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| 1 | Advances in nutritional therapy in inflammatory boweldiseases:Review显示文摘Inflammatory bowel diseases(IBD), including ulcerative colitis and Crohn's disease are chronic, life-long, and relapsing diseases of the gastrointestinal tract. Currently, there are no complete cure possibilities, but combined pharmacological and nutritional therapy may induce remission of the disease. Malnutrition and specific nutritional deficiencies are frequent among IBD patients, so the majority of them need nutritional treatment, which not only improves the state of nutrition of the patients but has strong anti-inflammatory activity as well. Moreover, some nutrients, from early stages of life are suspected as triggering factors in the etiopathogenesis of IBD. Both parenteral and enteral nutrition is used in IBD therapy, but their practical utility in different populations and in different countries is not clearly established, and there are sometimes conflicting theories concerning the role of nutrition in IBD. This review presents the actual data from research studies on the influence of nutrition on the etiopathogenesis of IBD and the latest findings regarding its mechanisms of action. The use of both parenteral and enteral nutrition as therapeutic methods in induction and maintenance therapy in IBD treatment is also extensively discussed. Comparison of the latest research data, scientific theories concerning the role of nutrition in IBD, and different opinions about them are also presented and discussed. Additionally, some potential future perspectives for nutritional therapy are highlighted. | Andrzej Wędrychowicz Andrzej Zając Przemysław Tomasik | 2016 | World Journal of Gastroenterology2016，22，3： | 21 |
| 2 | Impact of diet on long-term decline in gastric cancer incidence in Poland显示文摘AIM:To examine the relationship between the trends in food consumption and gastric cancer morbidity in Poland.METHODS:The study was based on gastric cancer incidence rates and consumption of vegetables,fruit,vitamin C and salt in Poland between 1960 and 2006.Food consumption data were derived from the national food balance sheets or household budget surveys.Spearman correlation coefficients were used to estimate the relationship between the variables.RESULTS:A negative correlation was found between vegetables(-0.70 both for men and women;P < 0.0001),fruit(-0.65 and-0.66;P < 0.0001) and vitamin C(-0.75 and-0.74;P < 0.0001) consumption and stomach cancer incidence rates.The same applied to the availability of refrigerators in the household(-0.77 and-0.80;P < 0.0001).A decline in these rates could also be linked to reduction in salt intake.CONCLUSION:The decline of gastric cancer incidence probably resulted from increased consumption of vegetables,fruit and vitamin C and a decrease in salt consumption. | Mirosaw Jarosz Wodzimierz Sekua Ewa Rychlik Katarzyna Figurska | 2011 | World Journal of Gastroenterology2011，17，1： | 7 |
| 3 | Ghrelin and gastrin in advanced gastric cancer before and after gastrectomy显示文摘AIM: To investigate plasma ghrelin, gastrin and growth hormone secretagogue receptor (GHS-R) expression in advanced gastric cancer (GC) before and after resection. METHODS: Seventy subjects in whom endoscopy of the upper gastrointestinal tract was performed in the Department of General Surgery at Cracow University during the past decade: (1) 25 patients with GC associated with Helicobacter pylori (H. pylori) infection; (2) 10 patients with GC 4-5 years after (total or subtotal) gastrectomy; (3) 25 healthy H. pylori-negative controls, matched by age and BMI to the above two groups; and (4) 10 GC patients 4-5 years after total gastrectomy. Ghrelin and gastrin plasma concentrations were measured by specific radioimmunoassay under fasting conditions and postprandially at 60 and 90 min after ingestion of a mixed meal. GHS-R expression was examined in biopsy samples from intact healthy mucosa and GC tissue using semi-quantitative reverse transcription-polymerase chain reaction. RESULTS: In healthy controls, fasting plasma ghrelin levels were significantly elevated and declined markedly at 60 and 90 min after a mixed meal. The concomitant enhanced ghrelin, GHS-R and gastrin expression in GC tissue over that recorded in intact mucosa, and the marked rise in plasma gastrin in these subjects under fasting conditions indicate the role of these hormonal factors in GC formation. Fasting plasma levels and postprandial response of ghrelin and gastrin appear to be inversely correlated in healthy subjects. Feeding in the controls