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9篇 您的检索式:作者名="Angela MC"
    题名 作者 年代 出处 被引量
1Expanding the biotechnology potential of LactobaciUi through comparative genomics of 213 strains and associated genera显示文摘Sun Z Harris HMB Angela MC 2015Nature Communications2015,6,:1
2Chondroitin-4-Sulphate Reduced Oxidative Injury in Caerulein-lnduced Pancreatitis in Mice:The Involvement of NF-κB Translocation and Apoptosis Activation显示文摘Giuseppe MC Angela A Salvatore C 0,,06:1
3Nothing but skin and bone显示文摘Patrick Ross F Angela MC 2006Clin Invest2006,15,:1
4Impact of biliary stent-related events in patients diagnosed with advanced pancreatobiliary tumours receiving palliative chemotherapy显示文摘AIM: To determine the impact(morbidity/mortality) of biliary stent-related events(SRE)(cholangitis or stent obstruction) in chemotherapy-treated pancreaticobiliary patients.METHODS: All consecutive patients with advanced pancreatobiliary cancer and a biliary stent in-situ prior to starting palliative chemotherapy were identified retrospectively from local electronic case-note records(Jan 13 to Jan 15). The primary end-point was SRE rate and the time-to-SRE(defined as time from first stenting before chemotherapy to date of SRE). Progressionfree survival and overall survival were measured from the time of starting chemotherapy. Kaplan-Meier, Cox and Fine-Gray regression(univariate and multivariable) analyses were employed, as appropriate. For the analysis of time-to-SRE, death was considered as a competing event.RESULTS: Ninety-six out of 693 screened patients were eligible; 89% had a metal stent(the remainder were plastic). The median time of follow-up was 9.6 mo(range 2.2 to 26.4). Forty-one patients(43%)developed a SRE during follow-up [cholangitis(39%), stent obstruction(29%), both(32%)]. There were no significant differences in baseline characteristics between the SRE group and no-SRE groups. Recorded SRE-consequences were: none(37%), chemotherapy delay(24%), discontinuation(17%) and death(22%). The median time-to-SRE was 4.4 mo(95%CI: 3.6-5.5). Patients with severe comorbidities(P < 0.001) and patients with ≥ 2 baseline stents/biliary procedures [HR = 2.3(95%CI: 1.2-4.44), P = 0.010] had a shorter time-to-SRE on multivariable analysis. Stage was an independent prognostic factor for overall survival(P = 0.029) in the multivariable analysis adjusted for primary tumour site, performance status and development of SRE(SRE group vs no-SRE group).CONCLUSION: SREs are common and impact on patient's morbidity. Our results highlight the need for prospective studies exploring the role of prophylactic strategies to prevent/delay SREs.Angela Lamarca Christina Rigby Mairéad G Mc Namara Richard A Hubner Juan W Valle 2016World Journal of Gastroenterology2016,22,26:1
5Ketamine-associated urinary tractpathology:the tip of the Iceberg for urologists显示文摘Angela MC David AG 2008Br J Med Surg Urol2008,1,3:1
6One-year outcomes in survivors of the acute respiratory distress syndrome显示文摘Margaret SH Angela MC Catherine MT 2003N Engl J Med2003,348,8:1
7Ketamine associated urinary tractpathology: the tip of the Iceberg for urologists显示文摘Angela MC David AG 2008Br J Med Surg Urol2008,1,3:1
8Nothing but skin and bone 显示文摘Patrick Ross F Angela MC 2006J Clin Invest2006,15,:1
9Ketamine associated Urinary Tract Pathology:The Tip of the Iceberg for Urologists显示文摘Angela MC David AG 2008Br J Med Surg Urol2008,1,3:1
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