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| 1 | 龙门山冲断带的隆升和川西前陆盆地的沉降显示文摘通过龙门山地区和川西前陆盆地岩石样品的裂变径迹和镜质体反射率的测定和计算机模拟得出:(1)松潘-甘孜褶皱带10Ma以来至少隆升了3—4km,隆升速率最低为0.3—0.4mm/a;(2)龙门山逆冲推覆构造带10Ma以来至少隆升了5—6km,隆升速率最低为0.5—0.6mm/a;(3)龙门山滑脱拆离带60Ma以来隆升1—2km,隆升速率为0.016—0.032mm/a;(4)川西前陆盆地60Ma以来隆升了1.7—3km,隆升速率为0.028—0.05mm/a;(5)10Ma以来北川—映秀—小关子断裂西侧的隆升速率是其东侧隆升速率的40倍;(6)60Ma以前松潘—甘孜褶皱带的隆升与川西前陆盆地的沉降曲线呈镜象关系,即松潘—甘孜褶皱带隆升较快时,盆地沉降也较快。60Ma以来,川西前陆盆地也以隆升为主,但松潘—甘孜褶皱带的隆升速率要大得多;(7)川西前陆盆地的古地温梯度为25℃/km。 | 刘树根 罗志立 戴苏兰 Dennis Arne C.J.L.Wilson | 1995 | 地质学报1995，69，3： | 163 |
| 2 | 中国的经济增长能否持续?——一个生产率视角显示文摘中国经济转型的渐进式方法产生了持续的高增长。然而,近年来中国的经济学家们越来越认为这种增长是“粗放式”的,主要是靠增加投入获得的。我们对中国改革时期的经济进行研究,发现改革的措施往往导致对全要素生产率(TFP)的一次性的水平效应。中国现在需要调整其改革方案以促进生产率的持续增长。市场与所有制的改革,以及开放政策,改善了中国企业的经营环境,但加强建设发展完善的市场经济,还需要更为深入的制度改革。 | 郑京海 胡鞍钢 Arne Bigsten | 2008 | 经济学(季刊)2008，7，2： | 178 |
| 3 | 龙门山造山带-川西前陆盆地系统构造事件研究显示文摘通过对构造事件形成的产物 (岩浆岩、各种矿物等 )进行氩 -氩年龄测定、裂变径迹年龄测定、ESR年龄测定和计算机模拟 ,得出龙门山造山带 -川西前陆盆地系统自印支期以来 ,共发生了 7次构造事件 :(1)卡尼期末的构造事件 (D1 ) ,形成 S1 和 F1 ,并有区域低温动热变质作用 ;(2 )诺利期末的构造事件 (安县运动 ,D2 ) ,产生川西前陆盆地上三叠统须四段与下伏地层不整合接触和须四段砾岩的分布 ,并有较强的岩浆作用 ;(3)燕山期 (12 0~ 130 Ma,D3) ,有较强的岩浆作用和变质作用 ;(4 )喜马拉雅期 6 0 Ma左右的构造事件 (D4) ;(5 )喜马拉雅期 30~ 40Ma的构造事件 (D5 ) ;(6 )喜马拉雅期 2 0~ 2 5 Ma的构造事件 (D6 ) ;(7)喜马拉雅期 10 Ma的构造事件 (D7)。后 4次构造事件使龙门山造山带 | 刘树根 赵锡奎 罗志立 徐国盛 王国芝 C.J.L.Wilson Dennis Arne | 2001 | 成都理工学院学报2001，28，3： | 99 |
| 4 | 1980—1994期间中国国有企业的效率、技术进步和最佳实践显示文摘本文在1980年到1994年的700个国有企业样本数据的基础上,采用数据包络法和Malmquist指数法,以生产率的增长为指标,考察了国有企业的生产绩效。与样本企业中的最佳实践企业相比,我们的经验研究结果表明,这些样本企业的技术效率普遍较低。尽管生产率增长引人注目,但这一增长主要是通过技术进步而不是通过提高技术效率。进一步的回归分析结果表明,大型国企生产率增长的概率明显高于小型企业。最佳实践企业存在于沿海省份的大型国企当中的概率也比较高。工资激励和职工学历对于生产率的增长有显著的促进作用,企业开工率通过技术效率可在短期内影响生产率的增长。 | 郑京海 刘小玄 Arne Bigsten | 2002 | 经济学(季刊)2002，1，3： | 54 |
| 5 | 内蒙古温都尔庙群变质火山——沉积岩钐-钕同位素研究显示文摘温都尔庙群主要系指在集(宁)-二(连浩特)铁路线以东,朱日和及其北部出露的一套中-浅变质海相火山沉积岩系.该套岩层以产出有温都尔庙式铁矿,非层序性蛇绿岩和高压变质矿物组合为国内外地质学界所关注,并且一直作为早古生代海沟存在的重要标志.鉴于温都尔庙群岩层遭受到不同程度构造变动和变质作用以及缺失可信的古生物化石,其时代归属众说纷纭. | 聂凤军 裴荣富 吴良士 Arne Bjφrlykke | 1994 | 科学通报1994，39，13： | 27 |
| 6 | The Uplift of the Longmenshan Thrust Belt and Subsidence of the West Sichuan Foreland Basin显示文摘Based on fission track dating of apatite, and measurement of vitrinite reflectance of rock samples from the Longmenshan (Longmen Mountain)area and the West Sichuan foreland basin and computer modelling it is concluded that (l)the Songpan-Garze fold belt has uplifted at least by 3-4 km with an uplift rate of no less than 0.3-0.4 mm/a since 10 Ma B.P.; (2) the Longmenshan thrust nappe belt has uplifted at least by 5-6 km with an uplift rate of more than 0.5- 0.6 mm /a since 10 Ma B.P.; (3) the Longmenshan detachment belt has uplifted by 1 - 2 km at a rate of 0.016-0.032 mm/a since 60 Ma B.P.; (4) the West Sichuan foreland basin has uplifted by 1.7-3 km at a rate of 0.028-0.05 mm/a since 60 Ma B.P.; (5) the uplift rate of the area on the west side of the Beichuan-Yingxiu-Xiaoguanzi fault for the last 10 Ma is 40 times as much as that on its east side; (6) the uplifting of the the Songpan - Garze fold belt and the subsidence of the West Sichuan foreland basin 60 Ma ago exhibit a mirro-image correlation, i. | Liu Shugen, Luo Zhili, Dai Sulan, Changlu Institute of Technology, Chengdu, Sichuan, ChinaDennis Arne Dalhousie U niversity, Canadaand C.J.L. Wilson Melbourne U niversity, Australia Jiang M inxi | 1996 | Acta Geologica Sinica(English Edition)1996，70，1： | 21 |
