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72篇 您的检索式：作者名="Auste B"

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	题名	作者	年代	出处	被引量
1	Predictive value of Ki67 and p53 in locally advanced rectal cancer:Correlation with thymidylate synthase and histopathological tumor regression after neoadjuvant 5-FU-based chemoradiotherapy显示文摘AIM: To investigate the predictive value of Ki67 and p53 and their correlation with thymidylate synthase (TS) gene expression in a rectal cancer patient cohort treated according to a standardized recommended neoadjuvant treatment regimen.METHODS: Formalin fixed, paraffin embedded pre-therapeutical tumor biopsies (n = 22) and post-therapeutical resection specimens (n = 40) from patients with rectal adenocarcinoma (clinical UICC stage Ⅱ/Ⅲ) receiving standardized neoadjuvant 5-fluorouracil (5-FU) based chemoradiotherapy were studied for Ki67 and p53 expression by immunohistochemistry and correlated with TS mRNA expression by quantitative TaqMan real-time PCR after laser microdissection. The results were compared with histopathological tumor regression according to a standardized semiquantitative score grading system.RESULTS: Responders (patients with high tumor regression) showed a significantly lower Ki67 expression than non-responders in the pre-therapeutical tumor biopsies (81.2% vs 16.7%; P < 0.05) as well as in the post-therapeutical resection specimens (75.8% vs 14.3%; P < 0.01). High TS mRNA expression was significantly correlated with a high Ki67 index and low TS mRNA expression was significantly correlated with a low Ki67 index in the pre-therapeutical tumor biopsies (corr. coef. = 0.46; P < 0.01) as well as in the post-therapeutical resection specimens (corr. coef. = 0.40; P < 0.05). No significant association was found between p53 and TS mRNA expression or tumor regression.CONCLUSION: Ki67 has, like TS, predictive value in rectal cancer patients after neoadjuvant 5-FU based chemoradiotherapy. The close correlation between Ki67 and TS indicates that TS is involved in active cell cycle processes.	Christiane Jakob Torsten Liersch Wolfdietrich Meyer Heinz Becker Gustavo B Baretton Daniela E Aust	2008	World Journal of Gastroenterology2008，14，7：	29
2	Yield of human adipose-derived adult stem cells from liposuction aspirates显示文摘	Aust L Devlin B Foster SJ	2004	Cytotherapy2004，6，1：	1
3	Corrosion and auger studies of a nickel-base matalmetalloid glass: ( 显示文摘	THORPE S J RAMASWAMNI B AUST E T	1988	J Electro Chem Soc1988，135，9：	1
4	The Impact of Operative Complexity on Patient Risk Factors显示文摘	Aust J B Henderson W Khuri S	2005	Ann Surg2005，241，6：	1
5	Yield of human adipose-derived adult stem cells from liposuction aspirates显示文摘	Aust L Devlin B Foster SJ	2004	Cytotherapy2004，6，1：	1
6	Yield of human adipose-derived adult stem cells from liposuction aspirates显示文摘	Aust L Devlin B Foster SJ		0，，01：	1
7	Yield of human adipose derived adult stem cells from liposuction aspirates显示文摘	Aust L Devlin B Foster SJ	2004	Cytotherapy2004，6，1：	1
8	Biomass and carbon pools of disturbed riparian forests显示文摘	LAURA A B G AUST W M RANDALL K K	2003	Forest Ecology and Management2003，180，：	1
9	Serrated polyps of the colon and rectum (hyperplastic polyps, sessile serrated adenomas, traditional serrated adenomas, and mixed polyps)-proposal for diagnostic criteria 显示文摘	Aust D E Baretton G B	2010	Virchows Arch2010，457，3：	1
10	Biologically aclive secondary rnetabolites of endophytic Pezicula species显示文摘	SchuIz B Sucker J Aust H J	1995	MycolRes1995，99，10：	1
11	Corrosion and Auger studies of a nickel-base metal-metalloid glass 显示文摘	Thorpe S J Ramaswami B Aust K T	1988	Journal of Electrochemical Society1988，135，：	1
12	Yield of human adipose-derived adult stem cells from liposuction aspirates 显示文摘	Aust L Devlin B Foster S	2004	Cyto2therapy2004，6，1：	1
13	Yield of adult human adipose-derived stem cells from liposuction aspirates显示文摘	DEVLIN B FOSTER S	2004	Cytotherapy2004，6，1：	1
14	Yield of human adipose-derived adult stem cells from liposuction aspirates显示文摘	Aust L Devlin B Foster SJ		Cytotherapy0，6，1：	1
15	Yield of human adipose derived adult stem ceils from liposuction aspirates显示文摘	Aust L Devlin B Foster SJ	2004	Cytotherapy2004，6，1：	1
16	Yield of human adipose-derived adult stem cells from liposuction aspirates显示文摘	Aust L Devlin B Foster S J	2007	Cytotherapy2007，，6：	1
17	Yield of human adipose-derived adult stem cells from liposuction aspirates显示文摘	Aust L Devlin B Foster SJ	2004	Cytotherapy2004，6，1：	1
18	Hantavirus in bat,Sierra Leone显示文摘	Weiss S Witkowski P T Auste B	2012	Emerg Infect Dis2012，18，1：	1
19	Yield of human adipose-derived adult stem cells from liposuction aspirates显示文摘	AUST L DEVLIN B FOSTER S J	2004	Cytotherapy2004，6，1：	1
20	An investigation into the role of hydroxyl radical in xanthine oxidase-dependent lipid peroxidation 显示文摘	Tien M Svingen B A Aust S D	1982	Archives of Biochemistry and Biophysics1982，216，1：	1

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