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| 1 | 高频超声内窥镜在喉疾病诊断中的应用研究显示文摘目的 研究高频超声内窥镜技术在喉病变 ,特别是喉癌诊断中的应用。方法 用可屈的小内径 (8~ 10F)高频 (10~ 2 0MHz)内窥镜式超声探头 ,对 45例患者行喉腔内无创伤检查。在探头频率 10MHz最大测及 3cm ,探头频率 2 0MHz最大测及 1.5cm ,超声图像上能准确测量出肿瘤垂直直径大小及位置。结果 其中检查出 3 2例喉癌 ,与周围组织相比 ,呈现出典型的反射矩阵波。在显微喉镜检查中 ,借助高频超声可扫查到T1声带癌 (13例 )、最小瘤体直径约 3mm的浸润癌。但 13例中有 6例探测不到肿瘤(假阴性 ) ,假阳性结果尚未发现。T2 ~T3 喉癌 (12例 )较易诊断 ,在声门上区和声门下区肿瘤较周围组织显示低回声区 ;T4 肿瘤 (7例 )侵犯甲状软骨 ,在超声图像肿瘤的低回声区与甲状软骨内膜的高回声区有明显的反差。另外测及喉良性病变 13例。结论 运用内窥镜式高频超声可在显微镜检查中对喉病变 ,特别是喉肿瘤的大小及相应浸润范围 ,作出更为准确的诊断 。 | 李勇 王惠忠 Arens C Glanz H 栾信庸 潘信良 许凤雷 | 2003 | 中华超声影像学杂志2003，12，12： | 6 |
| 2 | High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array显示文摘Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted breeding.In tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental cross.In rose breeding,crosses with unintended parents occur regularly.We developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one parent.One of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal parent.The densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 cM.Synteny with the strawberry(Fragaria vesca)genome was extensive.Rose ICM1 corresponded to F.vesca pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to Fv5.Rose ICM2 corresponded to parts of F.vesca pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6. | Mirjana Vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders | 2016 | Horticulture Research2016，3，1： | 6 |
| 3 | 接触性内镜在早期喉癌及其癌前病变诊断中的应用显示文摘目的探索接触性内镜对早期喉癌及其癌前病变行微创病理学诊断的可行性。方法86例喉病变患者,在显微支撑喉镜下,于喉内病变处黏膜涂1%美蓝染色,将60×和150×接触性内镜置于黏膜表面,观察其病理变化,并与活检结果比较。结果接触性内镜的电子图像可较清晰显示表面黏膜不同病变细胞及核的大小、形状、排列、胞浆比、致密度和着色情况,有无中空细胞、核角蛋白,黏膜下微血管的排列情况。病理改变包括:任克式水肿(n=8),慢性喉炎(n=15),喉乳头状瘤(n=8),黏膜白斑(n=9),声带非典型性增生(n=18),恶性肿瘤(n=22),其他6例。结论接触性内镜作为一种新的微创性辅助检查方法,可用于喉癌及其癌前病变的诊断和动态随访。 | 李勇 Arens C Glanz H | 2005 | 中国中西医结合耳鼻咽喉科杂志2005，13，5： | 4 |
| 4 | Treatment of Churg-Strauss syndrome without poor prognosis factors: a muhicenter, prospective, randomized, open label study of seventy-two patients显示文摘 | Ribi C Cohen P Pagnoux C Mahr A Arene J P Lauque D | 2008 | Arthritis Rheum2008，58，： | 1 |
| 5 | Wound infections after cardiac surgery-a wound scoring system may improve early detection 显示文摘 | Tegnell A Aren C Ohman L | 2002 | Scand Cardiovasc J2002，36，1： | 1 |
| 6 | Intra and postoperative cerebral complications of open heart surgery显示文摘 | Johansson T Aren C Fransson SG | 1995 | Scand J Thorac Cardiovasc Surg1995，29，1： | 1 |
| 7 | Endolaryngeal high-frequency ultrasound显示文摘 | Arens C Eistert B Glanz H | 1998 | Eur Arch Otorhinolaryngol1998，255，5： | 1 |
| 8 | PC-Fix and local in fection resistance influence of implant design on post operative infection development, clinical and experi mental results显示文摘 | Eijer H Hauke C Arens S | 2001 | Injury2001，32，2： | 1 |
| 9 | Endoscopic high-frequency ultrasound of the larynx显示文摘 | Arens C Glanz H | 1999 | Eur Arch Otorhinolaryngol1999，256，6： | 1 |
| 10 | Abdominal surgery in nonagenarians:short-term results显示文摘 | Arenal JJ de Teresa G Tinoco C | 2007 | Surg Today2007，37，12： | 1 |
| 11 | Can C plants faithfully record the carbon isotopic composition of atmospheric carbon dioxide显示文摘 | Arens N C Jahren A H Amundson R | 2000 | Paleobiology2000，26，1： | 1 |
| 12 | PC-Fix and local infection resistance--influence of implant design on postoperative infection development,clinical and experimental results显示文摘 | Eijer H Hauke C Arens S | 2001 | Injury2001，32，2： | 1 |
| 13 | Modelling 3D Spatial Objects in a Geo-DBMS Using a 3D Primitive 显示文摘 | ARENS C STOTER J VAN OOSTEROM P | 2005 | Computers & Geosciences2005，31，2： | 1 |
| 14 | Partial and whole-body thermal sensation and comfort-part II: non-uniform environmental conditions 显示文摘 | ARENS E ZHANG H HUIZENGA C | 2006 | Journal of Thermal Biology2006，31，2： | 1 |
| 15 | Query reformulation for dynamic information integration显示文摘 | Y Arens C A Knoblock W-M Shen | 1996 | Journal of Intelligent Information Systems1996，6，23： | 1 |
| 16 | Mobility of a remobilized parabolic dune in kennemerland, the netherlands 显示文摘 | Arens S M Slings Q deVries C N | 2004 | Geomorphology2004，59，： | 1 |
| 17 | Endoscopic high-frequency ultrasound of the larynx 显示文摘 | ARENS C GLANZ H | 1999 | Eur Arch Otorhinolaryngol1999，256，6： | 1 |
| 18 | Can C3 plants faithfully record the carbon isotopic composition of atmospheric carbon dioxide? 显示文摘 | Arens N C Jahren A H Amundson R | 2000 | Paleobiology2000，26，： | 1 |
| 19 | Modeling 3D spatial objects in a geo-DBMS using a 3D primitive显示文摘 | Arens C Stoter J Van Oosterom P | 2005 | Computers & Geosciences2005，31，2： | 1 |
| 20 | Terrestial record of methane hydrate dissociation in the early Cretaceous 显示文摘 | Jahren A H Arens N C Sarmiento G | 2001 | Geolohy2001，29，2： | 1 |
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