| 7 | A review on the performance of conventional and energy-absorbing rockbolts显示文摘This is a review paper on the performances of both conventional and energy-absorbing rockbolts manifested in laboratory tests. Characteristic parameters such as ultimate load, displacement and energy absorption are reported, in addition to loadedisplacement graphs for every type of rockbolt. Conventional rockbolts refer to mechanical rockbolts, fully-grouted rebars and frictional rockbolts. According to the test results, under static pull loading a mechanical rockbolt usually fails at the plate; a fully-grouted rebar bolt fails in the bolt shank at an ultimate load equal to the strength of the steel after a small amount of displacement; and a frictional rockbolt is subjected to large displacement at a low yield load. Under shear loading, all types of bolts fail in the shank. Energy-absorbing rockbolts are developed aiming to combat instability problems in burst-prone and squeezing rock conditions. They absorb deformation energy either through ploughing/slippage at predefined load levels or through stretching of the steel bolt. An energy-absorbing rockbolt can carry a high load and also accommodate significant rock displacement, and thus its energy-absorbing capacity is high. The test results show that the energy absorption of the energy-absorbing bolts is much larger than that of all conventional bolts. The dynamic load capacity is smaller than the static load capacity for the energy-absorbing bolts displacing based on ploughing/slippage while they are approximately the same for the D-Bolt that displaces based on steel stretching. | Charlie C.Li Gisle Stjern Arne Myrvang | 2014 | Journal of Rock Mechanics and Geotechnical Engineering2014，6，4： | 19 |
| 8 | Transarterial chemoembolization using degradable starch microspheres and iodized oil in the treatment of advanced hepatocellular carcinoma: evaluation of tumor response, toxicity, and survival显示文摘BACKGROUND: In a multidisciplinary conference patients with advanced non-resectable hepatocellular carcinoma (HCC) were stratified according to their clinical status and tumor extent to different regional modalities or to best supportive care. The present study evaluated all patients who were stratified to repeated transarterial chemoembolization (TACE) from 1999 until 2003 in terms of tumor response, toxicity, and survival. A moderate embolizing approach was chosen using a combination of degradable starch microspheres (DSM) and iodized oil (Lipiodol) in order to combine anti-tumoral efficiency and low toxicity. METHODS: Fourty-seven patients were followed up prospectively. TACE treatment consisted of cisplatin (50 mg/m2), doxorubicin (50 mg/m2), 450-900 mg DSM, and 5-30 ml Lipiodol. DSM and Lipiodol were administered according to tumor vascularization. Patient characteristics,toxicity, and complications were outlined. In multivariate regression analyses of pre-treatment variables from a prospective database, predictors for tumor response and survival after TACE were