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您的检索式：作者名="Allison E.Fetz"
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| 1 | An overview of the role of neutrophils in innate immunity,inflammation and host-biomaterial integration显示文摘Despite considerable recent progress in defining neutrophil functions and behaviors in tissue repair,much remains to be determined with regards to its overall role in the tissue integration of biomaterials.This article provides an overview of the neutrophil’s numerous,important roles in both inflammation and resolution,and subsequently,their role in biomaterial integration.Neutrophils function in three primary capacities:generation of oxidative bursts,release of granules and formation of neutrophil extracellular traps(NETs);these combined functions enable neutrophil involvement in inflammation,macrophage recruitment,M2 macrophage differentiation,resolution of inflammation,angiogenesis,tumor formation and immune system activation.Neutrophils exhibit great flexibility to adjust to the prevalent microenvironmental conditions in the tissue;thus,the biomaterial composition and fabrication will potentially influence neutrophil behavior following confrontation.This review serves to highlight the neutrophil’s plasticity,reiterating that neutrophils are not just simple suicidal killers,but the true maestros of resolution and regeneration. | Gretchen S.Selders Allison E.Fetz Marko Z.Radic Gary L.Bowlin | 2017 | Regenerative Biomaterials2017，4，1： | 14 |
| 2 | Electrospinning nanofiber scaffolds for soft and hard tissue regeneration显示文摘Tissue engineering is an interdisciplinary field that integrates medical,biological,and engineering expertise to restore or regenerate the functionality of healthy tissues and organs.The three fundamental pillars of tissue engineering are scaffolds,cells,and biomolecules.Electrospun nanofibers have been successfully used as scaffolds for a variety of tissue engineering applications because they are biomimetic of the natural,fibrous extracellular matrix(ECM)and contain a three-dimensional(3D)network of interconnected pores.In this review,we provide an overview of the electrospinning process,its principles,and the application of the resultant electrospun nanofibers for tissue engineering.We first briefly introduce the electrospinning process and then cover its principles and standard equipment for biomaterial fabrication.Next,we highlight the most important and recent advances related to the applications of electrospun nanofibers in tissue engineering,including skin,blood vessels,nerves,bone,cartilage,and tendon/ligament applications.Finally,we conclude with current advancements in the fabrication of electrospun nanofiber scaffolds and their biomedical applications in emerging areas. | Xianrui Xie Yujie Chen Xiaoyu Wang Xiaoqing Xu Yihong Shen Atta ur Rehman Khan Ali Aldalbahi Allison E.Fetz Gary L.Bowlin Mohamed El-Newehy Xiumei Mo | 2020 | Journal of Materials Science & Technology2020，59，24： | 5 |
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