resulted in a significant fall in plasma ghrelin with a subsequent rise in plasma gastrin, but in H. pylori-positive GC patients submitted to total or distal gastrectomy, feeding failed to affect significantly the fall in plasma ghrelin that was recorded in these patients before surgery. Fasting ghrelin concentrations were significantly lower in patients 4-5 years after total gastrectomy compared to those in healthy controls and to these in GC patients before surgery. CONCLUSION: Elevated plasma gastrin and suppression of fasting ghrelin in patients with GC suggest the existence of a close relationship between these two hormones in gastric carcinogenesis. | Anna Zub-Pokrowiecka Kazimierz Rembiasz Peter C Konturek Andrzej Budzyński Stanisaw J Konturek Marek Winiarski Wadysaw Bielański | 2011 | World Journal of Gastroenterology2011，17，4： | 7 |
| 4 | 脊髓损伤后残存自主神经功能载录国际标准显示文摘近年来,脊髓损伤神经学分类园际标准(International Stand- ards for the Neurological Classification of Spinal Cord Injury, ISNCSCI)被用来记载脊髓损伤后运动和感觉功能的损害,目前该标准已是第六版。1992年第一份国际认可的标准出版时,曾进行了较大的修订,修订内容包括完全性损伤与不完全性损伤的定义, | MS Alexander AB Jackson W Donovan DE Graves SL Elliott A Krassioukov AW Sheel I Estoresl B Green A Gousse NL Braekett D Cardenas M Kennelly A-K Karlason F Biering-Sorensen K Krogh T Linsenmeyer R Marino J Ditunno CJ Mathias I Perkash G Creasey G Schilero J Wecht B Schurch V Dietz J Sonksen S Stiens D Bodner LA Wuermser J-J Wyndaele 周谋望 刘楠 S Charlifue | 2010 | 中华物理医学与康复杂志2010，32，4： | 2 |
| 5 | Korean pine nut fatty acids affect appetite sensations,plasma CCK and GLP 1 in overweight subjects 显示文摘 | Einerhand AW Pasman W Rubingh C | 2006 | FASEB J2006，20，： | 1 |
| 6 | Age-dependent changes in heparan sulfate in human Bruch' s membrane: implications for age- related macular degeneration 显示文摘 | KEENAN TD PICKFORD CE HOLLEY R J CLARK S J LIN W DOWSEY AW | 2014 | Invest Ophthalmol Vis Sci2014，55，8： | 1 |
| 7 | Retrospective analysis of 5037patients with nasopharyngeal carcinoma treated during 19761985:overall survival and patterns of failure显示文摘 | Lee AW Poon YF Foo W | 1992 | lnt J Radiat Oncol Biol Phys1992，23，2： | 1 |
| 8 | Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976~1985:overall survival and patterns of failure显示文摘 | Lee AW Poon YF W | 1992 | Int J Radiat Oncol Biol Phys1992，23，： | 1 |
| 9 | Retrospective and analysis of 5037 patients with nasopharyngeaI carcinoma treated during 1976 - 1985 :overall survival and patterns of failure 显示文摘 | Lee AW Poon YF Foo W | 1992 | Int J Radiat OncoI Biol Phys1992，23，2： | 1 |
| 10 | Limiting dynamics of high-frequency electromechanical transduction of outer hair cells显示文摘 | Frank G Hemmert W Gummer AW | 1999 | Proc Natl Acad Sci USA1999，96，： | 1 |
| 11 | Effect of time,dose and fractionation on temporal lobe necrosis following radiotherapy for nasopharyngeal carcinoma显示文摘 | Lee AW Foo W Chappell R | 1998 | Int J Radiat Oncol Biol Phys1998，40，1： | 1 |
| 12 | Inhibition of pre-B cell colony- enhancing factor attenuates inflammation and apoptosis induced by pandemic HIN1 2009 in lung endothelium显示文摘 | Gao W Mao Oa Feng AW | 2011 | Respir Physiol Neurobiol2011，178，2： | 1 |
| 13 | Staging of nasopharyngeal carcinoma: From Ho's to the new UICC system显示文摘 | Lee AW Foo W Lo SC | 1999 | Int J Cancer1999，84，2： | 1 |
| 14 | Teaching and testing physical examination skills without the use of patients显示文摘 | Karnath B Thornton W Frye AW | | 0，，07： | 1 |
| 15 | Carcinogenicity of benzol a] pyrene and thirteen of its derivatives in C3HPf Cure mice显示文摘 | Kourir E Wood AW Levin W | 1980 | J Natl Cancer Inst1980，64，3： | 1 |
| 16 | Caveolin-l(-/-)- and caveolin-2 (-/-)-deficient mice both display numerous skeletal muscle abnormalities, with tubular aggregate formation 显示文摘 | Schubert W Sotgia F Cohen AW | 2007 | Am J Pathol2007，，170： | 1 |
| 17 | Stathminl plays onco-genic role and is a target of microRNA-223 in gastric can-cer显示文摘 | Kang W Tong JH Chan AW | 2012 | PLoS One2012，7，33： | 1 |
| 18 | Retres pective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976 - 1985 : overall Survival and Patterns of failure显示文摘 | Lee AW Poon YF Foo W | 1992 | Int J Radiat Oncol Biol Phys1992，23，： | 1 |
| 19 | Effect of time, dose, and fractionatlon on temporal lobe necrosis following radiotherapy for nasopharyngeal carcinoma 显示文摘 | Lee AW Foo W Chappell R | 1998 | Int J Radiat Oncol Biol Phys1998，40，1： | 1 |
| 20 | Transcriptional profiling in rats and an ex vivo analysis implicate novel beneficial function of egg shell membrane in liver fibrosis显示文摘 | Jia H Saito K Aw W | 2013 | J Funct Foods2013，5，4： | 1 |
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