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| 1 | Sonographic appearance of anal cushions of hemorrhoids显示文摘AIM To evaluate the diagnostic value of different sonographic methods in hemorrhoids.METHODSForty-two healthy volunteers and sixty-two patients with gradesⅠ-Ⅳhemorrhoids received two different sonographic examinations from January 2013 to January2016 at the First and Second Hospitals of Xinjiang Medical University in a prospective way.We analyzed the ultrasonographic findings of these participants and evaluated the outcomes.Resected gradesⅢandⅣhemorrhoid tissues were pathologically examined.The concordance of ultrasonographic results with pathologyresults was assessed with the Cohen’s kappa coefficient.RESULTS All healthy volunteers and all patients had no particular complications related to sonography.There were no statistically significant differences between the participants regarding age(P=0.5919),gender(P=0.4183),and persistent symptoms(P>0.8692).All healthy control participants had nospecial findings.However,30 patients with hemorrhoids showed blood signals around the dentate line on ultrasonography.When gradesⅠandⅡhemorrhoids were analyzed,there were no significant differences between transrectal ultrasound(TRUS),transperianal ultrasound(TPUS),and transvaginal ultrasound(TVUS)(P>0.05).GradesⅢandⅣhemorrhoids revealed blood flow with different directions which could be observed as a'mosaic pattern'.In patients with gradesⅢandⅣhemorrhoids,the number of patients with'mosaic pattern'as revealed by TRUS,TPUS and TVUS was 22,12,and 4,respectively.Patients with gradesⅢandⅣdisease presented with a pathologically abnormal cushion which usually appeared as a'mosaic pattern'in TPUS and an arteriovenous fistula in pathology.Subepithelial vessels of resected gradesⅢandⅣhemorrhoid tissues were manifested by obvious structural impairment and retrograde and ruptured changes of internal elastic lamina.Some parts of the Trietz’s muscle showed hypertrophy and distortion.Arteriovenous fistulas and venous dilatation were obvious in the anal cushion of hemorhoidal tissues.After pathological results with arteriovenous fistulas were taken as the standard reference,we evaluated the compatibility between the two methods according to the Cohen’s kappa coefficiency calculation.The compatibility(Cohein kappa co-efficiency value)between'mosaic pattern'in the TPUS and arteriovenous fistula in pathology was very good(?=0.8939).When compared between different groups,TRUS presented the advantage that the mosaic pattern could be confirmed in more patients,especially for group A.There was a statistical difference when comparing group A with group B or C(P<0.05 for both).There were obvious statistical differences between group A and group B with regard to the vessel diameter and blood flow velocity measured by TRUS(P<0.05).CONCLUSION Patients with gradesⅢandⅣhemorrhoids present with a pathologically abnormal cushion which usually appears as a'mosaic pattern'in sonography,which is in accord with an arteriovenous fistula in pathology.There are clearly different hemorrhoid structures shown by sonography.'Mosaic pattern'may be a parameter for surgical indication of gradesⅢandⅣhemorrhoids. | Adilijiang Aimaiti Ma Mu Ti Jiang A Ba Bai Ke Re Irshat Ibrahim Hui Chen Maimaitituerxun Tuerdi Mayinuer | 2017 | World Journal of Gastroenterology2017，23，20： | 11 |
