|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Radical vs conservative surgery for hydatid liver cysts:Experience from single center显示文摘AIM:To compare the efficacy and safety of radical and conservative surgical interventions for liver hydatid disease.METHODS:The study comprised 59 patients in two groups who had undergone radical and conservative surgical procedures for liver hydatid disease in our department between 2004 and 2009. Preoperative diagnostic tools,medical treatments,demographic and clinical characteristics,postoperative follow-up,and recurrence were compared in both groups. RESULTS:This non-randomized retrospective studyincluded 59 patients who had undergone liver hydatid disease surgery. The radical technique was used in 18 patients (mean age:42.1 ± 13.5 years,seven male,11 female),and the conservative technique was used in 41 patients (mean age:43.5 ± 13.9 years,17 male,24 female). The follow-up period ranged from 3 to 58 mo. Although operative time was significantly shorter in the conservative group (P < 0.001),recurrence was significantly reduced in the radical group (P = 0.045). No statistically significant differences were found in terms of hospitalization duration,cyst count and size,location,postoperative complications,scolicidal solution usage,or follow-up duration between the two groups.CONCLUSION:The more effective method for pre-venting postoperative recurrence is radical surgery. En-doscopic retrograde cholangiopancreatography for bile leakage in the early postoperative period may decrease the requirement for repeat surgery. | Sami Akbulut Ayhan Senol Arsenal Sezgin Bahri Cakabay Mehmet Dursun Omer Satici | 2010 | World Journal of Gastroenterology2010，16，8： | 19 |
| 2 | Inhibition of focal adhesion kinase enhances antitumor response of radiation therapy in pancreatic cancer through CD8+ T cells显示文摘Objective:Pancreatic ductal adenocarcinoma(PDAC)is a deadly malignancy,due in large part to its resistance to conventional therapies,including radiotherapy(RT).Despite RT exerting a modest antitumor response,it has also been shown to promote an immunosuppressive tumor microenvironment.Previous studies demonstrated that focal adhesion kinase inhibitors(FAKi)in clinical development inhibit the infiltration of suppressive myeloid cells and T regulatory(T regs)cells,and subsequently enhance effector T cell infiltration.FAK inhibitors in clinical development have not been investigated in combination with RT in preclinical murine models or clinical studies.Thus,we investigated the impact of FAK inhibition on RT,its potential as an RT sensitizer and immunomodulator in a murine model of PDAC.Methods:We used a syngeneic orthotopic murine model to study the effect of FAKi on hypofractionated RT.Results:In this study we showed that IN10018,a small molecular FAKi,enhanced antitumor response to RT.Antitumor activity of the combination of FAKi and RT is T cell dependent.FAKi in combination with RT enhanced CD8+T cell infiltration significantly in comparison to the radiation or FAKi treatment alone(P<0.05).FAKi in combination with radiation inhibited the infiltration of granulocytes but enhanced the infiltration of macrophages and T regs in comparison with the radiation or FAKi treatment alone(P<0.01).Conclusions:These results support the clinical development of FAKi as a radiosensitizer for PDAC and combining FAKi with RT to prime the tumor microenvironment of PDAC for immunotherapy. | Arsen Osipov Alex B.Blair Juliane Liberto Jianxin Wang Keyu Li Brian Herbst Yao Xu Shiqi Li Nan Niu Rufiaat Rashid Ding Ding Yanan Liu Zaiqi Wang Christopher L.Wolfgang Richard A.Burkhart Daniel Laheru Lei Zheng | 2021 | Cancer Biology & Medicine2021，18，1： | 3 |
| 3 | 冠心病患者接受大型非心脏外科手术前12导联心电图的远期预后价值显示文摘Background: Knowledge of the prognostic information of preoperative 12- lead electrocardiogram(ECG) recordings in patients with coronary artery disease(CAD) undergoing noncardiac surgery is limited. Methods: The prognostic information derived from the preoperative ECGs of 172 CAD patients undergoing major noncardiac surgery was analyzed to determine its predictive value for long- term outcome. Primary end point was all- cause mortality; secondary end point was major adverse cardiac events(MACE) at 2 years. Results: Prevalence of ECG abnormalities was 53% for T- wave alterations; 46% for Q waves; 38% for ST deviations; and, depending on the criterion used, 2% to 19% for left ventricular hypertrophy. During follow- up, 40(23% ) patients died and 31(18% ) had MACE. After adjustment for clinical baseline findings, including current medication with β - blockers, ST depressions(odds ratio [OR] 4.5, 95% confidence interval [CI] 1.9- 10.5) and faster heart rate(HR)(OR 1.6, 95% CI 1.1- 2.4, per 10 beats per minute [bpm] increase) were independent predictors of all- cause mortality. Faster HR(OR 1.7, 95% CI 1.1- 2.6, per 10- bpm increase) was also an independent predictor of MACE. The predictive value of ECG variables did not change after adjustment for occurence of perioperative ischemia. Conclusion: In CAD patients, the preoperative ECG contains important prognostic information and is predictive of long- term outcome independent of clinical findings and perioperative ischemia. | Jeger R. V. Probst C. Arsenic R. M. Filipovic 赵君(译) 任付先(校) | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，2，6： | 2 |
| 4 | 显示文摘 | Ute Kuballa Jurgen Jantzen Eckard Simultaneous separation of 17 inorganic and organic arsenic compounds in marine biota by means of high-performance liquid chromatography/inductively coupled plasma mass spectrometry | 2000 | Rapid Communications in Mass Spectrometry2000，16，10： | 1 |
| 5 | Catalytic wet hydrogen peroxide oxidation of para-chlorophenol o- ver A1/Fe pillared clays (AIFePILCs) prepared from different host clays显示文摘 | Catrinescu C Arsene D Teodosiu C | 2011 | Applied Catalysis B: Envirnmental2011，101，： | 1 |
| 6 | Education and Agricultural Productivity:Evidence from Uganda显示文摘 | Appleton Simon Arsene Balihuta | | 0，，03： | 1 |
| 7 | 显示文摘 | A Determination of total cationic a total anionic arsenic species in oyster tissue usi microwave-assisted extraction followed HPLC-ICP-MS | 2000 | Talanta2000，51，2： | 1 |
| 8 | 显示文摘 | Cezar Catrinescu Daniela Arsene Carmen Teodosiu | 2011 | Ap- plied Catalysis B: Environmental2011，101，34： | 1 |
| 9 | Ceiling mounted personalized ventilation system in hot and humid climate- an energy analysis显示文摘 | Bin Yang Chandra Sekhar Arsen K Melikov | 2010 | Energy and Buildings2010，42，： | 1 |
| 10 | Array com parative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinoma显示文摘 | Sriram KB I arsen J E Savarimuthu Francis SM | 2012 | PLoS One2012，7，30： | 1 |
| 11 | Energy-saving strategies with personalized ventilation in cold climates 显示文摘 | Stefano Schiavon Arsen K Melikov | 2009 | Energy and Buildings2009，41，： | 1 |
| 12 | Catalytic wet hydrogen peroxide oxidation of para- chlorophenol over Al/Fe pillared days (AlFePILCs) prepared from different host days显示文摘 | Catrinescu C Arsene D Teodosiu C | 2011 | Ap- plied Catalysis B: Environmental2011，101，34： | 1 |
| 13 | Catalytic wet hydrogen peroxide oxidation of para-chlorophenol over Al/Fe pillared clays(AlFePILCs) prepared from different host clays显示文摘 | Catrinescu C Arsene D Teodosiu C | 2011 | Applied Catalysis B:Envi-ronmental2011，101，34： | 1 |
| 14 | 7M NaCl solution显示文摘 | Yan Gao and Alfonso Mucci Acid base reactions phosphate and arsenate complexation and their competitive adsorption at the surface of goethite in 0 | 2001 | Geachimica et Casmochimica Acta2001，65，14： | 1 |
| 15 | A new approach to measuring transverse properties of structural tubing by a ring test 显示文摘 | Arsene S Bai J | 1996 | J Testing and Evaluation1996，24，6： | 1 |
| 16 | The concept of sustainable urban water management显示文摘 | I ARSEN T GUJER W | 1996 | War Sci Tech1996，35，9： | 1 |
| 17 | A new approach to measuring transverse properties of structural tubing by a ring test: Experimental investigation 显示文摘 | Arsene S Bai J | 1998 | J Testing and Evaluation1998，26，1： | 1 |
| 18 | C677T and A1298C methylenetetrahydropholate reductase (MTHFR) polymorphisms as factors involved in ischemic stroke显示文摘 | Arsene D Gaina G Balescu C | 2011 | Rom J Morphol Embryol2011，52，4： | 1 |
| 19 | Comparison of limbal-conjunctival autograft and intraoperative 0.02% mitomycin-C for treatment of primary pterygium显示文摘 | Arsen Akinci Orhan Zilelioglu | 2007 | International Ophthalmology2007，，5： | 1 |
| 20 | An unusual cause ofileal perforation:Report of a case and literature review显示文摘An ileal perforation resulting from a migrated biliary stent is a rare complication of endoscopic stent placement for benign or malignant biliary tract disease.We describe the case of a 59-year-old woman with a history of abdominal surgery in which a migrated biliary stent resulted in an ileal perforation.Patients with comorbid abdominal pathologies,including colonic diverticuli,parastomal hernia,or abdominal hernia,may be at increased risk of perforation from migrated stents. | Sami Akbulut Bahri Cakabay Cihan Akgul Ozmen Arsenal Sezgin Mahsuni Mert Sevinc | 2009 | World Journal of Gastroenterology2009，15，21： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员