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| 1 | 预期寿命估计对脊柱转移瘤手术选择与预后预测的临床意义显示文摘背景与目的:目前,临床上对脊柱转移瘤患者是否采取手术治疗以及如何选择手术仍然存在较大的争议。预期寿命的估计是手术选择的决定因素之一。本研究旨在评价Tokuhashi和Tomita评分系统这两种常用的预期寿命估计方法对硬膜外脊柱转移瘤患者手术选择与预后预测的临床价值。方法:对2001年1月至2004年4月丹麦奥胡斯大学医院脊柱外科中心收治的169例硬膜外脊柱转移瘤入组患者,术前用Tokuhashi与Tomita评分系统进行评分以及估计预期寿命,并结合Tomita脊柱肿瘤分型,选择实施手术分级治疗。术后6个月、12个月以及24个月分别进行前瞻性随访观察。对在预期寿命为“3个月内死亡”、“6个月内死亡”以及“12个月内死亡”的患者通过Tokuhashi与Tomita评分系统绘制受试者作业特征曲线(receiveroperatingcharacteristiccurves,ROC曲线),比较两个评分系统对预期寿命估计的准确性。同时采用Kaplan-Meier生存曲线分析法,计算Tokuhashi和Tomita评分系统各分数段患者术后的实际平均生存时间。结果:预期寿命分别为“3个月内死亡”、“6个月内死亡”以及“12个月内死亡”的病例ROC曲线分析显示,Tomita评分系统与Tokuhashi评分系统之间的差异均无显著性(各组P值分别为0.16、0.47与0.38)。Kaplan-Meier生存曲线分析显示,Tomita评分系统在4~7分之间对预后估计过高,Tokuhashi评分系统在0~8分之间对预后估计过低。结论:Tokuhashi和Tomita评分系统均可成功地预测脊柱转移瘤患者术后预后的情况。Tokuhashi评分系统可较为准确地预测生存期较短的患者,从而避免对这类患者做不必要的大手术。 | 邹学农 Anders Grejs 李海声 Kristian Hφy Ebbe S Hansen Cody Bünger | 2006 | 癌症2006，25，11： | 18 |
| 2 | Continuous distribution analysis of T2 relaxation in meat-an approach in the determination of water-holding capacity显示文摘 | Hanne C B Sune D Anders H K | 2002 | Meat Science2002，60，： | 1 |
| 3 | Seasonal changes of mechanisms maintaining clear water in a shallow lake with abundant Chara vegetation显示文摘 | IRMGARD B ANDERS H GUNNAR A | 2002 | Aquatic botany2002，72，： | 1 |
| 4 | Comparing regression coefficients between same-sample nested models using logit and probit: a new method 显示文摘 | KARLSON K B ANDERS H RICHARD B | 2013 | Sociological Methodology2013，42，1： | 1 |
| 5 | Monitoring environmental performance of the forestry supply chain using RFID显示文摘 | Anders B Martin E Janne H | 2011 | Computers in Industry2011，62，8： | 1 |
| 6 | Prostate specific antigen for early detection of prostate cancer: longitudinal study 显示文摘 | Benny H Mattias J Anders B | 2009 | BMJ2009，339，3： | 1 |
| 7 | Nonalcoholic steatohepatitis summary, of an AASLD Single Topic Conference 显示文摘 | NEU SCHW ANDER TETR I B A CALDW ELL S H | 2003 | Hepatology2003，37，： | 1 |
| 8 | Prediction of glaucoma- tous visual field loss by extrapolation of linear trends显示文摘 | Boel B Michael P V Anders H | 2009 | Archives of Ophthalmology2009，127，12： | 1 |
| 9 | Self-organized pedestrian crowd dynamics: experiments, simulations, and design soiutions 显示文摘 | Dirk H B Lubos B Anders J | 2005 | Transportation Science2005，39，1： | 1 |
| 10 | Prediction of glaucoma-tous visual field loss by extrapolation of linear trends显示文摘 | Boel B Michael P V Anders H | 2009 | Archives of Ophthalmology2009，127，12： | 1 |
| 11 | Lipid metabolism and adipokine levels in fatty acid-binding protein null and transgenic mice 显示文摘 | Ann V H Lisa Ann Smith Anders H B | 2005 | Am J Physiol Endocrinol Metab2005，290，： | 1 |
| 12 | Lipid metabolism and adipokine ievels in Fatty acid-binding protein null and transgenic mice 显示文摘 | ANN V H LISA A S ANDERS H B | 2005 | Am J Physiol Endocrinol Metab2005，290，： | 1 |
| 13 | Cellular sterol ester synthesis in plants is performed by an enzyme (phospholipid: sterol acyhransferase)gifferent from the yeast and mammalian Acyl-CoA: sterol acyhransferases显示文摘 | Antoni B Anders S C Bangquan H | 2005 | J Biol Chem2005，280，34： | 1 |
| 14 | Signaling Danger: Toll- Like Receptors and their potential roles in Kidney Disease 显示文摘 | Anders H J Banas B Sehlondorff D | 2004 | J Am Soc Nephrel2004，15，4： | 1 |
| 15 | Signaling danger: toll- like receptors and their potential roles in kidney disease显示文摘 | Anders H J Banas B Schlondorff D | 2004 | J Am Soc Nephrol2004，15，4： | 1 |
| 16 | Serial cultivation of adult human endothelium from the great saphenous vein 显示文摘 | Anders H Caroline C Lars B | 1992 | J Vasc Surg1992，16，： | 1 |
| 17 | Effect of high pressure , temperature , and storage on the color of porcine longissimus dorsi显示文摘 | Kathrine H B Gunilla L Anders H K et 01 | 2012 | Meat Science2012，92，4： | 1 |
| 18 | Spatial patterns of precip- itation and topography in the Himalaya显示文摘 | Anders A M Roe G H Hallet B | 2006 | Special Papers-Geo- logical Society of America2006，398，： | 1 |
| 19 | Comparative study oflow-field NMR relaxation measurements and two tra- ditionalmethods in the determination of water holding capacity of pork显示文摘 | Hanne C B Henrik J A Anders H K1 | 2001 | Meat Science2001，57，： | 1 |
| 20 | Self-organized pedestrian crowd dynamics: experiments, simulations, and design solutions显示文摘 | DIRK H LUBOS B ANDERS J T W | 2005 | Transportation Science2005，39，1： | 1 |
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