|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A high-density, multi-parental SNP genetic map on apple validates a new mapping approach for outcrossing species显示文摘Quantitative trait loci(QTL)mapping approaches rely on the correct ordering of molecular markers along the chromosomes,which can be obtained from genetic linkage maps or a reference genome sequence.For apple(Malus domestica Borkh),the genome sequence v1 and v2 could not meet this need;therefore,a novel approach was devised to develop a dense genetic linkage map,providing the most reliable marker-loci order for the highest possible number of markers.The approach was based on four strategies:(i)the use of multiple full-sib families,(ii)the reduction of missing information through the use of HaploBlocks and alternative calling procedures for single-nucleotide polymorphism(SNP)markers,(iii)the construction of a single backcross-type data set including all families,and(iv)a two-step map generation procedure based on the sequential inclusion of markers.The map comprises 15417 SNP markers,clustered in 3 K HaploBlock markers spanning 1267 cM,with an average distance between adjacent markers of 0.37 cM and a maximum distance of 3.29 cM.Moreover,chromosome 5 was oriented according to its homoeologous chromosome 10.This map was useful to improve the apple genome sequence,design the Axiom Apple 480 K SNP array and perform multifamily-based QTL studies.Its collinearity with the genome sequences v1 and v3 are reported.To our knowledge,this is the shortest published SNP map in apple,while including the largest number of markers,families and individuals.This result validates our methodology,proving its value for the construction of integrated linkage maps for any outbreeding species. | Erica A Di Pierro Luca Gianfranceschi Mario Di Guardo Herma JJ Koehorst-van Putten Johannes W Kruisselbrink Sara Longhi Michela Troggio Luca Bianco Hélène Muranty Giulia Pagliarani Stefano Tartarini Thomas Letschka Lidia Lozano Luis Larisa Garkava-Gustavsson Diego Micheletti Marco CAM Bink Roeland E Voorrips Ebrahimi Aziz Riccardo Velasco François Laurens W Eric van de Weg | 2016 | Horticulture Research2016，3，1： | 3 |
| 2 | Histopathological characteristics and causes of kidney graft failure in the current era of immunosuppression显示文摘BACKGROUND The histopathological findings on the failing kidney allograft in the modern era is not well studied. In this study, we present our experience working with kidney transplant recipients with graft failure within one year of the biopsy.AIM To report the histopathological characteristics of failed kidney allografts in the current era of immunosuppression based on the time after transplant, cause of the end-stage renal disease and induction immunosuppressive medications.METHODS In a single-center observational study, we characterized the histopathological findings of allograft biopsies in kidney transplant recipients with graft failure within one year after the biopsy.RESULTS We identified 329 patients with graft failure that met the selection criteria between January 1, 2006 and December 31, 2016. The three most common biopsy findings were interstitial fibrosis and tubular atrophy(IFTA, 53%), acute rejection (AR, 43%) and transplant glomerulopathy(TG, 33%). Similarly, the three most common causes of graft failure based on the primary diagnosis were AR(40%),TG(17%), and IFTA(13%). Most grafts failed within two years of post-transplant(36%). Subsequently, approximately 10%-15% of grafts failed every two years: >2-4 years(16%), > 4-6 years(13%), > 6-8 years(11%), > 8-10 years(9%) and > 10 years(16%). AR was the most common cause of graft failure in the first six years(48%), whereas TG was the most prevalent cause of graft failure after 6 years(32%) of transplant.CONCLUSION In the current era of immunosuppression, AR is still the most common cause of early graft failure, while TG is the most prevalent cause of late graft failure. | Sandesh Parajuli Fahad Aziz Neetika Garg Sarah E Panzer Emily Joachim Brenda Muth Maha Mohamed Justin Blazel Weixiong Zhong Brad C Astor Didier A Mandelbrot Arjang Djamali | 2019 | World Journal of Transplantation2019，9，6： | 2 |
