|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Blood glucose changes surrounding initiation of tumor-necrosis factor inhibitors and conventional disease-modifying anti-rheumatic drugs in veterans with rheumatoid arthritis显示文摘AIM To determine the scope of acute hypoglycemic effects for certain anti-rheumatic medications in a large retrospective observational study. METHODS Patients enrolled in the Veterans Affairs Rheumatoid Arthritis (VARA) registry were selected who, during follow-up, initiated treatment with tumor necrosis factor inhibitors (TNFi's, including etanercept, adalimumab, infliximab, golimumab, or certolizumab), prednisone, or conventional disease-modifying anti-rheumatic drugs(DMARDs), and for whom proximate random blood glucose (RBG) measurements were available within a window 2-wk prior to, and 6 mo following, medication initiation. Similar data were obtained for patients with proximate values available for glycosylated hemoglobin A1C values within a window 2 mo preceding, and 12 mo following, medication initiation. RBG and A1C measurements were compared before and after initiation events using paired t-tests, and multivariate regression analysis was performed including established comorbidities and demographics.RESULTS Two thousands one hundred and eleven patients contributed at least one proximate measurement surrounding the initiation of any examined medication. A significant decrease in RBG was noted surrounding 653 individual hydroxychloroquine-initiation events(-3.68 mg/dL, P = 0.04), while an increase was noted for RBG surrounding 665 prednisone-initiation events(+5.85 mg/d L, P < 0.01). A statistically significant decrease in A1C was noted for sulfasalazine initiation, as measured by 49 individual initiation events(-0.70%, P < 0.01). Multivariate regression analyses, using methotrexate as the referent, suggest sulfasalazine (β =-0.58, P = 0.01) and hydroxychloroquine(β =-5.78, P = 0.01) use as predictors of lower post-medicationinitiation RBG and A1C values, respectively. Analysis by drug class suggested prednisone (or glucocorticoids) as predictive of higher medication-initiation event RBG among all start events as compared to DMARDs, while this analysis did not show any drug class-level effect for TNFi. A diagnosis of congestive heart failure(β = 4.69, P = 0.03) was predictive for higher post-initiation RBG values among all medication-initiation events.CONCLUSION No statistically significant hypoglycemic effects surrounding TNFi initiation were observed in this large cohort. Sulfasalazine and hydroxychloroquine may have epidemiologically significant acute hypoglycemic effects. | Patrick R Wood Evan Manning Joshua F Baker Bryant England Lisa Davis Grant W Cannon Ted R Mikuls Liron Caplan | 2018 | World Journal of Diabetes2018，9，2： | 8 |
| 2 | The injury severity score : a method for describing patients with multiple injuries and evaluating emergency care 显示文摘 | Baker SP O heill B Haddon W Jr | 1974 | J Trauma1974，14，3： | 3 |
| 3 | Assessment of the Progress of the Back-Pain Patient显示文摘 | R MILLION W HALL K HAAVIK NILSEN R D BAKER M I V JAYSON | 1982 | Spine1982，，3： | 2 |
| 4 | An evaluation of the quantitative and radiation features of a scanning X-ray transverse axial tomograph:The EMI scanner显示文摘 | McCullough E C Baker H L House O W | 1974 | Radiat Phys1974，111，3： | 2 |
| 5 | Lidar-measured winds from space: a key component for weather and climate prediction 显示文摘 | BAKER W E EMMITT G D ROBERTSON F | 1995 | Bulletin of the American Meteorological Society1995，76，6： | 1 |
| 6 | Basic functionalization of polyethylene in the melt 显示文摘 | Simons A Baker W E | 1989 | Polymer Engineering and Science1989，29，： | 1 |
| 7 | Price Smarter on The Net显示文摘 | Baker W Marn M Zawada C | 2001 | Harvard Business Review2001，27，： | 1 |
| 8 | Investor Sentiment and the Cross-section of Stock Returns显示文摘 | BAKER M JEFFREY W | 2006 | The Journal of Finance2006，61，4： | 1 |
| 9 | The effect of sward height on ball roll properties for Association Football 显示文摘 | Richards C W Baker S W | 1992 | Journal of the sports turf research institute1992，，68： | 1 |
| 10 | Calibration Precision of Capacitance and Neutron Soil Water Content Gauges in Arid Soils显示文摘 | WAUGH W J BAKER D A KASTENS M K | 1996 | Arid Soil Research and Rehabilitation1996，10，： | 1 |
| 11 | Polyolefin/Polystyrene In Situ Compatibilization Using Fridel-Crafts Alkylation 显示文摘 | Jun S Y Baker W E | 1997 | J Appl Polym Sci1997，65，： | 1 |
| 12 | ACC /AHA guidelines for the evaluation and management of chronic heart failure in the adult:executive summary:a report of the American College of Cardiology/American Heart Association task force on practice guidelines(committee to revise the 1995 guidelines for the evaluation and management of heart failure)显示文摘 | HUNT S A BAKER D W CHIN M H | 2001 | Circulation2001，104，： | 1 |
| 13 | The injury severity score:a method for describing patients with multiple injuries and evaluating emergency care显示文摘 | Baker SP O'Neill B Haddon W | 1974 | J Trauma1974，14，： | 1 |
| 14 | How to find a permanent solution to your compaction and drainage problems 显示文摘 | BAKER S W | 1982 | Turf Management1982，1，6： | 1 |
| 15 | ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Aduh: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 Guidelines for the Evaluation and Management of Heart Failure): Developed in Collaboration with the International Society for Heart and Lung Transplantation; Endorsed by the Heart Failure Society of America 显示文摘 | HUNT S A BAKER D W CHIN M H | 2001 | Circulation2001，104，24： | 1 |
| 16 | The synergistic effect of mar- ket orientation and learning orientation on organizational performance显示文摘 | Baker W E Sinkula J M | 1999 | Journal of the Academy of Marketing Science1999，27，4： | 1 |
| 17 | Harpin, an elicitor of the hypersensitive response in tobacco caused by Erwinia amylovora, elicits active oxygen production in suspension cells 显示文摘 | BAKER C J ORLANDI E W MOCK N M | 1993 | Plant Physiology1993，102，： | 1 |
| 18 | The sensitivity of West African convective line water budgets to land cover显示文摘 | MOHR K I BAKER R D TAO W K | 2003 | J Hydrometeor2003，4，1： | 1 |
| 19 | Tennlnal B-cell matura- tion and immunoglobulin synthesis in vitro in patients with major in jury显示文摘 | FAIST E ERTEL W BAKER CC | 1989 | Trauma1989，，29： | 1 |
| 20 | Nicorandil-indueed severe perianal ulceration 显示文摘 | Baker RP A1-Kubati W Atuf M | 2007 | Teeh Coloproctol2007，11，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员