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1篇 您的检索式：作者名="Andrea Caff"

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		题名	作者	年代	出处	被引量
	1	Merkel cell carcinoma responsive to Etoposide:a case report and brief literature review显示文摘Merkel cell carcinoma(MCC),first described in 1972,is an aggressive primary cutaneous carcinoma able to incorporate both epithelial and neuroendocrine features.MCC mainly appears in individuals in their eighth decade and it is related to a high mortality rate.The etiology of this rare disease is not well-understood but ultraviolet radiation exposure,immune suppression,and aging have a consistent role in its pathogenesis.Usually,clinical lesions appear as asymptomatic coloured dermal nodules.The tumour can involve lymph nodes but further evaluation with imaging is recommended.The common approach for localized disease is surgical.This work reports a case of an 86-year-old man with locally advanced MCC where,based on clinical experience,oral mono-chemotherapy with single-agent etoposide was chosen as first-line therapy.A complete objective response was achieved in 2 months.	Chiara Ancona Andrea Caff Giovanni Manfredi Assanto Stefano Cordio	2016	Journal of Cancer Metastasis and Treatment2016，2，1：	0

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