|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Metabolic syndrome and colorectal neoplasms:An ominous association显示文摘AIM:To evaluate the association of metabolic syndrome(MS) and colorectal cancer and adenomas in a Western country,where the incidence of MS is over 27%.METHODS:This was a prospective study between March 2013 and March 2014.MS was diagnosed according to the National Cholesterol Education ProgramATP III.Demographic characteristics,anthropometric measurements,metabolic risk factors,and colonoscopic pathologic findings were assessed in patients with MS(group 1) who underwent routine colonoscopy at our department.This data was compared with consecutive patients without metabolic syndrome(group 2),with no differences regarding sex and age.Patients with incomplete colonoscopy,family history,or past history of colorectal neoplasm were excluded.Informed consent was obtained and the ethics committee approved this study.Statistical analysis was performed using Student's t-test and χ2 test,with a P value ≤ 0.05 being considered statistically significant.RESULTS:Of 258 patients,129 had MS;51% males;mean-age 67.1 years(50-87).Among the MS group,94% had high blood pressure,91% had increased waist circumference,60% had diabetes,55% had low high-density lipoprotein cholesterol level,50% had increased triglyceride level,and 54% were obese [body mass index(BMI) 30 kg/m2].51% presented 4 criteria of MS.MS was associated with increased prevalence of adenomas(43% vs 25%,P = 0.004) and colorectal cancer(13% vs 5%,P = 0.027),compared with patients without MS.MS was also positively associated with multiple(≥ 3) adenomas(35% vs 9%,P = 0.024) and sessile adenomas(69% vs 53%,P = 0.05).No difference existed between location(P = 0.086),grade of dysplasia(P = 0.196),or size(P= 0.841) of adenomas.In addition,no difference was found between BMI(P = 0.078),smoking(P = 0.146),alcohol consumption(P = 0.231),and the presence of adenomas.CONCLUSION:MS is positively associated with adenomas and colorectal cancer.However,there is not enough information in western European countries to justify screening in patients with MS.To our knowledge,no previous study has evaluated this association in Portuguese patients. | Daniel Trabulo Suzane Ribeiro Cláudio Martins Cristina Teixeira Cláudia Cardoso Jo?o Mangualde Ricardo Freire élia Gamito Ana L Alves Fátima Augusto Ana P Oliveira Isabelle Cremers | 2015 | World Journal of Gastroenterology2015，21，17： | 5 |
| 2 | Current aspects of renal dysfunction after liver transplantation显示文摘The development of chronic kidney disease(CKD)after liver transplantation(LT)exerts a severe effect on the survival of patients.The widespread adoption of the model for end-stage liver disease score strongly impacted CKD incidence after the procedure,as several patients are transplanted with previously deteriorated renal function.Due to its multifactorial nature,encompassing pre-transplantation conditions,perioperative events,and nephrotoxic immunosuppressor therapies,the accurate identification of patients under risk of renal disease,and the implementation of preventive approaches,are extremely important.Methods for the evaluation of renal function in this setting range from formulas that estimate the glomerular filtration rate,to non-invasive markers,although no option has yet proved efficient in early detection of kidney injury.Considering the nephrotoxicity of calcineurin inhibitors(CNI)as a factor of utmost importance after LT,early nephroprotective strategies are highly recommended.They are based mainly on delaying the application of CNI during the immediate postoperativeperiod,reducing their dosage,and associating them with other less nephrotoxic drugs,such as mycophenolate mofetil and everolimus.This review provides a critical assessment of the causes of renal dysfunction after LT,the methods of its evaluation,and the interventions aimed at preserving renal function early and belatedly after LT. | Mariana P Pacheco Luiz Augusto Carneiro-D'Albuquerque Daniel F Mazo | 2022 | World Journal of Hepatology2022，14，1： | 5 |