| 2 | Influence of IFNα-2b and BCG on the release of TNF and IL-1 by Kupffer cells in rats with hepatoma显示文摘INTRODUCTIONKupffer cells are residential macrophages in the liver ,which play a critical role in the maintenance of normal liver function and in immunal surveilance of hepatocellular carcinoma (HCC) and other cancers[1].The biological immune modulants have cancers[2].In our previous studies ,the combined use of biological immune modulants showed better dffects . | Xian Yong Bai~1 Xiu Hong Jia~2 Ling Zhong Cheng~3 Yun Di Gu~3 ~1Department of Histology and Embryology,Binzhou Medical College,Binzhou 256603,Shandong Province,China ~2Departrnent of Pediatrics,Binzhou Medical College,Binzhou 256603,Shandong Province,China ~3Department of Histology and Embryology,Shanghai Medical University,Shanghai 200032,ChinaDr.Xian Yong Bai graduated from the Shanghai Medical University as a postgraduate in 1995,Professor of Histology and Embryology,specialized in hepatic tumor immunology,having 36 papers published. | 2001 | World Journal of Gastroenterology2001，7，3： | 7 |
| 3 | Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1显示文摘聚合酶我和抄本版本因素(PTRF,也作为 Cavin-1 知道) 是在 caveolae 的生物的续生说和功能的一个必要部件。这里,我们证明那 PTRF 表情在衰老的人的成纤维细胞被增加。重要地, PTRF 的 overexpression 导致了细胞的老朽特征的特征,而减少的 PTRF 表示扩大了细胞的 replicative lifespan。有趣地,我们在细胞的老朽期间首先发现那 PTRF 局部性到年轻、静止的 WI-38 人的成纤维细胞,而是 translocated 的原子核到 cytosol 和血浆膜。而且,显微镜的分析表明了的电子 caveolar 结构在的一个增加的数字衰老并且 PTRF-transfected WI-38 房间。我们的数据建议在细胞的老朽的 PTRF 的角色依赖于它指向到有 caveolin-1 的 caveolae 和它的相互作用,它看起来被 PTRF 的 phosphorylation 调整。一起拿,我们的调查结果作为通过 p53/p21 和 caveolar 小径行动的细胞的老朽的一个新奇管理者识别 PTRF。 | Lin Bai Xiaoli Deng Juanjuan Li Miao Wang Qian Li Wei An Deli A Yu-Sheng Cong | 2011 | Cell Research2011，21，7： | 5 |
| 4 | JWA regulates melanoma metastasis by integrin alpha(V)beta(3) signaling(摘要)显示文摘 | Bai, J Zhang, J Wu, J Shen, L Zeng, J Ding, J Wu, Y Gong, Z Li, A Xu, S Zhou, J Li, G | 2010 | 南京医科大学学报(自然科学版)2010，30，8： | 4 |
| 5 | Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects. | Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai | 2010 | World Journal of Gastroenterology2010，16，25： | 4 |
| 6 | Scattering of guided waves by circumferential cracks in steel pipes显示文摘 | Bai H Shah A H Popplewell N | 2001 | Trans ASME J of Appl Mech2001，68，4： | 2 |
| 7 | Protective effect and mechanisms of action of Mongolian medicine Sulongga-4 on pyloric ligation-induced gastroduodenal ulcer in rats显示文摘BACKGROUND Sulongga-4(SL-4)is a herbal formula used in traditional Mongolian medical clinics for the treatment of peptic ulcers and gastroenteritis,even though its pharmacological mechanism has not been well characterized.AIM To evaluate the protective effect and identify the mechanisms of action of SL-4 on gastroduodenal ulcer induced by pyloric ligation(PL)in rats.METHODS PL was performed to induce gastric and duodenal ulcers in rats,which were then treated with oral SL-4(1.3,2.6,or 3.9 g/kg per day)for 15 d.PL-induced gastroduodenal ulceration.Therapeutic effects were characterized by pathological and histological evaluations and inflammatory indicators were analyzed by enzyme-linked immunosorbent assay.Microarray analyses were conducted to identify gene expression profiles of gastroduodenal tissue in PL rats with or without SL-4 treatment.The candidate target genes were selected and verified by quantitative reverse transcription polymerase chain reaction(qRT-PCR).RESULTS SL-4 decreased histopathological features in the PL-induced ulcerated rats.SL-4 significantly (P < 0.05) decreased expression of tumor necrosis factor-α,interleukin (IL)-1β, IL-6, endotoxin, platelet-activating factor, and increasedprostaglandin E2 and epidermal growth factor in ulcer