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1国际糖尿病足工作组:糖尿病足感染诊断与治疗指南——《国际糖尿病足工作组:糖尿病足防治国际指南(2019)》的一部分显示文摘国际糖尿病足工作组(IWGDF)从1999年开始发布糖尿病足病防治指南。本指南是有关糖尿病足感染的诊断和治疗的指南,是在2015年糖尿病足感染指南基础上更新的。糖尿病足感染指南编辑委员会基于患者-干预-比较-结局(PICO)原则,整合内部与外部专家顾问的建议,并对2016年以后有关糖尿病足感染和处治的文献进行系统评价后,提出了27条推荐要点。这些推荐要点涵盖了软组织与骨组织感染的诊断,包括感染的严重性分级。这是IWGDF15年以来第一次对这个分级表进行更新。此外,指南还评估了糖尿病足感染的微生物学,包括如何收集标本及如何识别致病菌。最后,指南讨论了治疗糖尿病足感染的方法,包括经验性抗生素的选择、软组织和骨组织感染的抗微生物治疗、何时和如何进行外科处理以及各种辅助治疗对糖尿病足感染的有效性。本版指南在原指南的基础上更新了4个表格和1个图。我们认为该指南可以为糖尿病足感染的临床诊断和治疗提供更好的帮助。Benjamin A.Lipsky Eric Senneville Zulfqarali G.Abbas Javier Aragón-Sánchez Mathew Diggle John M.Embil Shigeo Kono Lawrence A.Lavery Matthew Malone Suzanne A.van Asten Vilma Urbancic-Rovan Edgar J.G.Peters 徐俊(译) 许樟荣(审校) 2019感染.炎症.修复2019,20,4:18
2难加工材料的铣削和钻削加工显示文摘当前,减轻飞机重量这一目标正在促使航空航天工业采用越来越多的特种材料,如复合材料、钛合金和铬镍铁合金。相比普通材料,此类材料重量更轻、强度更高,但在加工方面,特别是铣削和钻削方面,它们各自拥有不同的加工难题。Teun Van Asten Wilco van den Boogaard Pr Nordberg 2013航空制造技术2013,56,14:2
3Decreased ankle - brachial indices in relation to morbidity and mortality in patients with peripheral arterial disease 显示文摘Sikkink CJ Van Asten WN Vant Hof MA 1997Vasc Med1997,2,:1
4Biological monitoring the exposure to polycyclic aromatic hydrocarbons of coke oven workers in relation to smoking and genetic polymorphisms for GSTM1 and GSTT1显示文摘van Delft J H M Steenwinkel M van Asten J G 2001Annals of Occupational Hygiene2001,45,5:1
5Influence of water vapor and flow rate on the high temperature oxidation of 304L: effect of chromium oxide hydrox ide evaporation 显示文摘Asten H Svensson J E Norel M 2000Oxidation of Metals2000,54,1:1
6Biological monitoring the exposure to polycyclic aromatic hydrocarbons of coke oven workers in relation to smoking and genetic pnlymorphisms for GSTM1 and GSTT1 显示文摘VAN DELFT JH STEENWINKEL MS VAN ASTEN JG 2001Ann Occup Hyg2001,45,5:1
7Decreased ankle/brachial indices in relation to morbidity and mortality in patients with peripheral arterial disease显示文摘Sikkink CJ van Asten WN var't Hof MA 1997Vase Med1997,2,3:1
8Syndromic surveillance for local outbreaks of lower-respiratory infections: would it work? 显示文摘Van Den Wijngaard CC Van Asten L Van Pelt W 2010PLoS One2010,5,4:1
9Risk factors for typhoid and paratyphoid fever in Jakarta, Indonesia 显示文摘Vollaard AM All S van Asten HA 2004JAMA2004,291,21:1
10Decreased ankle/brachial indices in relation to morbidity and mortality in patients with peripheral arterial disease显示文摘Sikkink CJ van Asten W N van I Hof MA 1997Vase Med1997,2,3:1
11Fast approximate solutions of transient EM response to a target buried beneath a conductive overburden显示文摘LIU G M ASTEN M W 1993Geophysics1993,58,6:1
12Decreased ankle/brachial indices in relation to morbidity and mortality in patients with peripheral arterial disease显示文摘Sikkink CJ van Asten WN van't Hof MA 1997Vasc Med1997,2,:1
13A randomised controlled trial of care of the perineum during second stage of normal labour 显示文摘McCandlish R Bowler U van Asten H 1995Br J Obstet Gynaecol1995,105,12:1
14High resolution magic angle spinning NMR spectroscopy for metabolic assessment of cancer presence and Gleason score in human prostate needle biopsies显示文摘van Asten JJ Cuijpers V Hulsbergen-vande Kaa C 2008MAGM2008,21,6:1
15Improved injection practices after the introduction of treatment and sterility guidelines in Tanzania显示文摘Vos J Gumodoka B Van Asten HA 1998Trop Med Int Health1998,3,4:1
16Short mucin 6 alleles are associated with H pylori infection显示文摘AIM: To investigate the relationship between mucin 6 (MUC6) VNTR length and H pylori infection. METHODS: Blood samples were collected from patients visiting the Can Tho General Hospital for upper gastrointestinal endoscopy. DNA was isolated from whole blood, the repeated section was cut out using a restriction enzyme (PvuⅡ) and the length of the allelefragments was determined by Southern blotting. H pylori infection was diagnosed by 14C urea breath test. For analysis, MUC6 allele fragment length was dichotomized as being either long (> 13.5 kbp) or short (≤ 13.5 kbp) and patients were classif ied according to genotype [long- long (LL), long-short (LS), short-short (SS)].RESULTS: 160 patients were studied (mean age 43 years, 36% were males, 58% H pylori positive). MUC6 PvuⅡ-restricted allele fragment lengths ranged from7 to 19 kbp. Of the patients with the LL, LS, SS MUC6 genotype, 43% (24/56), 57% (25/58) and 76% (11/46) were infected with H pylori, respectively (P = 0.003).CONCLUSION: Short MUC6 alleles are associated with H pylori infection.Thai V Nguyen Marcel JR Janssen Paulien Gritters René HM te Morsche Joost PH Drenth Henri van Asten Robert JF Laheij Jan BMJ Jansen 2006World Journal of Gastroenterology2006,12,37:1
17Decreased ankle/brachial indices in relation to morbidity and mortality in patients with peripheral arterial disease显示文摘Sikkink C J van Asten WN rarr' t Hof MA 0,,03:1
18Predisposing factors and prevention of Clostridium perfringens: associated enteritis显示文摘ALLAART J G van ASTEN A J A M GRONE A 2013Comparative Immunology Microbiology and Infectious Diseases2013,36,5:1
19Decreased ankle-brachial indices in relation to morbidity and mortality inpatients with peripheral arterial disease显示文摘Sikkink C J van Asten W N van't Hof M A 1997Vasc Med1997,2,:1
20Decreased ankle -brachial indices in relation to morbidity and mortality in patients with peripheral arterial disease显示文摘Sikknik CJ Van Asten WN Vant Hof MA 1997Vasc Med1997,2,3:1
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