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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | A Methodological Framework for the Study of Residential Location and Travel-to-work Mode Choice under Central and Suburban Employment Destination patterns 显示文摘 | Amaya V Aisling R F | 2009 | Transportation Research Part A2009，43，： | 1 |
| 3 | Multiresistant Acinetobacter baumannii infections:epidemiology and management显示文摘 | Garnacho Montero J Amaya Villar R | 2010 | Curr Opin Infect Dis2010，23，4： | 1 |
| 4 | RANi-mediated silencing of the myo- inositol phosphate synthase gene (GmMIPS) in trans-genic soybean inhibited seed development and reduced phytate content 显示文摘 | Nunes A C S Vianna G R Cuneo F Amaya F J Capdeville G Rech E L Arogao F J L | 2006 | P[anta2006，224，1： | 1 |
| 5 | Biochemical and mutational analysis of glutamine synthetase type Ⅲ from the rumen anaerobe Ruminococcus albus 8显示文摘 | AMAYA K R KOCHERGINSKAYA S A MACKIE R I | 2005 | Bacteriology2005，187，21： | 1 |
| 6 | 1 W, highly efficient, ultra-broadband non-uniform distributed power amplifier in GaN 显示文摘 | ZHOU X ROY L AMAYA R E | 2013 | IEEE Trans Wireless Compon Lett2013，23，4： | 1 |
| 7 | Variation quality of characteristies associated with some spring 1B/1R translocation wheats显示文摘 | Pefia R J Amaya A Rajarams | 1990 | Cereal Sci1990，12，： | 1 |
| 8 | Multiresistant Acinetobacter baumannii infections: epidemiology and management 显示文摘 | GARNACHO MONTERO J AMAYA VILLAR R | 2010 | Curr Opin Infect Dis2010，23，4： | 1 |
| 9 | Gene expression analysis reveals marked differences in the transcriptome of infantile hemangioma endothelial cells compared to normal dermal microvaseular endothelial cells显示文摘 | Stiles J M Rowntree R K Amaya C | 2013 | Vasc Cell2013，5，1： | 1 |
| 10 | Variation in quality characteristics associated with some spring 1B/1R translocation wheats显示文摘 | Pena R J Amaya A Rajaram S | 1990 | Journal of Cereal Science1990，12，： | 1 |
| 11 | Propranolol treatment of infantile hemangioma endothelial cells:A molecular analysis显示文摘 | Stiles J Amaya C Pham R | 2012 | Exp Ther Med2012，4，4： | 1 |
| 12 | Some considerations in generatingcarotenoid data for food compositiontables显示文摘 | Delia B Amaya R | 2000 | Journal of FoodComposition and Anal- ysis2000，13，6： | 1 |
| 13 | Some considerations in generating carotenoid data for food composition tables显示文摘 | Delia B Amaya R | 2000 | Journal of Food Composition and Analysis2000，13，： | 1 |
| 14 | Source identification of heavy metals in pastureland by multivariate analysis in NW Spain显示文摘 | AMAYA F-U CRISTINA L-M ENRIQUE R | 2009 | J Hazard Materi2009，165，123： | 1 |
| 15 | Frog genetics: Xenopus tropicalis jumps into the future 显示文摘 | Amaya E Offield M F Grainger R M | 1998 | Trends in Genetics1998，14，7： | 1 |
| 16 | Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression correlated with tumor angiogenesis and macrophage infiltration in colorectal cancer显示文摘 | M Matsumura Y Chiba C Lu H Amaya T Shimomatsuya T Horiuchi R Muraoka N Tanigawa | 1998 | Cancer Letters1998，，1： | 1 |
| 17 | Variation in quality characteristics associated with some spring 1B/1R translocation wheats显示文摘 | Pena R J Amaya A Rajaram S | 1990 | Journal of Cereal Science1990，12，： | 1 |
| 18 | Influence of the enzyme derivative preparation and substrate structure on the enantiosetectivity of penicillin G acylase显示文摘 | Silvia R Amaya S Vicente U | 2002 | Enzyme and Microbial Technology2002，31，： | 1 |
| 19 | Effects of a leukocyte depleting arterial line filter on perioperative morbidity in patients undergoing cardiac surgery : a controlled randomized trial 显示文摘 | Lcal-Noval SR Amaya R Herruzo A | 2005 | Ann Thorae Surg2005，80，4： | 1 |
| 20 | Numerical solution of certain expo- nential and non-linear Diophantine systems of equations by using a discrete particle swarm optimization algorithm显示文摘 | P6rez O Amaya I Correa R | 2013 | Ap- plied Mathematics and Computation2013，225，： | 1 |
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