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| 1 | Bone marrow-derived monocyte infusion improves hepatic fibrosis by decreasing osteopontin,TGF-β1,IL-13 and oxidative stress显示文摘AIM To evaluate the therapeutic effects of bone marrowderived CD11b+CD14+ monocytes in a murine model of chronic liver damage. METHODS Chronic liver damage was induced in C57BL/6 mice by administration of carbon tetrachloride and ethanol for 6 mo. Bone marrow-derived monocytes isolated by immunomagnetic separation were used for therapy. The cell transplantation effects were evaluated by morphometry,biochemical assessment,immunohistochemistry and enzyme-linked immunosorbent assay. RESULTS CD11b+CD14+ monocyte therapy significantly reduced liver fibrosis and increased hepatic glutathione levels. Levels of pro-inflammatory cytokines,including tumor necrosis factor-α,interleukin(IL)-6 and IL-1β,in addition to pro-fibrotic factors,such as IL-13,transforming growth factor-β1 and tissue inhibitor of metalloproteinase-1 also decreased,while IL-10 and matrix metalloproteinase-9 increased in the monocytetreated group. CD11b+CD14+ monocyte transplantation caused significant changes in the hepatic expression of α-smooth muscle actin and osteopontin. CONCLUSION Monocyte therapy is capable of bringing about improvement of liver fibrosis by reducing oxidative stress and inflammation,as well as increasing antifibrogenic factors. | Veruska Cintia Alexandrino de Souza Thiago Almeida Pereira Valéria Wanderley Teixeira Helotonio Carvalho Maria Carolina Accioly Brelaz de Castro Carolline Guimaraes D’assuncao Andreia Ferreira de Barros Camila Lima Carvalho Virgínia Maria Barros de Lorena Vláudia Maria Assis Costa Alvaro Aguiar Coelho Teixeira Regina Celia Bressan Queiroz Figueiredo Sheilla Andrade de Oliveira | 2017 | World Journal of Gastroenterology2017，23，28： | 6 |
| 2 | 三维网络结构氧化铜纳米线锂离子电池负极材料的制备和性能研究显示文摘通过阳极氧化法和后退火处理在铜箔上合成了三维网络结构氧化铜纳米线,将其作为负极材料制备了无需添加粘结剂的锂离子电池。研究了恒压氧化时间对材料形貌和电化学性能的影响。在1C的倍率下,氧化1000 s制备的CuO纳米线表现出最高的1172 mAh/g首圈放电比容量和594 mAh/g的可逆比容量,500圈循环可逆比容量为607.6 mAh/g,可逆容量保留率为102.3%。交联的三维网络结构CuO纳米线相互支撑,提供稳定的结构,有效缓解了CuO纳米线作为锂离子电池负极材料中的体积膨胀问题,表现出了优异的倍率性能和循环寿命。 | 曹宇光 肖煌 周佳盈 高云 Manon D'Assuncao Lourenco Kevin Peter Homewood 鲍钰文 夏晓红 | 2020 | 功能材料2020，51，4： | 3 |
| 3 | Buffer analysis and control in CBR video transcoding 显示文摘 | Assuncao P A A Ghanbari M | 2000 | IEEE Transactions on Circuits and Systems for Video Technology2000，10，1： | 2 |
| 4 | Protective effects of chronic green tea consumption on age-related neurodegeneration 显示文摘 | Andrade JP Assuncao M | 2012 | Curr Pharm Des2012，18，： | 1 |
| 5 | Contextswhich shape and reshape new teachePs' identities显示文摘 | Ma Pia Assuncao Floresa ChPisl opheP Day | 2006 | Teaching and TeacheP Education2006，，22： | 1 |
| 6 | Performance and Computational Complexity Assessment of High- Efficiency Video Encoders 显示文摘 | Correa G Assuncao P Agostini L | 2012 | IEEE Transactions on Circuits and Sys- tems for Video Technology2012，22，12： | 1 |
| 7 | Blending PSO and ANN for optimal design of FSS filters with Koch Island patch elements 显示文摘 | Da F Silva P H Cruz R M S D' Assuncao A G | 2010 | IEEE Trans on Magnetics2010，46，8： | 1 |
| 8 | Contexts which shape and reshape new teachers' identities显示文摘 | Maria Assuncao Floresa Christopher Day | 2006 | Teahing and Teacher Education2006，，22： | 1 |
| 9 | A cost-benefitanalysis of using cloud computing to extend the capacityof clusters显示文摘 | de Assuncao M D di Costanzo A Buyya R | 2010 | Journal of Cluster Computing2010，13，3： | 1 |
| 10 | Evaluation of Mycoplasma hyopneumoniae growth by flow cytometry 显示文摘 | Assuncao P Diaz R Comas J | 2005 | J Appl Microbiol2005，98，5： | 1 |
| 11 | The effect of different doses of propofol on tracheal intubation conditions without muscle relaxant in child显示文摘 | De Fatima De Assuncao BragaA Da SilvaBraga FS Poterio GM | 2001 | EurJAneasthesiol2001，18，6： | 1 |
| 12 | 显示文摘 | Fortunato E Goncalves A Assuncao V | 2003 | Thin Solid Films2003，442，： | 1 |
| 13 | Carotenoids and ascorbic acid composition from commercial products of cashew apple 显示文摘 | Assuncao R B Mercadante A Z | 2003 | Journal of Food Composition and Analysis2003，16，64： | 1 |
| 14 | Emission of polycyclic aromatic hydrocarbons from light-duty diesel vehicles exhaust显示文摘 | De ABRANTES R De ASSUNCAO J V PESQUERO C R | 2004 | Atmospheric Environ2004，38，11： | 1 |
| 15 | Octyl and dodecy gallates induce oxidative stress and apoptosis in a melanoma cell line 显示文摘 | de Cordova CA Locatelli C Assuncao LS | 2011 | Toxicol In Vitro2011，25，8： | 1 |
| 16 | Weight gain management in patients with schizophrenia during treatment with olanzapine in association with nizatidine显示文摘 | Assuncao SS Ruschel SI Rosa L C | 2006 | Rev Bras Psiquiatr2006，28，4： | 1 |
| 17 | Clenbuterol Food Poisoning Diagnosis by Gas Chromatography-Mass Spectrometric Serum Analysis显示文摘 | Fernando R Assuncao C R Paulo C | 2003 | Analytica Chimica Acta2003，483，： | 1 |
| 18 | The oc- currence of mycoplasmas in the lungs of swine in Gran Cana-ria(Spain) 显示文摘 | ASSUNCAO P DE LA FE C KOKOTOVIC B | 2005 | Vet Re5 Commun2005，29，6： | 1 |
| 19 | Myocardial dysfu- nction in sepsis: a large, unsolved puzzle 显示文摘 | Fernandes CJ Jr de Assuncao MS | 2012 | Crit Care Res Pract2012，，89： | 1 |
| 20 | Myocardial dysfunction in sepsis: a large, unsolved puzzle 显示文摘 | Fernandes CJ de Assuncao MS | 2012 | Crit Care Res Pract2012，7，89： | 1 |
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