| 1 | Parenchyma-sparing pancreatectomies for benign or border-line tumors of the pancreas显示文摘Standard pancreatic resections, such as pancreaticoduodenectomy, distal pancreatectomy, or total pancreatectomy, result in an important loss of normal pancreatic parenchyma and may cause impairment of exocrine and endocrine function. Whilst these procedures are mandatory for malignant tumors, they seem to be too extensive for benign or border-line tumors, especially in patients with a long life expectancy. In recent years, there has been a growing interest in parenchyma-sparing pancreatic surgery with the aim of achieving better functional results without compromising oncological radicality in patients with benign, border-line or low-grade malignant tumors. Several limited resections have been introduced for isolated or multiple pancreatic lesions, depending on the location of the tumor: central pancreatectomy, duodenum-preserving pancreatic head resection with or without segmental duodenectomy, inferior head resection, dorsal pancreatectomy, excavation of the pancreatic head, middle-preserving pancreatectomy, and other multiple segmental resections. All these procedures are technically feasible in experienced hands,with very low mortality, although with high morbidity rate when compared to standard procedures. Pancreatic endocrine and exocrine function is better preserved with good quality of life in most of the patients, and tumor recurrence is uncommon. Careful patient selection and expertise in pancreatic surgery are crucial to achieve the best results. | Cosimo Sperti Valentina Beltrame Anna Caterina Milanetto Margherita Moro Sergio Pedrazzoli | 2010 | World Journal of Gastrointestinal Oncology2010，2，6： | 11 |
| 3 | Schistosomiasis in immigrants,refugees and travellers in an Italian referral centre for tropical diseases显示文摘Background:Schistosomiasis is one of the most important neglected tropical diseases.If unrecognised and untreated,the chronic infection can lead to irreversible complications.Methods:Retrospective observational study aimed at describing clinical history,laboratory findings and imaging presentation of imported schistosomiasis diagnosed at the Centre for Tropical Diseases,Sacro Cuore Don Calabria Hospital of Negrar,Verona,Italy from 2010 to 2014.The aim of our study was to assess differences in demographic characteristics,clinical presentation,laboratory data and ultrasound findings between immigrants/visiting friends and relatives(VFR)from endemic countries(endemic group)and expatriates/travellers(non-endemic group).Results:A total of 272 patients were retrieved:234 in the endemic and 38 in the non-endemic group.Most of the patients acquired schistosomiasis in Africa(97.4%).Symptoms were reported by 52.9%of the patients;abdominal pain(36%),macroscopic hematuria(11.3%),and genito-urinary symptoms(7.4%)being the most frequently reported.Increased IgE and blood eosinophilia were observed in 169(63.8%)and 130(47.8%)patients,respectively.The proportion of positive serology was 250/272(91.9%).The Circulating Cathodic Antigen CCA for Schistosoma mansoni was positive in 14/61 individuals(23%).At microscopy,infected subjects were 103/272(37.9%).The species of Schistosoma found were S.haematobium(47.6%),S.mansoni(46.6%)or both(5.8%).Schistosomiasis was classified as confirmed in 103(37.9%),probable in 165(60.6%)and suspected in 4(1.5%)cases using clinical presentation,laboratory data and ultrasound findings.The infection was further classified based on organ involvement:intestinal(17.9%),hepatosplenic(5.1%),urogenital(48.9%),and indeterminate(43.8%).The comparative analysis of endemic and non-endemic patients highlighted differences in sex and age.Endemic patients had more frequent ova identification(41.9%vs.13.2%,P<0.001)and increased IgE(70%vs.26.3%,P<0.001)when compared with non-endemic.Multivariate analyses showed that younger age,abnormal ultrasound findings and blood eosinophilia were significantly associated with positive microscopy(OR=0.94,OR=2.12,OR=1.98,respectively).Conclusions:Symptoms,eosinophilia and abnormal ultrasound findings were present in about half of patients,without differences between groups.Many patients had positive serology but negative microscopy,indicating that schistosomiasis might be misdiagnosed.A combination of diagnostic tools may facilitate the diagnosis. | Valentina Marchese Anna Beltrame Andrea Angheben Geraldo Badona Monteiro Giovanni Giorli Francesca Perandin Dora Buonfrate Zeno Bisoffi | 2018 | Infectious Diseases of Poverty2018，7，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员