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您的检索式：作者名="Anish Chandy"
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| 1 | In vivo antioxidant and hepatoprotective activity of methanolic extracts of Daucus carota seeds in experimental animals显示文摘Objective:To assess the In vivo anlioxid Fanl and hepaloproleclive activity of metlianolic exlracl of Daucus carota(D.carota) seeds in experimental animals.Methods:Methanolic extracts of D.carota seeds is used for hepatoproleclion assessment.Oxidative stress were induced in rats by thioacetamide 100 nig/kg s.c.in four groups of rats(two test,standard and toxic control). Two test groups received D.carota seeds extract[DCSE) at doses of 200 mg/kg and 400 mg/kg. Standard group received silymarin(25 mg/kg) and toxic control received only thioacetamide. Control group received only vehicle.On the 8th day animals were sacrificed and liver enzyme like serum glutamic pyruvic transaminase(SGPT),serum glutamic-oxaloacetic transaminase(SCOT) and alkaline phosphatase(ALP)were estimated in blood serum and antioxidant enzyme like superoxide disnuituse(SOD),cululase(CAT),glutathione reductase(CKD),glutathione peroxidase(GPX),glutalhione-S-transferase(GST)and lipid peroxidation(LPO)were estimated in liver homogcnatc.Results:A significant decrease in SGPT,SCOT and ALP levels was observed in all drug treated groups as compared to thioacetamide group(P<0.001) and in case of antioxidant enzyme a significant(P<0.001) increase in SOD.CAT,GRD,GPX and GST was observed in all dmg treated groups as compared with thioacetamide group.But in case of LPO a significant(P <0.001) reduction was observed as compared to toxic control group.Conclusions:DCSE has contributed lo the reduction of oxidative stress and the protection of liver in experimental rals. | Kamlesh Singh Nisha Singh Anish Chandy Ashish Manigauha | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，5： | 6 |
| 2 | A review of neglected tropical diseases:filariasis显示文摘Filariasis is result of parasitic infection caused by three specific kinds of round worm.Lymphatic filariasis is found in under developed region of South America,Central Africa,pacific and Caribbian.It has been found for centuries,with main symptoms as elephant like swelling of the arms,legs and genitals.It is estimate that 120 millions peoples in the world have lymphatic filariasis.The spread of diseases and the challenge encountered in its management are discussed along with a review on drugs against filariasis in this article.Detail on clinical effect of drugs on the infection,safety profile,status in clinical practices and drug resistances are also covered. | Anish Chandy Alok Singh Thakur Mukesh Pratap Singh Ashish Manigauha | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，7： | 1 |
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