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| 1 | Quality of life after curative liver resection: A single center analysis显示文摘AIM: To evaluate quality of life (QoL) after curative liver resection and identify variables associated with decreased QoL. METHODS: From October 2001 to July 2004, 323 patients underwent liver resection. At 3-36 mo after discharge, 188 patients were disease free. QoL was assessed using the Short Form (SF)-12 Health Survey with mental and physical component scales (SF-12 MCS and PCS), supplemented with generic questions concerning pain and liver-specific items. RESULTS: Sixty-eight percent (128/188) returned the questionnaire, which was completed in 75% (96/128) of cases. Median SF-12 PCS and MCS were 46.7 (inter- quartile range: 34.2-53.9) and 54.1 (42.8-58.2). Fifty percent were pain free with a median symptom score of 1.75 (1.38-2.13). PCS was higher after major hepatec-tomy [57% (55/96)] compared to minor resection (P = 0.0049), which represented an improved QoL. QoL was not affected by sex but by age compared to the general German population. MCS was higher after liver surgery for metastatic disease [55.9 (47.5-58.8)] compared to primary carcinoma [49.6 (36.5-55.1)] and benign disease [49.2 (37.7-56.3)] (P = 0.0317). There was no correlation between length of postoperative period and QoL. Pain, def iciencies in everyday life and a high symptom score significantly decreased MCS and PCS. CONCLUSION: Most patients were only marginally affected even after major liver resection; however, minor complications were associated with decreased SF-12 MCS and PCS and need careful attention. | Helge Bruns Kirsten Krtschmer Ulf Hinz Anette Brechtel Monika Keller Markus W Büchler Peter Schemmer | 2010 | World Journal of Gastroenterology2010，16，19： | 2 |
| 2 | Specific abrogation of transforming growth factorbeta signaling in T cells alters atherosclerotic lesion size and composition in mice显示文摘 | Gojova A Brun V Esposito B | 2007 | Blood2007，102，12： | 1 |
| 3 | Expression of MMP-2, -7,-9,MT1 -MMP and TIMP -1 and -2 has no prognostic relevance inpatients with advanced epithelial ovarian cancer 显示文摘 | Brun JL Cortez A Lesieur B | 2012 | Oncol Rep2012，27，4： | 1 |
| 4 | The APACHE II score is unreliable to diagnose necrotizing pancreatitis on admission to hospital显示文摘 | Lankisch PG Warnecke B Bruns D | 2002 | Pancreas2002，24，3： | 1 |
| 5 | Differential activation of adipogenesis by multiple PPAR isoforms显示文摘 | Brun R P Tontonoz P Forman B M | 1996 | Genes Dev1996，，10： | 1 |
| 6 | CT in retroperitoneal fibrosis显示文摘 | Brun B Laursen K Sorensen IN | | 0，，03： | 1 |
| 7 | Strategies for insulin initiation: insights from the French LIGHT observational study显示文摘 | Verges B Brun JM Tawil C | 2012 | Diabetes Metab Res Rev2012，28，： | 1 |
| 8 | Cloud based infrastructure, the new business possibilities and barriers显示文摘 | Christian Kloch Ebbe B Petersen and Ole Brun Madsen | 2011 | Wireless Personal Communitions2011，58，1： | 1 |
| 9 | Expression of MMP-2,-7,-9,MT1-MMP and TIMP-1 and-2 has no prognostic relevance in patients with advanced epithelial ovarian cancer显示文摘 | Brun JL Cortez A Lesieur B | 2012 | Oncol Rep2012，27，4： | 1 |
| 10 | Leukocyte-derived interleukin 10 is required for protection against atherosclerosis in low-density lipoprotein receptor knockout mice显示文摘 | Potteaux S Esposito B van Oostrom O Brun V Ardouin P Groux H | 2004 | Arterioscler Thromb Vasc Biol2004，24，8： | 1 |
| 11 | Functional dyspepsia显示文摘 | Brun R Kuo B | | 0，，03： | 1 |
| 12 | High-throughput genotyping robot-assisted method for mutation detection in patients with hypertrophic cardiomyopathy显示文摘 | Bortot B Athanasakis E Brun F | 2011 | Diagn Mol Pathol2011，20，： | 1 |
| 13 | Laser velocimeter measurements in the pump of an automotive torque converter part II - effect of pump speed and oil viscosity显示文摘 | FLACK R D AINLEY S B BRUN K | 2000 | International Journal of Rotating Machinery2000，6，3： | 1 |
| 14 | Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus (Position Statement)显示文摘 | Sacks D B Bruns D E Goldstein D E | 2002 | Diabetes Care2002，25，： | 1 |
| 15 | Optimum design of cutouts in laminated composite structures 显示文摘 | Vellaichamy S Prakash B G Brun S | 1990 | Computers & Structures1990，37，3： | 1 |
| 16 | New insight into the pathogenesis of sepsis and the sepsis syndrome 显示文摘 | Johnson GB Brun GJ Samstein B | 2005 | Surgery2005，137，： | 1 |
| 17 | Improving the use of human milk during and after the NICU stay显示文摘 | Meier PP Engstrom JL Patel AL Jegier B J Bruns NE | 2010 | Clin Perinatol2010，37，1： | 1 |
| 18 | A new flavonol glycoside from Catha- ranthus roseus 显示文摘 | Brun G Dijoux M G David B | 1999 | Phytochemistry1999，50，1： | 1 |
| 19 | Laboratory experiments on sequential scour/ deposition and their application to the development of banded vege- tation 显示文摘 | Bryan R B Brun S E | 1999 | Catena1999，37，12： | 1 |
| 20 | Acute retinal necrosis: clinicalfeatures, early vitrectomy, andoutcomes 显示文摘 | Hillenkamp J Nalle B Bruns C | 2009 | Ophthalmology2009，116，10： | 1 |
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