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| 1 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 2 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021，59，4： | 3 |
| 3 | Light-driven micro-tool equipped with a syringe function显示文摘Leveraging developments in microfabrication open new possibilities for optical manipulation.With the structural design freedom from three-dimensional printing capabilities of two-photon polymerization,we are starting to see the emergence of cleverly shaped‘light robots’or optically actuated micro-tools that closely resemble their macroscopic counterparts in function and sometimes even in form.In this work,we have fabricated a new type of light robot that is capable of loading and unloading cargo using photothermally induced convection currents within the body of the tool.We have demonstrated this using silica and polystyrene beads as cargo.The flow speeds of the cargo during loading and unloading are significantly larger than when using optical forces alone.This new type of light robot presents a mode of material transport that may have a significant impact on targeted drug delivery and nanofluidics injection. | Mark Jayson Villangca Darwin Palima Andrew Rafael Bañas Jesper Glückstad | 2016 | Light(Science & Applications)2016，5，1： | 2 |
| 4 | Population Pharmacokineticsof Dexmedetomidine in Critically 111 Patients 显示文摘 | Pyry AV Tuula AS Andrew W | 2013 | Clin Drug Investig2013，33，8： | 1 |
| 5 | Histological classification and stage of newly diagnosed bladder cancer in a population-based study from the Northeastern United States 显示文摘 | Schned AR Andrew AS Marsit CJ | 2008 | Scand J Urol Nephrol2008，42，3： | 1 |
| 6 | Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic 显示文摘 | Andrew AS Burgess JL Meza MM | 2006 | Environ Health Perspect2006，114，8： | 1 |
| 7 | Influence of Gender, Weight and Hispanic Ethnicity on Physical Activity in Tod- dlers显示文摘 | Marten AS Andrews A Kelly LA | 2015 | Medicine & Science in Sports & Exercise2015，47，5： | 1 |
| 8 | Arsenic activates EGFR pathway signaling in the lung显示文摘 | Andrew AS Mason RA Memoli V | 2009 | Toxicol Sci2009，109，2： | 1 |
| 9 | Medication Errors in Acute Cardiovascular and Stroke Patients 显示文摘 | Andrew DM Sarah AS Barbara L | 2010 | Circulation2010，，121： | 1 |
| 10 | COX-2 is expressed in human pulmonary, colonic, and mammary tumors 显示文摘 | Robert AS Andrew JD Demaretta R | 2000 | Cancer2000，89，12： | 1 |
| 11 | Visibility of wavelet quantization noise 显示文摘 | ANDREW B W GLORIA Y Y JOSHUA AS | 1997 | IEEETransactions on Image Processing1997，6，8： | 1 |
| 12 | Indoor and outdoor air pollution and lung cancer in New Hampshire and Vermont 显示文摘 | Sloan CD Andrew AS Gruber JF | 2012 | Toxicol Environ Chem2012，94，3： | 1 |
| 13 | Expression of the E-cadherin-catenin cell adhesion complex in primary squamous cell carcinomas of the head and neck and their nodal metastases 显示文摘 | Andrews NA Jones AS Helliwell TR | 1997 | Br J cancer1997，75，10： | 1 |
| 14 | Expression of the E-cadherin- catenin cell adherin complex in primary squamous cell carcinoma of the head and neck and their nodal metastases显示文摘 | Andrews NA Jones AS Helliwell TR | 1997 | Br J Cancer1997，75，10： | 1 |
| 15 | Washington显示文摘 | Ross Andrew Oliver Testimonial Hearsay as the Basis for Expert Opinion:The Intersection of the Confrontation Clause and Federal Rule of Evidence 703 after Crawford v | 2004 | Hastinqs Law Tournal2004，，5： | 1 |
| 16 | Dual-phase spiral CT angiography with volumetric 3d rendering for preoperative liver transplant evaluation:preliminary observations显示文摘 | Patricia AS Andrew SK David GH | 1998 | J Comput Assist Tomogr1998，22，6： | 1 |
| 17 | 显示文摘 | Andrew AS | 2003 | Environ Health Perspeet2003，111，： | 1 |
| 18 | Macroevolutionary insights into sedges (Carex: Cyperaceae): The effects of rapid chromosome number evolution on lineage diversification显示文摘Changes in holocentric chromosome number due to fission and fusion have direct and immediate effects on genome structure and recombination rates.These,in turn,may influence ecology and evolutionary trajectories profoundly.Sedges of the genus Carex(Cyperaceae)comprise ca.2000 species with holocentric chromosomes.The genus exhibits a phenomenal range in the chromosome number(2n=10−132)with almost not polyploidy.In this study,we integrated the most comprehensive cytogenetic and phylogenetic data for sedges with associated climatic and morphological data to investigate the hypothesis that high recombination rates are selected when evolutionary innovation is required,using chromosome number evolution as a proxy for recombination rate.We evaluated Ornstein-Uhlenbeck models to infer shifts in chromosome number equilibrium and selective regime.We also tested the relationship between chromosome number and diversification rates.Our analyses demonstrate significant correlations between morphology and climatic niche and chromosome number in Carex.Nevertheless,the amount of chromosomal variation that we are able to explain is very small.We recognized a large number of shifts in mean chromosome number,but a significantly lower number in climatic niche and morphology.We also detected a peak in diversification rates near intermediate recombination rates.In combination,these analyses point toward the importance of chromosome evolution to the evolutionary history of Carex.Our work suggests that the effect of chromosome evolution on recombination rates,not just on reproductive isolation,may be central to the evolutionary history of sedges. | José I.Márquez-Corro Santiago Martín-Bravo Pedro Jiménez-Mejías Andrew L.Hipp Daniel Spalink Robert F.C.Naczi Eric H.Roalson Modesto Luceño Marcial Escudero | 2021 | Journal of Systematics and Evolution2021，59，4： | 1 |
| 19 | Schwannoma of the left atrium: diagnostic evaluation and surgical resection显示文摘 | Andrew DF Rodney AS Dougias EW | 1994 | Ann Thorac Surg1994，57，： | 1 |
| 20 | Spreading depression determinesacute cellular damage in the hippocampal slice during oxygen/ glu-cose deprivation 显示文摘 | OBEIDAT AS ANDREW RD | 1998 | Eur J Neurosci1998，10，11： | 1 |
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