determined. RESULTS: 112 TACE courses were performed (2.4±1.5 courses per patient). Mean maximum tumor size was 75 (± 43) mm, in 68% there was bilobar disease. Best response to TACE treatment was: progressive disease (PD) 9%, stable disease (SD) 55%, partial remission (PR) 36%, and complete remission (CR) 0%. Multivariate regression analyses identified tumor size ≤75 mm, tumor number ≤5, and tumor hypervascularization as predictors for PR. The overall 1-, 2-, and 3-year-survival rates were 75%, 59%, and 41%, respectively, and the median survival was 26 months. Low α-fetoprotein levels (<400 ng/ml) (Odds ratio=3.3) and PR as best response to TACE (Odds ratio=6.7) were significantly associated with long term survival (>30 months, R2=36%). Grade 3 toxicity occurred in 7.1% (n=8), and grade 4 toxicity in 3.6% (n=4) of all courses in terms of reversible leukopenia and thrombocytopenia. The incidence of major complications was 5.4% (n=6). All complications were managed conservatively. The mortality within 6 weeks after TACE was 2.1% (one patient). CONCLUSIONS: DSM and Lipiodol were combined successfully in the palliative TACE treatment of advanced HCC resulting in high rates of tumor response and survival at limited toxicity. Favourable tumor response was associated with tumor extent and vascularization. TACE using DSM and Lipiodol can be considered a suitable palliative measure in patients who might not tolerate long acting embolizing agents. | Timm D Kirchhoff Joerg S Bleck Arne Dettmer Ajay Chavan Herbert Rosenthal Sonja Merkesdal Bernd Frericks Lars Zender Nisar P Malek Tim F Greten Stefan Kubicka Michael P Manns Michael Galanski | 2007 | Hepatobiliary & Pancreatic Diseases International2007，6，3： | 15 |
| 9 | Combination of repeated single-session percutaneous ethanol injection and transarterial chemoembolisation compared to repeated single-session percutaneous ethanol injection in patients with non-resectable hepatocellular carcinoma显示文摘瞄准:为病人评估经皮的乙醇注射(PEI ) 的治疗效果与先进, non-resectable HCC 与 transarterial chemoembolisation 的联合相比(不作声) 并且重复单个会议的 PEI,独自重复了单个会议的 PEI,重复不作声独自一个,或最好的支持的照顾。方法:在学习时期期间接受了 PEI 治疗的所有病人根据物理地位和肿瘤程度被包括并且成层到下列治疗形式之一:联合不作声并且重复单个会议的 PEI,独自重复了单个会议的 PEI,重复不作声独自一个,或最好的支持的照顾。包括Okuda分类,门静脉血栓的存在,腹水的存在,肿瘤的数字,最大的肿瘤直径,和假胆硷酯酶( CHE )的临床的参数的预示的价值,以及孩子呸上演, alpha-fetoprotein (法新社),发烧,复杂并发症的发生在这些组之间被估计并且比较。幸存用 Kaplan-Meier 被决定,多,变量回归分析。结果:所有病人的 1 年、 3 年的幸存是 73% 和 47% 。在亚群分析,联合不作声, PEI (1 ) 与更长的幸存被联系(1- , 3- , 5 年的幸存:90% , 52% ,和 43%) 与 PEI 治疗相比独自一个(2 )(1- , 3- , 5 年的幸存:65% , 50% ,和 37%) 。(3 ) 在起始的层化以后的第二等的 PEI 产出可比较的结果不作声(1- , 3- , 5 年的幸存:91% , 40% ,和 30%) 当在到最好的支持的照顾(4 ) 的层化以后的 PEI 与减少的幸存被联系时(1- , 3- , 5 年的幸存:50% , 23% , 12%) 。除了选择治疗形式,为更好的幸存的预言者是肿瘤数字(n <
5 ) ,肿瘤尺寸(<
5 厘米) ,在 PEI 前的没有腹水,和在 PEI 以后的稳定的假胆硷酯酶(P <
0.05 ) 。在在 PEI 以后的 2 wk 以内的死亡是 2.8%(n = 3 ) 。有 24 (8.9%) 主修在包括部分肝梗塞,焦点的肝坏死,和肝脓肿的 PEI 以后的复杂并发症。所有复杂并发症能非通过手术被管理。结论:重复单个会议的 PEI 在有以可接受、可管理的复杂并发症率的先进 HCC 的病人是有效的。病人们成层到联合不作声, PEI 能比那些独自成层到重复 PEI 期望更长的幸存。而且,有在好临床的地位的大或多重的肿瘤的病人可以也从联合获利不作声并且为第二等的 PEI 的再考虑。 | Arne Dettmer Timm D Kirchhoff Michael Gebel Lars Zender Nisar P Malek Bernhard Panning Ajay Chavan Herbert Rosenthal Stefan Kubicka Susanne Krusche Sonja Merkesdal Michael Galanski Michael P Manns Joerg S Bleck | 2006 | World Journal of Gastroenterology2006，12，23： | 14 |
