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| 1 | Transit time ultrasound perivascular flow probe technology is superior to MR imaging on hepatic blood flow measurement in a porcine model显示文摘Background: The hepatic hemodynamics is an essential parameter in surgical planning as well as in various disease processes. The transit time ultrasound(TTUS) perivascular flow probe technology is widely used in clinical practice to evaluate the hepatic inflow, yet invasive. The phase-contrast-MRI(PC-MRI) is not invasive and potentially applicable in assessing the hepatic blood flow. In the present study, we compared the hepatic inflow rates using the PC-MRI and the TTUS probe, and evaluated their predictive value of post-hepatectomy adverse events. Methods: Eighteen large white pigs were anaesthetized for PC-MRI and approximately 75% hepatic resection was performed under a unified protocol. The blood flow was measured in the hepatic artery(Qha), the portal vein(Qpv), and the aorta above the celiac trunk(Qca) using PC-MRI, and was compared to the TTUS probe. The Bland-Altman method was conducted and a partial least squares regression(PLS) model was implemented. Results: The mean Qpv measured in PC-MRI was 0.55 ± 0.12 L/min, and in the TTUS probe was 0.74 ± 0.17 L/min. Qca was 1.40 ± 0.47 L/min in the PC-MRI and 2.00 ± 0.60 L/min in the TTUS probe. Qha was 0.17 ± 0.10 L/min in the PC-MRI, and 0.13 ± 0.06 L/min in the TTUS probe. The Bland-Altman method revealed that the estimated bias of Qca in the PC-MRI was 32%(95% CI:-49% to 15%); Qha 17%(95% CI:-15% to 51%); and Qpv 40%(95% CI:-62% to 18%). The TTUS probe had a higher weight in predicting adverse outcomes after 75% resection compared to the PC-MRI( β= 0.35 and 0.43 vs β = 0.22 and 0.07, for tissue changes and premature death, respectively). Conclusions: There is a tendency of the PC-MRI to underestimate the flow measured by the TTUS probes. The TTUS probe measures are more predictive of relevant post-hepatectomy outcomes. | Mohamed Bekheit Chloe Audebert Petru Bucur Hans Adriaensen Emilie Bled Mylène Wartenberg Irene Vignon-Clementel Eric Vibert | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，6： | 3 |
| 2 | A randomized,prospective,controlled,multicenter clinical trial of a sprayable,site-specific adhesion barrier system in patients undergoing myomectomy显示文摘 | Mettler L Audebert A Lehmann-Willenbrock E | | 0，，02： | 1 |
| 3 | Use of the 3,H2AX assay for assessing the genotoxicity of polycyclic aromatic hydro- carbons in human cell lines显示文摘 | AUDEBERT M RIU A JACQUES C | 2010 | Toxicol Lett2010，199，2： | 1 |
| 4 | Progression in lacunar stroke is related to elevated acute phase parameters显示文摘 | Audebert HJ Pellkofer TS Wimmer ML | 2004 | Eur Neurol2004，51，3： | 1 |
| 5 | Progression in lacunar stroke is releted to e|evated acute phase parameters显示文摘 | Audebert HJ Pellkofer TS Wimmer ML | 2004 | Eur Neurol2004，51，3： | 1 |
| 6 | Validation of high- throughput genotoxicity assay screening using ',/H2AX in-cell western assay on HepG2 cells 显示文摘 | KHOURY L ZALKO D AUDEBERT M | 2013 | Environment Mol Mutagen2013，54，9： | 1 |
| 7 | Swelling of anionic and cationic starch-based superabsorbents in water and saline solution 显示文摘 | Castal D Ricard A Audebert R | 1990 | J Appl Polym Sci1990，39，1： | 1 |
| 8 | Junctional recruitment of mammalian Scribble relies on E-cadherin engagement显示文摘 | Navarro C Nola S Audebert S | 2005 | Oncogene2005，24，： | 1 |
| 9 | Progression in lacunar Stroke is related to elevated acute phase parameters 显示文摘 | Audebert HJ Pellkofer TS Wimmer ML | 2004 | Eur Neurol2004，51，3： | 1 |
| 10 | Insights into migration in the angle domain显示文摘 | AUDEBERT F FROIDEVAUX P RACOTOARISOA H | 2002 | Expanded Abstracts of 72nd Annual Internat SEG Mtg2002，，： | 1 |
| 11 | 查看详情显示文摘 | Mabire F Audebert R Quivoron C | | 0，，09： | 1 |
| 12 | Thermal and compaction processes in a young rifted basin containing evaporites:Gulf of Lions,Francc显示文摘 | Burrus J Audebert F | 1990 | AAPG Bulletin1990，74，9： | 1 |
| 13 | Progression in lacunar stroke is related to elevated acute phase parameters显示文摘 | Audebert HJ Pellkofer TS Wimmer ML | 2004 | Eur Neurol2004，51，3： | 1 |
| 14 | Progression in lacuna stroke is related to elevated acute phase parameters显示文摘 | AUDEBERT H J PELLKOFER T S WIMMER M L | 2004 | Eur Neurol2004，51，3： | 1 |
| 15 | Reversible thermothickening of aqueous polymer solutions显示文摘 | HOURDET D L' AIIORET F AUDEBERT R | 1994 | Polymer1994，35，12： | 1 |
| 16 | Progressiom in lacunar stroke is relatedto elevated acute phase parameters显示文摘 | Audebert HJ Pellkofer TS Wimmer ML | 2004 | Eur Neurol2004，51，3： | 1 |
| 17 | Reversible thermothickening of aqueous polymer solutions 显示文摘 | HOURDET D L' ALLORET F AUDEBERT R | 1994 | Polymer1994，35，： | 1 |
| 18 | Pre or postoperative medical treatment with nafarelin in stageⅢ-Ⅳ endometriosis:a French multicenter study显示文摘 | AUDEBERT A DESCAMPS P MARRET H | 1998 | Eur J Obstet Gynecol Reprod Biol1998，79，2： | 1 |
| 19 | Systemic inflammatory response depends on initial stroke severity but is attenuated by successful thrombolysis 显示文摘 | Audebert HJ Rott MM Eck T | 2005 | Stroke2005，36，2： | 1 |
| 20 | Synthesis of thermoassociative copolymers显示文摘 | HOURDET D L' AIIORET F AUDEBERT R | 1997 | Polymer1997，38，10： | 1 |
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