tissue. Microarray analysiswas used to identify a panel of candidate target genes for SL-4 acting on PLinducedulceration. Genes included some complement and coagulation cascadeand retinol metabolism pathways that are closely associated with inflammatoryresponses and gastric mucosal protective mechanisms. qRT-PCR showed thataltered expression of the selected genes, such as CYP2b2, UGT2b1, A2m, andMASP1 was consistent with the microarray results.CONCLUSIONSL-4 exerts protective effects against PL-induced gastroduodenal ulcers viareducing inflammatory cytokines and elevating expression of gastric acidinhibitory factors. Downregulation of CYP2b2 and UGT2b1 genes in retinolmetabolism and upregulation of A2m and MASP1 genes in the complement andcoagulation cascades pathways are possibly involved in SL-4-mediated protectionagainst gastroduodenal ulcer. | Shan Tong Huan Wang Li-Sha A Ta-Na Bai Ju-Hua Gong Wen-Jie Jin Li-Li Dai Gen-Na Ba Sung-Bo Cho Ming-Hai Fu | 2021 | World Journal of Gastroenterology2021，27，16： | 2 |
| 8 | HPRS-103 (exogenous avian leukosis virus, subgroup J) has an env related to those of endogenous elements EAV-0 and E51 and E element found previously only in sarcoma virus显示文摘 | BAI J PAYNE L N SKINNER M A | 1995 | J Wirol1995，69，2： | 1 |
| 9 | YAG laser percussion drilling of a functional multi-layer thin plate 显示文摘 | WANG A H WANG W Y BAI Z K XIE C S ZENG D W SONG W L | 2007 | Optics & Laser Technology2007，39，： | 1 |
| 10 | Proposed nomenclature for quantify-ing subdivisions of the bronchial wall显示文摘 | Bai A Eidelman D H Hogg J C | 1994 | J Appl Physiol1994，77，2： | 1 |
| 11 | Membrane fouling and cleaning in microfiltration of activated sludge wastewater显示文摘 | Lim A L Bai R | 2003 | J Membr Sci2003，216，： | 1 |
| 12 | Gender differences and age-related white matter changes of the human brain: a diffu- sion tensor imaging study 显示文摘 | Hsu JL Leemans A Bai CH | 2008 | Neuroimage2008，39，2： | 1 |
| 13 | All-trans retinoie acid down-regulates inflammatory responses by shifting the Treg/Thl7 profile in human ulcerative and murine colitis显示文摘 | Bai A Lu N Guo Y | 2009 | J Lenkoc Biol2009，86，4： | 1 |
| 14 | Everolimus for previous- ly treated advanced gastric eaneer:resuhs of the randomized, double-blind,phase Ⅲ GRANITE-1 study 显示文摘 | Ohtsu A Ajani JA Bai YX | | J Clin On- col0，31，31： | 1 |
| 15 | The Theoretical Analysis on The Allocation of Ur- ban Resources Based On Agglomeration Economies显示文摘 | tWang P A Bai Y P | 2012 | Advances in Intelligent and Soft Computing2012，，： | 1 |
| 16 | Lung cancer risk in the electroplating industry in Lombardy,Italy,using the Italian occupational cancer monitoring(OCCAM)information system显示文摘 | Panizza C Bai E Oddone E Scaburri A | 2012 | Am J Ind Med2012，55，1： | 1 |
| 17 | Jitter performance in Ethemet passive optical networks显示文摘 | SHAMI A BAI XIAOFENG ASSI C M | 2005 | Journal of Lightwave Technology2005，23，4： | 1 |
| 18 | Changes in biologically-active ultraviolet radiation reaching the Earth's surface 显示文摘 | McKenzie R L Aucamp P J Bais A F | 2007 | Photochemical and Photobiological Sciences2007，6，3： | 1 |
| 19 | Mechanical and electrical properties of a MWNT/epoxy composite 显示文摘 | Allaoui A Bai S Cheng H M | 2002 | Composites Science and Technology2002，62，15： | 1 |
| 20 | Modeling path duration distributions in MANETs and their impact on reactive routing protocols 显示文摘 | Bai F N Sadagopan B Krishnamachari A Helmy | 2004 | IEEE Journal on Selected Areas in Communications: (S0733-8716)2004，22，7： | 1 |
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