| 10 | Epidemiology of perforated peptic ulcer:Age-and gender-adjusted analysis of incidence and mortality显示文摘AIM:To investigate the epidemiological trends in inci-dence and mortality of perforated peptic ulcer(PPU)in a well-defined Norwegian population. METHODS:A retrospective,population-based,single-center,consecutive cohort study of all patients diag-nosed with benign perforated peptic ulcer.Included were both gastric and duodenal ulcer patients admitted to Stavanger University Hospital between January 2001 and December 2010.Ulcers with a malignant neoplasia diagnosis,verified by histology after biopsy or resection,were excluded.Patients were identified from the hospitals administrative electronic database using pertinent ICD-9 and ICD-10 codes(K25.1,K25.2,K25.5, K25.6,K26.1,K26.2,K26.5,K26.6).Additional searches using appropriate codes for relevant laparoscopic and open surgical procedures(e.g.,JDA 60,JDA 61,JDH 70 and JDH 71)were performed to enable a complete identification of all patients.Patient demographics,presentation patterns and clinical data were retrieved from hospital records and surgical notes.Crude and adjusted incidence and mortality rates were estimated by using national population demographics data. RESULTS:In the study period,a total of 172 patients with PPU were identified.The adjusted incidence rate for the overall 10-year period was 6.5 per 100 000 per year(95%CI:5.6-7.6)and the adjusted mortality rate for the overall 10-year period was 1.1 per 100 000 per year(95%CI:0.7-1.6).A non-significant decline in ad-justed incidence rate from 9.7 to 5.6 occurred during the decade.The standardized mortality ratio for the whole study period was 5.7(95%CI:3.9-8.2),while the total 30-d mortality was 16.3%.No difference in in-cidence or mortality was found between genders.However,for patients≥60 years,the incidence increased over 10-fold,and mortality more than 50-fold,compared to younger ages.The admission rates outside office hours were high with almost two out of three(63%) admissions seen at evening/night time shifts and/or during weekends.The observed seasonal variations in admissions were not statistically significant. CONCLUSION:The adjusted incidence rate,seasonal distribution and mortality rate was stable.PPU fre-quently presents outside regular work-hours.Increase in incidence and mortality occurs with older age. | Kenneth Thorsen Jon Arne Sreide Jan Terje Kvaly Tom Glomsaker Kjetil Sreide | 2013 | World Journal of Gastroenterology2013，19，3： | 14 |
| 11 | Redox-Dependent Regulation of the Stress-Induced Zinc-Finger Protein SAP12 in Arabidopsis thaliana显示文摘联系压力的蛋白质 SAP12 属于联系压力的蛋白质(树液) 与在 Arabidopsis thaliana 的 14 个成员一起的家庭。SAP12 包含二根 AN1 锌手指并且作为经历主要氧化还原作用依赖者 conformational 变化的蛋白质在斜 2D 氧化还原作用 SDSPAGE 被识别。它的抄本强烈以类似于 SAP10 的一种时间依赖者方式在冷、咸的应力下面被导致,与在 6 以后的高水平 ? 在 24 和 48 以后的 h 和减少的层次 ? h。抄本规定在 24 和 48 点压力标记 peroxiredoxin PrxIID 类似于那些 ? h。Recombinant SAP12 蛋白质在在非减少的 SDS polyacrylamide 胶化电气泳动由改变的 electrophoretic 活动性设想了的第四级的结构显示出氧化还原作用依赖者变化。氧化 oligomer 被高 dithiothreitol 集中减少,并且另外由 E。有低 dithiothreitol (DTT ) 的 coli thioredoxin TrxA 加 NADPH 依赖的 thioredoxin reductase 的集中或 NADPH。从西方的污点, SAP12 蛋白质数量被估计在 0.5 的范围 ? ng ? g ? 1 叶蛋白质。SAP12 蛋白质在盐和冷应力下面减少了。这些数据建议一个氧化还原作用在特别地在冷、咸的应力下面的植物房间的 SAP12 的连接状态的功能。 | Elke Stroeher Xin-Jia Wang Nils Roloff Peter Klein Arne Husemann Karl-Josef Dietz | 2009 | Molecular Plant2009，2，2： | 11 |
