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| 1 | Photodynamic therapy vs radiofrequency ablation for Barrett's dysplasia: Efficacy,safety and cost-comparison显示文摘AIM:To compare effectiveness,safety,and cost of photodynamic therapy(PDT)and radiofrequency ablation(RFA)in treatment of Barrett’s dysplasia(BD).METHODS:Consecutive case series of patients undergoing either PDT or RFA treatment at single center by a single investigator were compared.Thirty-three patients with high-grade dysplasia(HGD)had treatment with porfimer sodium photosensitzer and 630 nm laser(130 J/cm),with maximum of 3 treatment sessions.Fifty-three patients with BD(47 with low-grade dysplasia-LGD,6 with HGD)had step-wise circumferential and focal ablation using the HALO system with maximum of 4 treatment sessions.Both groups received proton pump inhibitors twice daily.Endoscopic biopsies were acquired at 2 and 12 mo after enrollment,with 4-quadrant biopsies every 1 cm of the original BE extent.A complete histological resolution response of BD(CR-D)was defined as all biopsies at the last endoscopy session negative for BD.Fisher’s exact test was used to assess differences between the two study groups for primary outcomes.For all outcomes,a two-sided P value of less than 0.05 was considered to indicate statistical significance.RESULTS:Thirty(91%)PDT patients and 39(74%)RFA were men(P=0.05).The mean age was 70.7±12.2 and 65.4±12.7(P=0.10)year and mean length of BE was 5.4±3.2 cm and 5.7±3.2 cm(P=0.53)for PDT and RFA patients,respectively.The CR-D was(18/33)54.5%with PDT vs(47/53)88.7%with RFA(P=0.001).One patient with PDT had an esophageal perforation and was managed with non-surgical measures and no perforation was seen with RFA.PDT was five times more costly than RFA at our institution.The two groups were not randomized and had different BD grading are the limitations of the study.CONCLUSION:In our experience,RFA had higher rate of CR-D without any serious adverse events and was less costly than PDT for endoscopic treatment of BD. | Atilla Ertan Irum Zaheer Arlene M Correa Nirav Thosani Shanda H Blackmon | 2013 | World Journal of Gastroenterology2013，19，41： | 7 |
| 2 | 前房注射头孢呋辛对术后眼内炎的预防作用(英文)显示文摘目的:研究前房注射头孢呋辛对术后眼内炎的预防作用。方法:回顾性研究6 099例行超声乳化白内障手术的年龄相关性白内障患者。对照组,2001-10/2004-05,3 075例3 075眼行白内障手术未用眼内抗生素,实验组,2004-06/2007-04,3 024例3 024眼术中前房用0.1mL含1mg的头孢呋辛。两组的术前预防措施和手术步骤相同。结果:对照组和实验组分别有13(0.42%)和4(0.13%)例患者发生术后眼内炎[P=0.031;OR =3.20(1.04-9.84)]。两组发生术后眼内炎的平均时间分别是术后30(3 ~75)d和25(2 ~35)d(P=0.35)。研究细菌感染,实验组,烟曲菌和铜绿假单胞菌对头孢呋辛耐药,而肺炎链球菌对头孢呋辛敏感。未发现前房运用头孢呋辛的毒性和过敏性症状。结论:预防性前房运用头孢呋辛是安全的,可以预防术后细菌性眼内炎。然而抗生素抗菌谱窄和抗生素耐药性的可能性需要考虑。 | Güngr Sobaci Yusuf Uysal Fatih M Mutlu Atilla Bayer Rιza Gungor Suat Karagul | 2009 | 国际眼科杂志2009，9，8： | 2 |
| 3 | Mechanistic transformations involving living and controlled/living polymerization methods显示文摘 | YUSUF Y ATILLA T M | 2006 | Progress in Polymer Science2006，31，12： | 1 |
| 4 | Rate of metoclopramide infusion affects the severity and incidence of akathisia显示文摘 | PARLAK I ATILLA R CICEK M | 2005 | Emerg Med J2005，22，9： | 1 |
