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| 1 | Coupled modeling of tumour angiogenesis, tumour growth,and blood perfusion显示文摘This paper proposes a more realistic mathematical simulation method to investigate the dynamic process of tumour angio-genesis by fully coupling the vessel growth,tumour growth and associated blood perfusion.The tumour growth and angiogenesis are coupled by the chemical microenvironment and the cell-matrix interaction.The haemodynamic calculation is carried out on the new vasculature,and an estimation of vessel collapse is made according to the wall shear stress criterion.The results are consistent with physiological observations,and further confirm the application of the coupled model feedback mechanism.The model is available to examine the interactions between angiogenesis and tumour growth,to study the change in the dynamic process of chemical environment and the vessel remodeling. | Y.Cai,1,2 S.X.Xu,1,a) J.Wu,3 and Q.Long 2,b) 1) Department of Mechanics and Engineering Science,Fudan University,Shanghai 200433,China 2) Brunel Institute for Bioengineering,School of Engineering and Design,Brunel University,Uxbridge,Middlesex,UK 3) School of Naval Architecture,Ocean and Civil Engineering,Shanghai Jiaotong University,Shanghai 200240,China | 2011 | Theoretical & Applied Mechanics Letters2011，1，4： | 8 |
| 2 | STUDY ON WETLAND LOSS AND ITS REASONS IN CHINA显示文摘Wetlands are ecosystems with many f unctions.But the general public and government lack a comprehen-sive understanding of the importance of wetland benefits,thus making bl indly exploitation,wetland resour ces decreasing and losing biodiversity.So wetlands in China,as in most countries,have suffered heavily from the pressure o f develop-ment and have confronted with the thr eats of loss.The paper takes Sanjian g Plain marshes,lakes in the middle r eaches of the Changjiang(Yangtze)River,coastal wetlands and mangroves as cases to study wetland loss in China,and puts forward main existing reasons of wetland loss,such as blindly reclamati on and exploitation of wetland resou rces,over-exploitation of bio-resource s in wetland,etc.More recently,there has been a growing recognition of t he benefits of wetlands and a wide range of legal and regulatory initiatives have been undertaken which are designed to impro ve wetland management and conservation.On the basis of the above analysis,the paper brings forward some suggestions on wetland conservation. | HE Yan 1 ,ZHANG Ming-xiang 2,3 (1.The Chinese Academy of Sciences,B eijing 100864,P.R.China 2.Changchun Institute of Geography,the Chinese Academy of Sciences,Changchun 130021,P.R.China 3.Wetland Resources Monitoring Center,State Forestry Admi | 2001 | Chinese Geographical Science2001，11，3： | 5 |
| 3 | Thiol regulation of the production of TNF-alpha,IL-fi and IL-8 by human alveolar macrophages显示文摘 | 3 Gossetp Wallaert B Tonnel AB | 1999 | Eur Respir J1999，14，1： | 1 |
| 4 | Study of N-n-butyl-N-(2-nitroxyethyl)nitramine in RDX based gun propellant显示文摘 | Damse R S Omprakash B Tope B (3 | 2009 | Journal of Hazardous Materials2009，167，123： | 1 |
| 5 | A Fluid percussion model of experimental brain injury in the rat显示文摘 | DIXON C E LYETH B (3 POVLISHOCK J T | 1987 | J Neurosurg1987，67，1： | 1 |
| 6 | Prognosis of energetic compounds stability in solid phase 显示文摘 | Manelis G B Nazin G M Prokudin V (3 | 2009 | Centr Eur J Energet Ma- ter2009，6，1： | 1 |
| 7 | A two site enzyme linked imunosorbent assay μ for cytokeratin 8 显示文摘 | 3,Sundstrom B Stigbrand T | 1990 | Int J Cancer1990，46，60： | 1 |
| 8 | Changes in end plate vascul arity following an outer annulus tear显示文摘 | 3,Moore RJ Osti OL Vernon-Roberts B | 1992 | Spine,1992，17，3： | 1 |
| 9 | Automatic segmentation of hmg fields in chest radiographs 显示文摘 | Ginneken B V Romeny B 3' H | 2000 | MedPhys2000，27，10： | 1 |
| 10 | Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of cpg oligodeoxynucleotides显示文摘 | Brownlie R Zhu J Allan B and 3 others | | 0，，15： | 1 |
| 11 | Genetic epidemi-ological studies of early-onset deafness in the Schoolagepopuation显示文摘 | 3,Marazita ML,Ploughman L M Rawlings B | 1993 | Am J Med Genet1993，46，： | 1 |
| 12 | Highly photocatalytic ZnO/In203 heteronanostruetures synthesized by a coprecipitation method 显示文摘 | WANG Z Y HUANG B B DAI Y QIN X Y ZHANG X 3( WANG P LIU H X YU J X | 2009 | Journal of Physical Chemistry C2009，113，： | 1 |
| 13 | Removal of patho-genic and indicator microorganisms by a full-scale water recla-mation facility 显示文摘 | Rose J B Dickson L 3 Farrah S R | 1996 | J Water Research1996，30，11： | 1 |
| 14 | Kinetics of the thermal decomposition of n, n'-dinitropiperazine and 1,3- dinitro-1 , 3-diazacyclopentane 显示文摘 | Sitonina (3 V Korsoonskii B L Pyatakov N F | 1979 | Izv Akad Nauk 5SSR Ser Khim1979，，： | 1 |
| 15 | Plant Antifungal Proteins显示文摘 | 3,Dao J Y Ray A B Paul M H | 1996 | Plant Breeding Reviews1996，14，： | 1 |
| 16 | Nitrofurazone: reproductive assessment by continuous breeding in Swiss mice 显示文摘 | GEORGE 3 D FAIL P A GRIZZLE T B | 2007 | Fundamental and Applied Toxicology2007，34，1： | 1 |
| 17 | An epidemiologic study of lifting and twisting on the job and risk for acute prolapsed lumbar intervertebral disc显示文摘 | Kelsey J L Githens P B White A A 3 rd | 1984 | J Orthop Res1984，2，1： | 1 |
| 18 | An efficient simulator of 454 data using configurable statistical models 显示文摘 | Lysholm F Andersson B Persson ]3 | 2011 | BMC Re- search Notes2011，4，： | 1 |
| 19 | Wear resistance of laser - clad Ni - Cr - B - Si alloy on aluminium alloy 显示文摘 | Wong T 3' Liang G Y He B L | 2000 | Journal of Materials Processing Technology2000，100，1： | 1 |
| 20 | useful indicators of septic infections in severely traumatized patients,and 24-hour lactate clearance,in- terleukin-6,Early serum procalcitonin,World J Surg显示文摘 | Billeter A Turina M Seifert B et al 33 (3) | | 0，，： | 1 |
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