1 |
| 10 | Cryopreservation of spermatozoa:a 1996 review显示文摘 | Royere D Barthelemy C Hamamah S | 1996 | Hum Reprod Update1996，2，6： | 1 |
| 11 | Classes of small- world networks显示文摘 | Amaral LA Scala A Barthelemy M | 2000 | Proc Natl Acad Sci USA2000，97，11： | 1 |
| 12 | Large-scale cross-correlations in Internet traffic 显示文摘 | Barthelemy M Gondran B Guichard E | 2002 | Physical Review E2002，66，9： | 1 |
| 13 | Architecture of complex weighted networks 显示文摘 | Barrat A Barthelemy M Pastor-Satorras R et at | 2004 | Pnas2004，11，： | 1 |
| 14 | Highly stable 68 fs pulse generation from a stretched-pulse Yb^3+ -doped fiberlaser with frequency shifted feedback显示文摘 | Albert A Couderc V Barthelemy A | 2002 | IEEE Photonics Technology Letters2002，14，12： | 1 |
| 15 | Effects of curcumin derivatives on mitochondrial permeability transition pore显示文摘 | Ligeret H Barthelemy S Zini R etal | 2004 | Free Radic Biol Med2004，36，1： | 1 |
| 16 | 显示文摘 | Barthelemy A | 2002 | J Magn Magn Mater2002，24，： | 1 |
| 17 | Obstructive sleep apnea and the metabolic syndrome in an elderly healthy population: the SYNAPSE cohort显示文摘 | Hourfil-Gabin Assoumou Jean-Michel Gaspoz Emilia Sforza Vincent Pichot Sébastien Celle Delphine Maudoux Michel Kossovsky Florian Chouchou Jean-Claude Barthelemy Frédéric Roche | 2012 | Sleep and Breathing2012，，3： | 1 |
| 18 | Long -term sealing ability of Pulp Canal Sealer, AH -Plus, GuttaFlow and Epiphany 显示文摘 | Bouillaguet S Shaw L Barthelemy J | 2008 | Int Endod J2008，41，3： | 1 |
| 19 | Small-world networks:Evidence for a crossover picture显示文摘 | Barthelemy M Amaral L A N | 1999 | Physical Review Letters1999，，82： | 1 |
| 20 | Two point exponential approximation method for structural optimization 显示文摘 | Fadel G M Riley M F Barthelemy J M | 1990 | Structural Optimization1990，2，： | 1 |
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