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		题名	作者	年代	出处	被引量
	1	Antiplasmodial activity of traditional polyherbal remedy from Odisha, India:Their potential for prophylactic use显示文摘Objective:To evaluate the potential prophylactic activity of traditional polyherbal remedy against malaria.Methods:A traditional polyherbal remedy against malaria from Odisha,India was evaluated for its potential prophylactic activity using in vitro hepatic cell lines assay and the murine malaria system Plasmodium yoelii yoelii/Anopheles stephensi.Results:The polyherbal extract inhibited the Plasmodium yoelii hepatic stages in vitro(IC500.74 mg/m L),a therapeutic index of 9.54.In mice treated with the aqueous extract(2 000 mg/kg/day),peak parasitaemia values were 81%lower in the experimental2.35%±0.14%as compared to controls 12.62%±0.52%(P<0.001),suggesting significant prophylactic activity.Conclusions:The observations provide a proof of concept for a traditional malaria prophylactic remedy used by tribal populations in India.	Prakash Bangalore Nagendrappa Jean-Francois Franetich Frederick Gay Audrey Lorthiois Padma Venkatasubramanian Dominique Mazier	2015	Asian Pacific Journal of Tropical Biomedicine2015，5，12：	1

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