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| 1 | Blood classical monocytes phenotype is not altered in primary non-small cell lung cancer显示文摘AIM: To evaluate the M1 and M2 monocyte phenotype in patients with non-small cell lung cancer(NSCLC) compared to controls. Also, to examine the expression of Th1 and Th2 cytokines in plasma of NSCLC vs controls. METHODS: Freshly prepared peripheral blood mononuclear cells samples were obtained from patients with NSCLC(lung adenocarcinoma and squamous cell lung carcinoma) and from non-cancer controls. Flow cytometry was performed to investigate M1 and M2 phenotypes in peripheral monocytes(classical monocytes CD14+, CD45+ and CD16-) using conventional surface markers. Th1 and Th2 cytokine production was alsoanalysed in the plasma using cytometric bead array technique. RESULTS: There were no significant difference in expression of M1(HLA-DR) and/or M2 markers(CD163 and CD36) markers on classical monocytes in patients with NSCLC compared to non-cancer controls. Expression of CD11 b, CD11 c, CD71 and CD44 was also shown to be similar in patients with NSCLC compared to noncancer controls. Th1 and Th2 cytokines [interleukin(IL)-1β, IL-2, IL-4, IL-5, IL-8, IL-10, IL-12(p70), tumor necrosis factor(TNF)-α, TNF-β, and interferon-γ] analysis revealed no significant difference between patients with NSCLC and non-cancer controls. CONCLUSION: This study shows no alteration in peripheral monocyte phenotype in circulating classical monocytes in patients with NSCLC compared to noncancer controls. No difference in Th1 and Th2 cytokine levels were noted in the plasma of these patients. | Saleh A Almatroodi Christine F Mc Donald Allison L Collins I an A Darby Dodie S Pouniotis | 2014 | World Journal of Clinical Oncology2014，5，5： | 2 |
| 2 | Randomised comparison of percutaneous endoscopic gastrostomy and nasogastric tube feeding in patients with persisting neurological dysphagia 显示文摘 | Park RH Allison MC Lang J | 1992 | BMJ1992，304，6839： | 1 |
| 3 | Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs 显示文摘 | Allison MC Howatson AG Torrance C J | 1992 | N Engl J Med1992，327，11： | 1 |
| 4 | Antibiotic prophylaxis in gastrointestinal endoscopy显示文摘 | Allison MC Sandoe JA Tighe R | 2009 | Gut2009，58，6： | 1 |
| 5 | Randomised comparison of percutaneous endoscopic gastrostomy and nasogastric tube feeding in patients with persisting neurological dysphagia 显示文摘 | Park RH Allison MC Lang J | 1992 | BMJ1992，304，6839： | 1 |
| 6 | Improved oxygen delignification with peroxyacid treatment显示文摘 | Mc Grouther K G Allison R W | 1994 | Appita1994，47，3： | 1 |
| 7 | Tht pedicled intercostals neuro- vascular islang skin flap for lumbosacral trunk reconstruction 显示文摘 | Wong MC Allison K Yap LH | 2004 | Br J Plast Surg2004，57，6： | 1 |
| 8 | Use of Second-generation antiepileptic drugs in the pediatric population显示文摘 | Allison MC Lea SE | 2008 | Pediatr Drugs2008，10，4： | 1 |
| 9 | Optimizing the effects of interestage peroxymonosulphate treatment on two stage oxygen delignification显示文摘 | Allison R W Mc Grouther K G Euis M J | 1997 | Journal of Pulp and Paper Science1997，23，9： | 1 |
| 10 | Antibiotic prophylaxis in gastroin-testinal endoscopy 显示文摘 | Allison MC Sandoe JA Tighe R | 2009 | Gut2009，58，6： | 1 |
| 11 | Effects of drying methods and additives on structure and function of actin: mechanisms of dehydration-induced damage and its inhibition显示文摘 | Allison SD Randolph TW Manning MC | 1998 | Arch Biochem Biophys1998，358，1： | 1 |
| 12 | The prevalence of iron deficiency among patients presenting with colorectal cancer 显示文摘 | Beale AL Penney MD Allison MC | 2005 | Colorectal Disease2005，7，4： | 1 |
| 13 | Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs显示文摘 | Allison MC Howatson AG Torrance C J | 1992 | N Engl J Med1992，327，： | 1 |
| 14 | A randomized placebo-controlled trial of a humanized monoclonal antibody to alpha4 integrin in active Crohn's disease显示文摘 | Gordon FH Lai CW Hamilton MI Allison MC Srivastava ED Fouweather MG Donoghue S Greenlees C Subhani J Amlot PL Pounder RE | 2001 | Gastroenterology2001，121，2： | 1 |
| 15 | Optimization of storage stability of lyophilized actin using combinations of disaccharides and dextran显示文摘 | Allison SD Manning MC Randolph TW | 2000 | J Pharm Sci2000，89，2： | 1 |
| 16 | Randomised comparison of percutaneous endoscopic gastrostomy and nasogastrie tube feeding in patients with persisting neurological dysphagia 显示文摘 | Park RH Allison MC Lang J | 1992 | BMJ 19921992，，： | 1 |
| 17 | Randomised comparison of percutaneous endoscopic gastrostomy and nasogastric tube feeding in patients with persisting neurological dysphagla显示文摘 | Park RHR Allison MC Lang J | 1992 | BMJ1992，304，： | 1 |
| 18 | Randomised comparison of percutaneous endoscopic gastrostomy and nasogastric tube feeding in patients with persisting neurological dysphagla显示文摘 | Park RHR Allison MC Lang J | 1992 | BMJ1992，304，： | 1 |
| 19 | Percutaneous endoscopic gastrostomy tube feeding may improve outcome of late rehabilitation following stroke 显示文摘 | Allison MC Morris A J Park RH | 1992 | J R Soc Med1992，85，3： | 1 |
| 20 | Use of Second-generation antiepileptic drugs in the pediatric population 显示文摘 | Allison MC Lea SE | 2008 | Pediatr Drugs2008，10，4： | 1 |
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