| 3 | Appropriateness of outpatient gastrointestinal endoscopy in a non-academic hospital显示文摘AIM:To assess the appropriate use and the diagnostic yield of upper gastrointestinal endoscopy and colonoscopy in this subgroup of patients.METHODS:In total,789 consecutive outpatients referred for gastrointestinal(GI) endoscopy [381 for esophagogastroduodenoscopy(EGD) and 408 for colonoscopy] were prospectively enrolled in the study.The American Society for Gastrointestinal Endoscopy(ASGE) guidelines were used to assess the relationship between appropriateness and the presence of relevant endoscopic f indings.RESULTS:The overall inappropriate rate was 13.3%.The indications for EGD and colonoscopy were,respectively,appropriate in 82.7% and 82.6% of the exams,uncertain in 5.8% and 2.4% and inappropriate in 11.5% and 15%.The diagnostic yield was signif icant higher forEGDs and colonoscopies judged appropriate and uncertain when compared with those considered inappropriate(EGD:36.6% vs 36.4% vs 11.4%,P = 0.004;Colonoscopy:24.3% vs 20.0% vs 3.3%,P = 0.001).Of the 25 malignant lesions detected,all but one was detected in exams judged appropriate or uncertain.CONCLUSION:This study shows a good adherence to ASGE guidelines by the referring physicians and a significant increase of the diagnostic yield in appropriate examinations,namely in detecting neoplastic lesions.It underscores the importance that the appropriateness of the indication assumes in assuring high-quality GI endoscopic procedures. | Joo Mangualde Marie I Cremers Ana M Vieira Ricardo Freire lia Gamito Cristina Lobato Ana L Alves Fátima Augusto Ana P Oliveira | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，10： | 2 |
| 4 | Optimization of refrigerated shields using multilayer thermal insulation Cryostats designanalytical solution 显示文摘 | Augusto P A Grande T C Augusto P | 2006 | Cryogenics2006，46，： | 1 |
| 5 | Impact of tree spe cies on forestsoil acidification显示文摘 | Augusto L Bonnaud P Ranger J | 1998 | Forest Ecology and Management1998，105，13： | 1 |
| 6 | A modified direct power control strategy allowing the connection of three-phase inverters to the grid through LCL filters显示文摘 | Augusto Serpa L Ponnaluri S Mantovanelli Barbosa P | 2007 | IEEE Transactions on Industrial Applications2007，43，5： | 1 |
| 7 | Pressures on open canopy structures with parapets under wind loading显示文摘 | Augusto P Bruno N Luis A G | 2013 | EngineeringStructures2013，56，6： | 1 |
| 8 | Inactivation of formyltransferase(wbk C)gene generates a Brucella abortus rough strain that is attenuated in macrophages and in mice显示文摘 | LACERDA T L CARDOSO P G AUGUSTO D E ALMEIDA L | 2010 | Vaccine2010，28，： | 1 |
| 9 | Numerical simulation of packed liquid food thermal process using computational fluid dynamics (CFD) 显示文摘 | Augusto P E D Cristianini M | 2011 | International Journal of Food Engineering2011，7，4： | 1 |
| 10 | Perineural invasion in adenoid cystic carcinoma: Its causation/promotion by brain-derived neurotrophic factor显示文摘 | Paul J Kowalski P Augusto F | 2002 | Hum Pathol2002，33，9： | 1 |
| 11 | Perineural invasion in adenoid cystic carcinoma: Its causation/promotion by brain-derived neurotrophic factor显示文摘 | Kowalski P Augusto F | 2002 | Hum Pathol2002，33，9： | 1 |
| 12 | Numerical simulation of packed liquid food thermal process using computational flu- id dynamics 显示文摘 | Augusto P E D Cristianini M | 2011 | International Journal of Food Engineer- ing2011，7，4： | 1 |
| 13 | Evaluation of geometric symmetry condition in numerical simulations of thermal process of packed liquid food by computational fluid dy- namics (CFD) 显示文摘 | Augusto P E D Cristianini M | 2010 | International Journal of Food Engi- neering2010，6，5： | 1 |
| 14 | Attention and executive function sprofile in drug naive ADHD subtypes显示文摘 | Augusto P Claudio P Riccardo A | | 0，，07： | 1 |
| 15 | Computational fluid dynam- ics analysis of viscosity influence on thermal in-package liquid food process 显示文摘 | Augusto P E D Cristianini M | 2010 | International Journal of Food En- gineering2010，6，6： | 1 |
| 16 | Numerical simulation of packed liquid food thermal process using computational fluid dynamics(CFD)显示文摘 | Augusto P E D Cristianini M | 2011 | International Journal of Food Engineering2011，7，4： | 1 |
| 17 | Efficacy and safety of adjunctive mitomycin C during Ahmed Glaucoma Valve implantation显示文摘 | Vital P Costa Augusto Azuara-Blanco Peter A Netland Mark R Lesk Enyr S Arcieri | 2004 | Ophthalmology2004，，6： | 1 |
| 18 | Determining the Convective Heat Transfer Coefficient (h) in Thermal Process of Foods显示文摘 | Augusto P E D Cristianini M | 2011 | International Journal of Food Engineering2011，7，4： | 1 |
| 19 | Magnetic classification显示文摘 | Augusto P A Augesto P Castelo-Grande T | 2002 | Minerals Engineering2002，15，12： | 1 |
| 20 | Septicshock sera containing circulating histones induce dendritic cellregulatednecrosis in fatal septic shock patients显示文摘 | Raffray L Douchet I Augusto JF Youssef J Contin-BordesC Richez C Duffau P Truchetet ME Moreau JF Cazanave C Leroux L Mourrissoux G Camou F Clouzeau B Jeannin P Delneste Y Gabinski C Guisset O Lazaro E Blanco P | 2015 | Crit CareMed2015，43，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员