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| 1 | Diagnostic accuracy of enhanced liver fibrosis test to assess liver fibrosis in patients with chronic hepatitis C显示文摘BACKGROUND:The prognosis and clinical management of patients with chronic liver diseases are closely related to the severity of liver fibrosis.Liver biopsy is considered the gold standard for the staging of liver fibrosis.However,it is an invasive test sometimes related to complications.This study aimed to assess the diagnostic value of enhanced liver fibrosis(ELF) test to predict liver fibrosis in patients with chronic hepatitis C.METHODS:This study included 162 patients with liver disease and 67 healthy controls.Hyaluronic acid,tissue inhibitor of matrix metalloproteinase type 1,and amino-terminal propeptide type III procollagen were measured by enzymelinked immunosorbent assay with the ELF test ADVIA Centaur(Siemens Healthcare Diagnostics Inc.).Fibrosis stage was determined using the Metavir scoring system.RESULTS:In our study,for the diagnosis of significant fibrosis(Metavir F≥2) a cut-off value >7.72 provides a sensitivity of 93.0% and a specificity of 83.0%.The areas under the receiver operator characteristic curve,sensitivity,specificity,and positive and negative predictive values were 0.94,93.3%,81.0%,93.3%,and 81.0%,respectively(P<0.001).For the diagnosis of cirrhosis(Metavir F=4) a cut-off value >9.3 provides a sensitivity of 93.0% and a specificity of 86.0%.The areas under the receiver operator characteristic curve,sensitivity,specificity,and positive and negative predictive values were 0.94,79.1%,90.8%,75.6%,and 92.3%,respectively(P<0.001).CONCLUSIONS:The ELF test is a promising non-invasive method for assessing liver fibrosis in patients with chronic hepatitis C.It is effective in the diagnosis of both fibrosis and cirrhosis. | Roberto Catanzaro Michele Milazzo Silvia Arona Chiara Sapienza Dario Vasta Domenico Arcoria Francesco Marotta | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 3 |
| 2 | Diagnosis of chronic manganese intoxication by magnetic resonance imaging显示文摘 | Arona A Mata M Bonet M | 1997 | New Engl J Med1997，336，13： | 1 |
| 3 | Differences in Prevalence of Urinary Incontinence by Race/Ethnicity显示文摘 | David H. Thom Stephen K. van den Eeden Arona I. Ragins Christina Wassel-Fyr Eric Vittinghof Leslee L. Subak Jeanette S. Brown | 2006 | The Journal of Urology2006，，： | 1 |
| 4 | Information-theory measure of uncertainty for rough sets and rough relational databases显示文摘 | Beaubouef T Perry F E Arona G | 1998 | Inform Sci1998，109，： | 1 |
| 5 | Efficacy and safety of sitagliptin in patients with type 2 diabetes and ESRD receiving di- alysis : a 54 - week randomized trial 显示文摘 | Arona FJ Corry D Mogensen CE | 2013 | Am J Kidney Dis2013，61，4： | 1 |
| 6 | Diagnosis of chronic manganese intoxication by magnetic resonance imaging 显示文摘 | ARONA A MATA M BONET M | 1997 | New Engl J Med1997，336，13： | 1 |
| 7 | Membrane biodiesel production and refining technology:A critical review显示文摘 | Atadashi I Arona M Abdul Aziz A | 2011 | Renewable and Sustainable Energy Reviews2011，15，9： | 1 |
| 8 | Role of tyrosine kinase inhibitors in cancer therapy 显示文摘 | Arona A Scholar EM | 2005 | J Pharmacol Exp Ther2005，315，3： | 1 |
| 9 | The contribution of higher education to transformation, development and poverty reduction: Overview of the South African higher education context 显示文摘 | ARONA DISON MELANIE WALKER and MONICA MCLEAN | 2008 | BackgroundPaper2008，，： | 1 |
| 10 | Self and close relationships显示文摘 | ARONA | 2003 | Handbook of Self and Identity2003，，： | 1 |
| 11 | radioisotope Heat Source on the Moon,Isotop显示文摘 | Kelly D P Arona V A | 1970 | Radiate Technol1970，7，4： | 1 |
| 12 | Mean Kinematic Characteristics of Synoptic Easterly Disturbances over the Atlantic显示文摘This study investigates the mean kinematic characteristics of the tropical Atlantic easterly disturbances in January-March(JFM),April-June(AMJ),July-September(JAS)and October-December(OND)from 1968-1998.For each season,the preferential tracks of these disturbances in the 3-10-day band periods were computed and spatialized,as well as their associated wavelength,velocity and main period,which lies between 3-5 days and between 6-9 days depending on the track and the season. Two main tracks are highlighted over the Atlantic Ocean.During OND and JFM these two tracks are well separated and located in each hemisphere around 15°S and 12.5°N.From AMJ to JAS these tracks migrate northward;in JAS,they merge into one over the northern tropical Atlantic along 17.5°N.The associated wavelength fields exhibit a meridional gradient,with large wavelengths(greater than 4000 km) around the equator,between 5°N and 5°S,and smaller wavelengths outside of this latitude band(between 2500-3500 km).The phase speed is also found to exhibit poleward decreasing values from 12-6 m s-1. Over the north Atlantic track,6-9-day disturbances were found to occur from January to May and approximately from October to December.From June to September,the 3-5-day waves dominate the synoptic activity.Over the south Atlantic track,between May and August the synoptic variability is mainly explained by the 3-5-day disturbances but from January to April and from September to December both 3-5-day waves and 6-9-day waves can occur. | Arona DIEDHIOU Luiz A.T.MACHADO Henri LAURENT | 2010 | Advances in Atmospheric Sciences2010，27，3： | 0 |
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