| 12 | 间歇性血流限制不能减少前十字韧带重建后萎缩(英文)显示文摘Background:A previous study has reported a 50% reduction in disuse atrophy of the quadriceps during the first 14 days after anterior cruciate ligament(ACL) reconstruction.A follow-up trial is needed to confirm these promising results.The present study aims to investigate the effect of an occlusion stimulus on quadriceps atrophy after ACL reconstruction.Methods:A total of 24 subjects participated in the study.They were randomized into two groups.Starting the 2nd day after surgery,the occlusion group received an occlusion stimulus for 5 min,followed by removal of the occlusive pressure for 3 min.This was repeated five times in one training session,twice daily.During the period of occlusive stimulus,the subjects performed 20 low load exercises for the quadriceps.The control group followed the same exercise protocol,but without the occlusion stimulus.Changes in quadriceps anatomical cross section area(ACSA) were measured using axial magnetic resonance(MR) images at 40% and 50% of the length of the femur.Results:Both groups had a significant reduction of quadriceps ACSA from 2 days before surgery to 16 days after surgery.During the intervention period,the occlusion group lost 13.8% ± 1.1%(mean ± SEM) and the control group lost 13.1% ± 1.0% of their quadriceps ACSA,respectively.There was no significant difference between the occlusion and control groups with regards to atrophy of the quadriceps muscles.Conclusion:In conflict with other studies using a similar protocol,application of blood flow restriction the first 14 days after ACL reconstruction did not reduce quadriceps ACSA muscle atrophy measured by MR in a population of athletes. | Erik Iversen Vibeke Rostad Arne Larmo | 2016 | Journal of Sport and Health Science2016，5，1： | 11 |
| 13 | Different antibiotic susceptibility between antrum and corpus of the stomach,a possible reason for treatment failure of Helicobacter pylori infection显示文摘AIM:To assess whether antibiotic resistance varies between the antrum and corpus of the stomach of patients that are either Helicobacter pylori(H.pylori)therapy-naive or pre-treated.METHODS:H.pylori strains were isolated from antrum and corpus biopsies from 66 patients that received a diagnostic gastroduodenoscopy for variant clinical indications.Antimicrobial susceptibility to amoxicillin,clarithromycin,tetracycline,metronidazole,levofloxacin and rifabutin was tested with the E-test method on IsoSensitest agar with 10 vol%defibrinated horse blood.In patients with a different antibiotic susceptibility pattern between the isolates from the antrum and corpus,DNA fingerprinting via random amplified polymorphic DNA analysis was performed to detect differences among DNA patterns of H.pylori isolates.RESULTS:Primary,secondary and tertiary resistance to clarithromycin was 6.9%,53.8%and 83.3%,retrospectively.Metronidazole and levofloxacin resistance also increased according to