| 5 | Spinal canal remodeling in burst fractures of the thoracolumbar spine : a computerized tomographic comparison between operative and nonoperative treatment 显示文摘 | Yazici M Atilla B Tepe S | 1996 | J Spinal Disord1996，9，5： | 1 |
| 6 | Thwaites' diagnostic scoring and the prediction of tuberculous meningitis 显示文摘 | Sunbul M Atilla A Esen S | 2005 | Med Princ Pract2005，14，3： | 1 |
| 7 | A new progress-based method- ology for analysis of shale smears along normal faults in the Ni- ger delta 显示文摘 | Kaledoye A K Atilla A Eric M | 2003 | AAPG Bulletin2003，87，3： | 1 |
| 8 | Spiral canal remodeling in burst fractures of the thoracolumbar spine: a computerized tomographic comparison between operative and nonoperative treatment显示文摘 | Yazici M Atilla B Tepe S | 1996 | J Spinal Disord1996，9，： | 1 |
| 9 | Synthesis and characterization of UV-curable dual hy- brid oligomers based on epoxy acrylate containing pendant alkoxysilane groups显示文摘 | Bayramoglu G Kahraman M V Kayaman A N Atilla G | 2006 | Progress in Organic Coat- ings2006，57，1： | 1 |
| 10 | Estrogen as a novel agent for induction ~f adipose-derived mesenchymal stem cells for osteo- genic differentiation: in vivo bone tissue-engineering study显示文摘 | Calis M Demirtas T T Atilla P | 2014 | Plast Reconstr Surg2014，133，4： | 1 |
| 11 | Thwaites' diagnostic scoring and the prediction of tuberculous meningitis显示文摘 | Sunbul M Atilla A Esen S | 2005 | Med Princ Pract2005，14，3： | 1 |
| 12 | The shape of the lumbar vertebral canal in newborns显示文摘 | Atilla B Yazici M Kopuz C | 1997 | Spine1997，22，21： | 1 |
| 13 | Manufacturing Low Den- sity Boards from Waste Cardboards Containing Aluminium 显示文摘 | ATILLA M AYSE S M METING | 2007 | Materials and Design2007，28，7： | 1 |
| 14 | Position of the acetabular component determines the fate of femoral head autografts in totalhip replacement for acetabular dysplasia 显示文摘 | Atilla B Ali H Aksoy M C | 2007 | J Bone Joint Surg Br2007，89，7： | 1 |
| 15 | Position of the ace- tabular component determines the fate of femoral head au- tografts in total hop replacement for acetabular dysplasia 显示文摘 | Atilla B Ali H Aksoy M C | 2007 | J Bone Joint Surg(Br)2007，89，7： | 1 |
| 16 | Serial magnetic resonance imaging of the West Nile Virus encephalitis显示文摘 | Atilla Arslanoglu Deepak Takhtani David M Yousem | 2003 | Radiology Extra2003，48，： | 1 |
| 17 | Spinal canal remodeling inburst fractures of the thoracolumbar spine : a computerizedtomographic comparison between operative and nonoperative treat-ment显示文摘 | Yazici M Atilla B Tepe S | 1996 | J Spinal Disord1996，9，5： | 1 |
| 18 | Characterization of strike-slip fault - splay relationships in sandstone 显示文摘 | Ghislain D J Ovunc M Atilla A | 2007 | Journal of Structural Geology2007，29，11： | 1 |
| 19 | Quantitive analysis of the drainage after neck dissection 显示文摘 | Levent E Gonca Y Atilla M | 2000 | Otolaryngol Head Neck Surg2000，123，3： | 1 |
| 20 | Surface morphology of columnar joints and its significance to mechanics and direction of joint growth 显示文摘 | Degraff J M Atilla Aydin | 1987 | Geological Society of America1987，99，： | 1 |
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