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| 1 | FDG-PET/CT response evaluation during EGFR-TKI treatment in patients with NSCLC显示文摘Over recent years,[18F]-fluorodeoxyglucose positron emission tomography acquired together with low dose computed tomography(FDG-PET/CT)has proven its role as a staging modality in patients with non-small cell lung cancer(NSCLC).The purpose of this review was to present the evidence to use FDG-PET/CT for response evaluation in patients with NSCLC,treated with epidermal growth factor receptor(EGFR)-tyrosine kinase inhibitors(TKI).All published articles from 1November 2003 to 1 November 2013 reporting on 18FFDG-PET response evaluation during EGFR-TKI treatment in patients with NSCLC were collected.In total 7studies,including data of 210 patients were eligible for analyses.Our report shows that FDG-PET/CT responseduring EGFR-TKI therapy has potential in targeted treatment for NSCLC.FDG-PET/CT response is associated with clinical and radiologic response and with survival.Furthermore FDG-PET/CT response monitoring can be performed as early as 1-2 wk after initiation of EGFR-TKI treatment.Patients with substantial decrease of metabolic activity during EGFR-TKI treatment will probably benefit from continued treatment.If metabolic response does not occur within the first weeks of EGFR-TKI treatment,patients may be spared(further)unnecessary toxicity of ineffective treatment.Refining FDG-PET response criteria may help the clinician to decide on continuation or discontinuation of targeted treatment. | Matthijs H van Gool Tjeerd S Aukema Koen J Hartemink Renato A Valdés Olmos Houke M Klomp Harm van Tinteren | 2014 | World Journal of Radiology2014，6，7： | 8 |
| 2 | Initial assessment of chest X-ray in thoracic trauma patients: Awareness of specific injuries显示文摘AIM: To compare the reported injuries on initial assessment of the chest X-ray (CXR) in thoracic trauma patients to a second read performed by a dedicated trauma radiologist. METHODS: By retrospective analysis of a prospective database, 712 patients with an injury to the chest admitted to the University Medical Center Utrecht were studied. All patients with a CXR were included in the study. Every CXR was re-evaluated by a trauma radiologist, who was blinded for the initial results. The findings of the trauma radiologist regarding rib fractures, pneumothoraces, hemothoraces and lung contusions were compared with the initial reports from the trauma team, derived from the original patient files. RESULTS: A total of 516 patients with both thorax trauma and an initial CXR were included in the study. After re-evaluation of the initial CXR significantly more lung contusions (53.3% vs 34.1%, P < 0.001), hemothoraces (17.8% vs 11.0%, P < 0.001) and pneumothoraces (34.4% vs 26.4%, P < 0.001) were detected.During initial assessment significantly more rib fractures were reported (69.8% vs 62.3%, P < 0.001). CONCLUSION: During the initial assessment of a CXR from trauma patients in the emergency department, a significant number of treatment-dictating injuries are missed. More awareness for these specific injuries is needed. | Tjeerd S Aukema Ludo FM Beenen Falco Hietbrink Luke PH Leenen | 2012 | World Journal of Radiology2012，4，2： | 3 |
| 3 | Modeling flight activity and population dynamics of the pine engraver, Ips pini, in the Great Lakes region: effects of weather and predators over short time scales显示文摘 | Aukema B H Clayton M K Raffa K F | 2005 | Population Ecology2005，47，1： | 1 |
| 4 | A comparison of tools for modeling freshwater ecosystem services显示文摘 | Vigerstol K L Aukema J E | 2011 | Journal of Environmental Management2011，92，10： | 1 |
| 5 | Double-hit B-cell lympho- mas显示文摘 | Aukema SM Siebert R Schuuring E | 2011 | Blood2011，117，8： | 1 |
| 6 | Selective COX-2 inhibition markedly slows disease progression and attenuates altered prostanoid production in Han: SPRD-cy rats with inherited kidney disease显示文摘 | Sankaran D Bankovic-Calic N Ogborn M R Crow G Aukema H M | 2007 | Am J Physiol Renal Physiol2007，293，： | 1 |
| 7 | Double-hit B-cell lymphomas显示文摘 | Aukema SM Siebert R Schuuring E | 2011 | Blood2011，117，8： | 1 |
| 8 | Flaxseed consumption reduces blood pressure in patients with hypertension by altering circulating oxylipins via an alpha - linalenic acid - induced inhibition of soluble epoxide hydrolase 显示文摘 | Caligiuri SP Aukema HM Ravandi A | 2014 | Hypertension2014，64，1： | 1 |
| 9 | Predicting early chemotherapy response with technetium-99m methoxyisobutylisonitrile SPECT/CT in advanced non-small cell lung cancer显示文摘 | Yang T J Aukema T S van-Tinteren H | 2010 | Mol Imaging Biol2010，12，2： | 1 |
| 10 | Feasibi|ity of FDG PET/CT to monitor the response of axillary lymph node metastases to neoadjuvant chemotherapy in breast cancer patients 显示文摘 | Strayer ME Aukema TS O|mos RA | 2010 | Eur J Nucl Med Mol Imaging2010，37，6： | 1 |
| 11 | Double-hit B-cell lymphomas 显示文摘 | Aukema SM Siebert R Schuuring E | 2011 | Blood2011，117，8： | 1 |
| 12 | Double-hit B-cell lym- phomas显示文摘 | Aukema SM Siebert R Schuuring E | 2011 | Blood2011，117，8： | 1 |
| 13 | Can previous diagnostic examinations prevent preoperative angiographic assessment of the internal mammary perforators for(micro)surgical use显示文摘 | Schellekens PP Aukema TS Hage JJ | 2014 | Ann Plast Surg2014，72，5： | 1 |
| 14 | Double-hit B-cell lym- phomas显示文摘 | Aukema SM Siebert R Schuuring E | 2011 | Blood2011，117，8： | 1 |
| 15 | Treatment of nasal polyposis and chronic rhinosinusitis with fluticasone propionate nasal drops reduces need for sinus surgery显示文摘 | AUKEMA A A MULDER P G FOKKENS W J | 2005 | J Allergy Clin Immunol2005，115，： | 1 |
| 16 | Effects of dietary conjugated Iinoleic acid in advanced experimental polycystic kidney disease显示文摘 | Scatliff C E Bankovic-Calic N Ogborn M R Aukema H M | 2008 | Nephron Exp Nephrol 20082008，4448，： | 1 |
| 17 | Variation in mistletoe seed deposition: effects of intra- and interspecific host characteristics 显示文摘 | Aukema J Martinez del Rio C 2002 | 2002 | Ecography2002，25，： | 1 |
| 18 | Vectors, viscin, and Viscaeae: Mistletoes as parasites, mutualists, and resources 显示文摘 | Aukema J 2003 | 2003 | Frontiers in Ecology and the Environment2003，1，： | 1 |
| 19 | Treatment of nasal polyposis and chronic rhinosinusitis with fluticasone propionate nasal drops reduces need for sinus surgery显示文摘 | Aukema AAC Mulder PGH Fokkens WJ | 2005 | J Allergy Clin Immunol2005，115，5： | 1 |
| 20 | Distribution and dispersal of desert mis- tletoe is scale - dependent, hierarchically nested 显示文摘 | AUKEMA J E | 2004 | Ecography2004，27，2： | 1 |
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