the number of previous treatments(17.2%,69.2%,83.3%;13.8%,23.1%,33.3%).Tertiary resistance to rifabutin was detected in12.5%of patients.In none of the 66 patients a resistance against amoxicillin or tetracycline was detectable.Discordant antibiotic susceptibility between antrum and corpus isolates for different antibiotics was seen in 15.2%(10/66)of the patients.Two out of those ten patients were naive to any H.pylori antibiotic treatment.The remaining eight patients previously received at least one eradication therapy.DNA fingerprinting analysis revealed no substantial differences among DNA patterns between antrum and corpus isolates in the majority of patients suggesting an infection with a single H.pylori strain.CONCLUSION:Different antibiotic susceptibility between antrum and corpus biopsies is a common phenomenon and a possible explanation for treatment failure.Resistant H.pylori strains may be missed if just one biopsy from one anatomic site of the stomach is taken for H.pylori susceptibility testing. | Michael Selgrad Ina Tammer Cosima Langner Jan Bornschein Julia Mei?le Arne Kandulski Mariya Varbanova Thomas Wex Dirk Schlüter Peter Malfertheiner | 2014 | World Journal of Gastroenterology2014，20，43： | 10 |
| 14 | 激光诱导击穿光谱技术对冶金样品中钢及炉渣的同时分析显示文摘本研究的初衷是开发一种不均匀冶金样品中钢和炉渣的快速、同时分析方法,以用于工艺控制。该方法基于激光诱导击穿光谱技术(LIBS)。选择激光诱导击穿光谱技术是因为它既可以分析导电材料又可分析非导电材料,并且相对来说不易受样品形状及表面光洁度的影响。产生的不均匀样品包含大量亚毫米级的渣颗粒,这些颗粒在单次LIBS分析中不能从周围的钢里面分离出来。因此提出了一种方法来对样品表面进行行扫描,扫描以大约0.5mm的分辨率和10 mm的步长来进行。激光的脉冲速率为20 Hz,扫描速度为1 mm/s。炉渣颗粒在行扫描中表现为钢的'污染区',在这个区域中有高浓度的一些元素,如钙、铝及硅。基于单点校准,提出了一种数学模型来逐步评定所得出的数据。首先,辨别出'干净'的钢区域,测定出钢的成分;第二步,测定出扫描总长度范围内的平均成分;最后一步,通过差减法计算出炉渣的成分平均值。这种方法被应用于几个多相取样器采集的样品的分析。发现钢中的碳、硅、锰、磷、硫及铝等元素都可被测定,仅有百分之几的相对标准偏差。而在炉渣中,分析的相对标准偏差会更高,几个重要元素在10%左右。这一方法有望进一步被开发应用于更小的非金属夹杂物的快速分析。 | BENGTSON Arne THOMAS Bjork | 2009 | 冶金分析2009，29，2： | 10 |
| 15 | High-fidelity replication of thermoplastic microneedles with open microfluidic channels显示文摘Development of microneedles for unskilled and painless collection of blood or drug delivery addresses the quality of healthcare through early intervention at point-of-care.Microneedles with submicron to millimeter features have been fabricated from materials such as metals,silicon,and polymers by subtractive machining or etching.However,to date,large-scale manufacture of hollow microneedles has been limited by the cost and complexity of microfabrication techniques.This paper reports a novel manufacturing method that may overcome the complexity of hollow microneedle fabrication.Prototype microneedles with open microfluidic channels are fabricated by laser stereolithography.Thermoplastic replicas are manufactured from these templates by soft-embossing with high fidelity at submicron resolution.The manufacturing advantages are(a)direct printing from computeraided design(CAD)drawing without the constraints imposed by subtractive machining or etching processes,(b)high-fidelity replication of prototype geometries with multiple reuses of elastomeric molds,(c)shorter manufacturing time compared to three-dimensional stereolithography,and(d)integration of microneedles with open-channel microfluidics.Future work will address development of open-channel microfluidics for drug delivery,fluid sampling and analysis. | Zahra Faraji Rad Robert E.Nordon Carl J.Anthony Lynne Bilston Philip D.Prewett Ji-Youn Arns Christoph H.Arns Liangchi Zhang Graham J.Davies | 2017 | Microsystems & Nanoengineering2017，3，1： | 9 |
