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| 1 | Seismic failure mode improvement of RC frame structure based on multiple lateral load patterns of pushover analyses显示文摘The structural failure under severe ground motions is primarily caused by their unreasonable seismic failure mode (SFM). This paper provides a methodology aiming at the SFM improvement of reinforced concrete frame structure. An RC frame is modeled and three types of failure criterion are defined as the premise of SFM. Static pushover analysis is adopted to identify the SFM. The dominant failure modes and failure paths of the structure are obtained in three lateral load patterns (inverted trian- gular distribution, uniform distribution and adaptive distribution). Based on the pushover analysis, the sequential failure of components and the probability of the occurrence of plastic hinges are determined. By this, weak components of the structure are detected and herein are strengthened. The project cost of the proposed strengthening strategy increases by 2.4%. Capacity spectrum method is used to study the performance of the strengthening structure. Pushover analysis is conducted again to present the improvement of strength and ductility. Lateral drift and local response through IDA are also studied to indicate that the strengthening of some columns and beams can improve the SFM to enhance the seismic capacity of structure. | BAI JiuLin OU JinPing | 2011 | Science China(Technological Sciences)2011，54，11： | 14 |
| 2 | Realization of the global yield mechanism of RC frame structures by redesigning the columns using column tree method显示文摘Global failure mechanism, i.e., the strong-column weak-beam mechanism, can provide higher total energy dissipation capacity with less ductility demand on components than other failure modes, and results in a more uniform story drift distribution and higher resistance to earthquake loads at the system level. However, the current code-based elastic design method cannot guarantee the global failure mechanism of frame structures under severe earthquakes. In this paper, a simple, but practical design procedure is proposed to ensure the global failure mechanism of reinforced concrete(RC) frame structures by redesigning the columns using the column tree method(CTM). CTM considers the yield limit state of all beams and column bases. The code-based design is firstly carried out to determine the section information of all beams and base columns. Then, the internal force demands applied on the column tree can be derived. Lastly, the column moments, shear forces and axial forces are determined according to the free-body diagram of CTM to finish the column redesign. Two RC frame structures with 6 and 12 stories are illustrated to verify the design procedure. The analytical results demonstrate the proposed approach can realize the global failure mechanism. | BAI JiuLin OU JinPing | 2015 | Science China(Technological Sciences)2015，58，10： | 2 |
| 3 | Scale effect and methods for accuracy evaluation of attribute information loss in rasterization显示文摘Rasterization 是伴有信息损失的一个变换过程,它包括特征形状的损失,结构,位置,属性等等。假装在 rasterization 估计属性精确性损失的二个主要因素是格子房间尺寸和评估方法。也就是说,在 rasterization 的属性精确性损失与格子房间尺寸有一种靠近的关系;而且,它被评估方法也影响。因此,分析这二是重要的包括地影响因素。作为一个盒子在 2005 在 1:250,000 的规模拿四川的陆地盖子数据,鉴于数据体积和它学习区域的处理时间,这研究从 600 m 选择 16 空间规模到 30 km ,在 ArcGIS 和属性精确性损失的二评估方法基于最大的区域( RMA )的规则使用 rasterizing 方法,它是正常分析方法( NAM )和分别地,基于格子房间( MBGC )的一个新方法并且分析属性的规模效果(它是这里的区域)在 1 点的精确性损失结果显示出那:(1 ) 在一样可伸缩, MBGC 评估的全部学习区域的平均区域精确性损失比用 NAM 估计的那显著地大。而且,在二之间的这差异在到 10 km 的 1 km 的范围是明显的。当格子房间比 10 km 大时,平均区域精确性损失在二计算了评估方法是稳定的,甚至趋于到平行。(2 ) MBGC 不能仅仅精确地估计 RMA rasterization 属性精确性损失,但是能客观地表示损失的空间分发。( 3 )为在在 2005 的 1:250,000 的规模的四川的陆地盖子数据的 RMA rasterization 的合适的规模域更好平等者到或不到 800 m ,数据卷在是有利的和处理时间不太长,象区域精确性一样,损失是不到2.5%。 | BAI Yan LIAO Shunbao SUN Jiulin | 2011 | Journal of Geographical Sciences2011，21，6： | 2 |
| 4 | Long non-coding RNA HCAR promotes endochondral bone repair by upregulating VEGF and MMP13 in hypertrophic chondrocyte through sponging miR-15b-5p显示文摘Endochondral bone formation is an important route for bone repair.Although emerging evidence has revealed the functions of long non-coding RNAs(lncRNAs)in bone and cartilage development,the effect of lncRNAs in endochondral bone repair is still largely unknown.Here,we identified a lncRNA,named Hypertrophic Chondrocyte Angiogenesis-related lncRNA(HCAR),and proved it to promote the endochondral bone repair by upregulating the expression of matrix metallopeptidase 13(Mmp13)and vascular endothelial growth factorα(Vegfa)in hypertrophic chondrocytes.Lnc-HCAR knockdown in hypertrophic chondrocytes restrained the cartilage matrix remodeling and decrease the CD31hiEmcnhi vessels number in a bone repair model.Mechanistically,we proved that lnc-HCAR was mainly enriched in the cytoplasm using fluorescence in situ hybridization(FISH)assay,and it acted as a molecular sponge for miR-15b-5p.Further,in hypertrophic chondrocytes,lnc-HCAR competitively bound to miR-15b-5p to increase Vegfa and Mmp13 expression.Our results proved that lncRNA is deeply involved in endochondral bone repair,which will provide a new theoretical basis for future strategies for promoting fracture healing. | Yun Bai Xiaoshan Gong Rui Dong Zhen Cao Ce Dou Chuan Liu Jianmei Li Fei Kang Jingjin Dai Chunrong Zhao Zhansone Tian Jiulin Tan Qijie Dai Shiwu Dong | 2022 | Genes & Diseases2022，9，2： | 1 |
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