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	题名	作者	年代	出处	被引量
1	Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension显示文摘AIM:Adrenomedullin (ADM) is a potent vasodilator peptide.ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown, plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.METHODS: There were 4 groups of subjects. Group 1consisted of 27 patients (F/M: 12/15) with NCPH due to portal and/or splenic vein thrombosis (mean age: 41±12years), group 2 consisted of 14 patients (F/M: 6/8) with compensated (Child-Pugh A) cirrhosis (mean age: 46±4),group 3 consisted of 16 patients (F/M: 6/10) with decompensated (Child-Pugh C) cirrhosis (mean age: 47±12).Fourteen healthy subjects (F/M: 6/8) (mean age: 44±8) were used as controls in Group 4. ADM level was measured by ELISA. NO was determined as nitrite/nitrate level by chemoluminescence.RESULTS: Adl level in Group 11 (236±61.4 pg/mL) was significantly higher than that in group 2 (108.4±28.3 pg/mL)and group 4 (84.1±31.5 pg/mL) (both P<0.0001) but was lower than that in Group3 (324±93.7 pg/mL) (P=0.002). NO level in group 1 (27±1.4 μmol/L) was significantly higher than that in group 2 (19.8±2.8 μmol/L) and group 4 (16.9±1.6μmol/L) but was lower than that in Group 3 (39±3.6 μmol/L)(for all three P<0.0001). A strong correlation was observed between ADM and NO levels (r=0.827, P<0.0001).CONCLUSION: Adrenomedullin and NO levels were high in both non-cirrhotic and cirrhotic portal hypertension and were closely correlated, Adrenomedullin and NO levels increased proportionally with the severity of cirrhosis, and were significantly higher than those in patients with NCPH.Portal hypertension plays an important role in the increase of ADM and NO. Parenchymal damage in cirrhosis may contribute to the increase in these parameters.	V Tahan E Avsar C Karaca E Uslu F Eren S Aydin H Uzun HO Hamzaoglu F Besisik C Kalayci A Okten N Tozun	2003	World Journal of Gastroenterology2003，9，10：	5
2	Diphenhydramine and hyaluronic acid derivatives reduce adnexal adhesions and prevent tubal obstructions显示文摘	Avsar AF Avsar F Sahin M	2003	Eur J Obstet Gynecol Reprod Biol2003，106，1：	1
3	Induction and assessment methods used in experimental adhesion studies显示文摘	OZEL H AVSAR F M TOPALOGLU S	2005	Wound Repair Regen2005，13，4：	1
4	Maternal serum levels of dehydroepiandrosterone sulfate and labor induction in postterm pregnancies显示文摘	Doganay M Erdemoglu E Avsar A F	2004	Int J Gynaecol Obstet2004，85，3：	1
5	The effects of anti-adhesion materials in preventing postoperative adhesion in abdominal cavity( antiadhesion materials for postoperative adhesions) 显示文摘	Sahin M Cakir M Avsar F M	2007	Inflammation2007，30，6：	1
6	Correlation of risk and postoperative assessment methods in wound surveillance显示文摘	Topaloglu S Akin M Avsar F M	2008	J Surg Res2008，146，2：	1
7	A girl with constipation and acute urinary retention显示文摘	Kitapci F Avsar AG Senses DA	1999	Eur J Pediatr1999，158，4：	1
8	Rosiglitazone attenuates liver inflammation in a rat model of nonalcoholic steatohepatitis 显示文摘	Tahan V Eren F Avsar E	2007	Dig Dis Sci2007，52，：	1
9	Benign cystic lymphangioma presenting as a pelvic mass显示文摘	Erdem S Isk Ender C Avsar A F	2006	J Obstet Gynaecol Res2006，32，：	1
10	Rosiglitazone attenuates liver inflam- mation in a rat model of nonalcoholic steatohePatitis显示文摘	Tahan V Eren F Avsar E	2007	Digestive Dis- eases and Sciences2007，52，12：	1
11	The e- valuation of oxidative stress in the serum and tissue specimens of patients with chronic otitis media显示文摘	GARA M F TURAN M AVSAR B	2015	Clin Exp Otorhinolaryngol2015，8，：	1
12	Risk factors for ectopic pregnancy : A case-control study 显示文摘	Karaer A Avsar F A Btioglu S	2006	Australian and New Zealand Journal of Obstetrics and Gynaecology2006，11，46：	1
13	Risk factors for ectopic pregnancy:a case-control stlldy显示文摘	Karaer A AVsar F Batioglu S	2006	Amst N Z J Obstet Gynaec012006，46，6：	1
14	Vaginitis in turkish women: Symptoms, epidemiologic-microbiologic association Euro显示文摘	Karaer A Boylu M Avsar A F	2005	Obstet Gynecol Reprod Biol2005，121，：	1
15	Risk factors for ectopic pregnancy: a ease-control study显示文摘	Karaer A Avsar F A Batioglu S	2006	Aust N Z J Obstet Gynaecol2006，46，6：	1
16	Rosiglitazone attenuates liver inflammation in a rat model of nonalcoholic steatohepatitis 显示文摘	Tahan V Eren F Avsar E	2007	Dig Dis Sci2007，52，12：	1
17	Induction and assessment methods used in experimental adhesion studies显示文摘	Ozel H Avsar F M Topaloglu S	2005	Wound Repair Regen2005，13，4：	1
18	Unexpected fetal demise despite the reactive nonstress test during the conservatiVe management of acute pancreatitis in pregnancy 显示文摘	Avsar A F Yildirim M Cinkaya A	2014	Int J Surg Case Rep2014，5，12：	1
19	Benign cystic lym- phangioma presenting as a pelvic mass显示文摘	Erdem S Iskender C Avsar A F	2006	J Obstet Gynaecol Res2006，32，6：	1
20	Diphenhydramine and hyaluronic acid derivatives reduce adnexal adhesions and prevent tubal obstructions显示文摘	Avsar AF Avsar F Sahin M	2003	Eur J 0bstet Gynecoi Reprod Biol2003，106，1：	1

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