| 16 | Biliary cholesterol secretion: More than a simple ABC显示文摘Biliary cholesterol secretion is a process important for 2 major disease complexes, atherosclerotic cardiovascular disease and cholesterol gallstone disease. With respect to cardiovascular disease, biliary cholesterol secretion is regarded as the f inal step for the elimination of cholesterol originating from cholesterol-laden macrophage foam cells in the vessel wall in a pathway named reverse cholesterol transport. On the other hand, cholesterol hypersecretion into the bile is considered the main pathophysiological determinant of cholesterol gallstone formation. This review summarizes current knowledge on the origins of cholesterol secreted into the bile as well as the relevant processes and transporters involved. Next to the established ATP-binding cassette (ABC) transporters mediating the biliary secretion of bile acids (ABCB11), phospholipids (ABCB4) and cholesterol (ABCG5/G8), special attention is given to emerging proteins that modulate or mediate biliary cholesterol secretion. In this regard, the potential impact of the phosphatidylserine flippase ATPase class Ⅰ type 8B member 1, the Niemann Pick C1-like protein 1 that mediatescholesterol absorption and the high density lipoprotein cholesterol uptake receptor, scavenger receptor class B type Ⅰ, is discussed. | Arne Dikkers Uwe JF Tietge | 2010 | World Journal of Gastroenterology2010，16，47： | 9 |
| 17 | Thioredoxin and glutaredoxin-mediated redox regulation of ribonucleotide reductase显示文摘Ribonucleotide reductase(RNR), the rate-limitingenzyme in DNA synthesis, catalyzes reduction of thedifferent ribonucleotides to their corresponding deoxyri-bonucleotides. The crucial role of RNR in DNA synthesishas made it an important target for the development ofantiviral and anticancer drugs. Taking account of the re-cent developments in this field of research, this reviewfocuses on the role of thioredoxin and glutaredoxin sys-tems in the redox reactions of the RNR catalysis. | Rajib Sengupta Arne Holmgren | 2014 | World Journal of Biological Chemistry2014，5，1： | 6 |
| 18 | Changes in fish diversity and community structure in the central and southern Yellow Sea from 2003 to 2015显示文摘The central and southern Yellow Sea is an important overwintering ground for many fish species in the Bohai Sea and Yellow Sea. For better understanding the status of the fish community after years of heavy exploitation, variations in fish community structure and diversity were analyzed using data from bottom trawls during 2003–2015. Five fish assemblage indices all showed fluctuations without clear trends from 2003 to 2015, yet there were strong positive and significant correlations(P < 0.05) among them. The top-five dominant species accounted for a high weight percentage(49.7%–82.1%) in the annual fish catch. Multivariate analysis showed that two year groups could be pooled for the fish community: Group Ⅰ consisted