3篇
您的检索式：作者名="Ashish Chogle"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pediatric IBS: An Overview on Pathophysiology, Diagnosis and Treatment显示文摘 | Chogle Ashish Mintjens Stijn Saps Miguel | 2014 | Pediatric Annals2014，，4： | 1 |
| 2 | A Million-dollar Work-up for Abdominal Pain: Is It Worth It?显示文摘 | Gati Dhroove Ashish Chogle Miguel Saps | 2010 | Journal of Pediatric Gastroenterology and Nutrition2010，，5： | 1 |
| 3 | Electrocardiograms changes in children with functional gastrointestinal disorders on low dose amitriptyline显示文摘AIM: To study the effects of low dose amitriptyline on cardiac conduction in children.METHODS: Secondary analysis of data obtained from a double-blind, randomized placebo-controlled trial, evaluating low dose amitriptyline in children with a diagnosis of functional abdominal pain, functional dyspepsia, and irritable bowel syndrome according to the Rome II criteria. Children 8-17 years of age were recruited from the pediatric gastroenterology clinics of 6 tertiary care centers in the United States. The electrocardiograms(EKGs) done prior to initiation of amitrityline and 1 mo after initiation of amitriptyline were examined. The changes in cardiac conduction were evaluated in patients and controls. RESULTS: Thirty children were included in the study. There were 12 patients, ages 9-17 years of both genders, in the amitriptyline treatment group and 18 patients, ages 9-17 years of both genders, in the placebotreatment group. None of the patients had any baseline EKG abnormality. Amitriptyline use was associated with an increase in heart rate(P = 0.024) and QTc interval(P = 0.0107) as compared to pre-EKGs. Children in the placebo group were also noted to present a statistically significant increase in QTc interval(P = 0.0498). None of the patients developed borderline QTc prolongation or long-QT syndrome after they were started on amitriptyline.CONCLUSION: The study findings suggest that once patients with functional gastrointestinal disorders have been screened for prolonged QTc interval on baseline EKG, they probably do not need a second EKG for reevaluation of cardiac conduction after starting low dose amitriptyline. | Ashish Chogle Miguel Saps | 2014 | World Journal of Gastroenterology2014，20，32： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员