| 3 | Cost-utility of 2 maintenance treatments for older adults with depression who responded to a course of electroconvulsive therapy:results from a decision analytic model显示文摘 | Aziz M Mehringer AM Mozurkewich E | 2005 | Can J Psychiatry2005，50，7： | 1 |
| 4 | Prospective evaluation of deep topical fornix nerve block versus peribulbar nerve block in patients undergoing cataract surgery using phacoemulsification 显示文摘 | Aziz E S Samra A | 2000 | Br J Anaesth2000，85，2： | 1 |
| 5 | The effect of selenium deficiency in goats on lymphocyte production of leukocyte migration inhibitory factor 显示文摘 | Aziz E S | 1985 | Vet Immune and Immune Pathology1985，，10： | 1 |
| 6 | Carbon paste electrode bulk-modified with the conducting polymer poly(1,8-diaminonaphthalene):Application to lead determination显示文摘 | Sanaa M Mamia E R Aziz A | 2003 | Mocrochimica Acta2003，143，2： | 1 |
| 7 | Dietary Starch Type Affects Body Weight and Glycemic Control in Freely Fed but Not Energy-Restricted Obese Rats显示文摘 | Aziz A A Kenney L S Goulet B Abdel-Aal E S | 2009 | Journal of Nutrition2009，139，10： | 1 |
| 8 | Optimizing the Performance of a Plug Flow System显示文摘 | Aziz Z B Klinzing G E | 1990 | Powder Technology1990，62，1： | 1 |
| 9 | Calculation ofZ for sour gases显示文摘 | Wichert E Aziz K | 1972 | Hydrocarbon Processing1972，51，5： | 1 |
| 10 | MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages显示文摘 | Aziz A Soucie E Sarrazin S | 2009 | Science2009，326，： | 1 |
| 11 | Influence of some antibiotics used as growth promoters on immune responseof chickens显示文摘 | Abd E T Aziz M T Agag A E | 1996 | Veterinary Medical Journal1996，35，： | 1 |
| 12 | Plug flow transport of cohesive coal:Horizontal and inclined flows 显示文摘 | Aziz Z B Klinzing G E | 1988 | Powder Technology1988，55，2： | 1 |
| 13 | The role of reexcision for positive margins in optimizing local disease control after breast-conserving surgery for cancer显示文摘 | Aziz D Rawlinson E Narod SA | 2006 | Breast J2006，12，4： | 1 |
| 14 | Dense Phase Plug Flow Transfer: the 1-inch Horizontal Flow显示文摘 | Aziz Z B Klinzing G E | 1990 | Powder Technol1990，61，2： | 1 |
| 15 | Some new results on the class of AM - compact operators显示文摘 | BELMESNAOUI A AZIZ E | 2010 | Rendiconti del Cireolo Matematico di Palermo2010，59，： | 1 |
| 16 | Formation of bands of ultrafine beryllium particles during rapid solidification of AL-Be alloys: Modeling and direct observations显示文摘 | Elmer J W Aziz M J Tanner L E | 1994 | Acta Metall Mater1994，42，4： | 1 |
| 17 | Development and evaluation of sustained oral ketorolac tromethamine particulate matrix via bioadhesive chitosan based freeze-dried solid dispersions显示文摘 | Rasool BK Aziz US Abu-Gharbieh E | 2016 | Curt Drug Deliv2016，13，2： | 1 |
| 18 | Dense phase plug flow transfer:The 1 - inch horizontal flow显示文摘 | Aziz Z B Klinzing G E | 1990 | Powder Technol1990，61，2： | 1 |
| 19 | Fatigue and proinflammatory cytokine activity in breast cancer survivors 显示文摘 | Bower J E Ganz P A Aziz N | 2002 | Psychosom Med2002，64，4： | 1 |
| 20 | Long-term neurode- velopmental outcome after fetal arrhythmia显示文摘 | Lopriore E Aziz MI Nagel HT | 2009 | Am J Ob- stet Gynecol2009，201，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员