of the years 2006, 2007, 2008 and 2015, while Group Ⅱ consisted of the years 2003, 2004, 2005, 2009, 2010 and 2014; the groups aggregated with 63.71% similarity, indicating a high level of similarity among all years. The multivariate dispersion values were 1.455 and 0.818 for Groups Ⅰ and Ⅱ, respectively, indicating greater variances in fish assemblage structure in Group Ⅰ than that in Group Ⅱ. Similarity of percentage analysis demonstrated that the average similarities for Group Ⅰ and Group Ⅱ were 71.58% and 67.51%, respectively. Size-spectra analysis revealed no consistent trend in the intercept and slope( P > 0.05); there were also no significant differences between the slope of the size-spectra and fishing ef fort. The catch per unit ef fort and mean individual weight analyses of the whole fish assemblage both showed a significantly decreasing trend over time. Overall, the results showed that the fish community structure in the central and southern Yellow Sea was relatively stable from 2003 to 2015 and the study could be used as a reference for supporting ecosystem-based fishery management. | 陈云龙 单秀娟 金显仕 JOHANNESSEN Arne 杨涛 戴芳群 | 2018 | Journal of Oceanology and Limnology2018，36，3： | 5 |
| 19 | 中国的寄生性杜鹃及其宿主多样性(英文)显示文摘通过多年的调查资料、观鸟爱好者所提供的图片和文献整理,我们对多杜鹃寄生系统下的中国寄生性杜鹃及其宿主的多样性进行了系统研究。在中国分布的17种寄生性杜鹃中,迄今已发现11种杜鹃的宿主达55种,均为雀形目鸟类,隶属于15科,其中莺科、鸫科和画眉科分别占到寄生记录总数的 22.6%、20.8% 和 17.0%。大杜鹃(Cuculus canorus)的宿主种类最多(45.5%),是中国最常见、宿主多样性最丰富的寄生性杜鹃。不同种类的寄生性杜鹃的卵色不同,而且杜鹃与其宿主之间均呈现明显的卵色多态性,为典型的卵色协同进化。基于人眼观察,大杜鹃、小杜鹃(C. poliocephalus)和八声杜鹃(Cacomantis merulinus)的卵色均与其宿主高度模拟,而鹰鹃(Cuculus sparverioides)、中杜鹃(C. saturatus)和翠金鹃(Chrysococcyx maculatus)则产非模拟的卵。目前仍有6种寄生性杜鹃的宿主不详,亟待加强研究。 | 杨灿朝 梁伟 Anton ANTONOV 蔡燕 Brd G.STOKKE Frode FOSSφY Arne MOKSNES Eivin RφSKAFT | 2012 | Chinese Birds2012，，1： | 5 |
| 20 | Erbium-doped TeO2-coated Si3N4 waveguide amplifiers with 5 dB net gain显示文摘We demonstrate 5dB net gain in an erbium-doped tellurium-oxide-coated silicon nitride waveguide.The amplifier design leverages the high refractive index and high gain in erbium-doped tellurite glass as well as the ultralow losses and mature,reliable,and low-cost fabrication methods of silicon nitride waveguide technology.We show that the waveguide platform demonstrates low background propagation losses of 0.25dB/cm based on a ring resonator device with a Q factor of 1.3×10^6 at 1640 nm.We measure 5dB peak net gain at 1558 nm and>3dB of net gain across the C band in a 6.7 cm long waveguide for 35 m W of launched 1470 nm pump power.Gain per unit length of 1.7 and 1.4dB/cm is measured in a 2.2 cm long waveguide for 970 and 1470 nm pump wavelengths,respectively.Amplifier simulations predict that>10dB gain can be achieved across the C band simply by optimizing waveguide length and fiber-chip coupling.These results demonstrate a promising approach for the monolithic integration of compact erbium-doped waveguide amplifiers on silicon nitride chips and within silicon-based photonic integrated circuits. | HENRY C.FRANKIS HAMIDU M.MBONDE DAWSON B.BONNEVILLE CHENGLIN ZHANG RICHARD MATEMAN ARNE LEINSE JONATHAN D.B.BRADLEY | 2020 | Photonics Research2020，8，2： | 5 |
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